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199 related items for PubMed ID: 14521601

  • 1. Enhanced in vitro procoagulant and antifibrinolytic potential of superactive variants of recombinant factor VIIa in severe hemophilia A.
    Lisman T, de Groot PG, Lambert T, Røjkjaer R, Persson E.
    J Thromb Haemost; 2003 Oct; 1(10):2175-8. PubMed ID: 14521601
    [Abstract] [Full Text] [Related]

  • 2. A variant of recombinant factor VIIa with enhanced procoagulant and antifibrinolytic activities in an in vitro model of hemophilia.
    Allen GA, Persson E, Campbell RA, Ezban M, Hedner U, Wolberg AS.
    Arterioscler Thromb Vasc Biol; 2007 Mar; 27(3):683-9. PubMed ID: 17204663
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of fibrinolysis by recombinant factor VIIa in plasma from patients with severe hemophilia A.
    Lisman T, Mosnier LO, Lambert T, Mauser-Bunschoten EP, Meijers JC, Nieuwenhuis HK, de Groot PG.
    Blood; 2002 Jan 01; 99(1):175-9. PubMed ID: 11756168
    [Abstract] [Full Text] [Related]

  • 4. Recombinant factor VIIa analog NN1731 (V158D/E296V/M298Q-FVIIa) enhances fibrin formation, structure and stability in lipidated hemophilic plasma.
    Gray LD, Hussey MA, Larson BM, Machlus KR, Campbell RA, Koch G, Ezban M, Hedner U, Wolberg AS.
    Thromb Res; 2011 Dec 01; 128(6):570-6. PubMed ID: 21561645
    [Abstract] [Full Text] [Related]

  • 5. Overall haemostatic potential can be used for estimation of thrombin-activatable fibrinolysis inhibitor-dependent fibrinolysis in vivo and for possible follow-up of recombinant factor VIIa treatment in patients with inhibitors to factor VIII.
    Antovic JP, Antovic A, He S, Tengborn L, Blombäck M.
    Haemophilia; 2002 Nov 01; 8(6):781-6. PubMed ID: 12410647
    [Abstract] [Full Text] [Related]

  • 6. Pharmacological concentrations of recombinant factor VIIa restore hemostasis independent of tissue factor in antibody-induced hemophilia mice.
    Keshava S, Sundaram J, Rajulapati A, Pendurthi UR, Rao LV.
    J Thromb Haemost; 2016 Mar 01; 14(3):546-50. PubMed ID: 26727350
    [Abstract] [Full Text] [Related]

  • 7. Factor VIIa analogue (V158D/E296V/M298Q-FVIIa) normalises clot formation in whole blood from patients with severe haemophilia A.
    Sørensen B, Persson E, Ingerslev J.
    Br J Haematol; 2007 Apr 01; 137(2):158-65. PubMed ID: 17391496
    [Abstract] [Full Text] [Related]

  • 8. In vitro evidence of a tissue factor-independent mode of action of recombinant factor VIIa in hemophilia.
    Augustsson C, Persson E.
    Blood; 2014 Nov 13; 124(20):3172-4. PubMed ID: 25232061
    [Abstract] [Full Text] [Related]

  • 9. Thrombin generation and fibrinolysis in anti-factor IX treated blood and plasma spiked with factor VIII inhibitor bypassing activity or recombinant factor VIIa.
    Bolliger D, Szlam F, Molinaro RJ, Escobar MA, Levy JH, Tanaka KA.
    Haemophilia; 2010 May 13; 16(3):510-7. PubMed ID: 20050927
    [Abstract] [Full Text] [Related]

  • 10. Effects of recombinant activated factor VII on thrombin-mediated feedback activation of coagulation.
    Taketomi T, Szlam F, Bader SO, Sheppard CA, Levy JH, Tanaka KA.
    Blood Coagul Fibrinolysis; 2008 Mar 13; 19(2):135-41. PubMed ID: 18277134
    [Abstract] [Full Text] [Related]

  • 11. Factor XIII cotreatment with hemostatic agents in hemophilia A increases fibrin α-chain crosslinking.
    Beckman JD, Holle LA, Wolberg AS.
    J Thromb Haemost; 2018 Jan 13; 16(1):131-141. PubMed ID: 29080382
    [Abstract] [Full Text] [Related]

  • 12. Clot lysis phenotype and response to recombinant factor VIIa in plasma of haemophilia A inhibitor patients.
    Bakhtiari K, Kamphuisen PW, Mancuso ME, Hamulyak K, Schutgens RE, Santagostino E, Meijers JC.
    Br J Haematol; 2013 Sep 13; 162(6):827-35. PubMed ID: 23889493
    [Abstract] [Full Text] [Related]

  • 13. Whole blood clot formation phenotypes in hemophilia A and rare coagulation disorders. Patterns of response to recombinant factor VIIa.
    Sørensen B, Ingerslev J.
    J Thromb Haemost; 2004 Jan 13; 2(1):102-10. PubMed ID: 14717973
    [Abstract] [Full Text] [Related]

  • 14. Recombinant factor VIIa improves clot formation but not fibrolytic potential in patients with cirrhosis and during liver transplantation.
    Lisman T, Leebeek FW, Meijer K, Van Der Meer J, Nieuwenhuis HK, De Groot PG.
    Hepatology; 2002 Mar 13; 35(3):616-21. PubMed ID: 11870375
    [Abstract] [Full Text] [Related]

  • 15. Prerequisites for recombinant factor VIIa-induced thrombin generation in plasmas deficient in factors VIII, IX or XI.
    Livnat T, Zivelin A, Martinowitz U, Salomon O, Seligsohn U.
    J Thromb Haemost; 2006 Jan 13; 4(1):192-200. PubMed ID: 16409469
    [Abstract] [Full Text] [Related]

  • 16. Improved hemostasis with superactive analogs of factor VIIa in a mouse model of hemophilia A.
    Tranholm M, Kristensen K, Kristensen AT, Pyke C, Røjkjaer R, Persson E.
    Blood; 2003 Nov 15; 102(10):3615-20. PubMed ID: 12869500
    [Abstract] [Full Text] [Related]

  • 17. Factor VIII activation by factor VIIa analog (V158D/E296V/M298Q) in tissue factor-independent mechanisms.
    Ogiwara K, Nogami K, Shima M.
    Thromb Haemost; 2011 Oct 15; 106(4):665-74. PubMed ID: 21901232
    [Abstract] [Full Text] [Related]

  • 18. Potential role of recombinant factor VIIa as a hemostatic agent.
    Hedner U, Erhardtsen E.
    Clin Adv Hematol Oncol; 2003 Feb 15; 1(2):112-9. PubMed ID: 16224390
    [Abstract] [Full Text] [Related]

  • 19. A novel approach to improving recombinant factor VIIa activity with a preserved platelet preparation.
    Campbell RA, Fischer TH, Wolberg AS.
    Br J Haematol; 2007 Jul 15; 138(1):82-93. PubMed ID: 17555451
    [Abstract] [Full Text] [Related]

  • 20. Recombinant factor VIIa addition to haemophilic blood perfused over collagen/tissue factor can sufficiently bypass the factor IXa/VIIIa defect to rescue fibrin generation.
    Li R, Panckeri KA, Fogarty PF, Cuker A, Diamond SL.
    Haemophilia; 2017 Sep 15; 23(5):759-768. PubMed ID: 28475272
    [Abstract] [Full Text] [Related]

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