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176 related items for PubMed ID: 14522930

  • 1. Role of GRP58 in mitomycin C-induced DNA cross-linking.
    Celli CM, Jaiswal AK.
    Cancer Res; 2003 Sep 15; 63(18):6016-25. PubMed ID: 14522930
    [Abstract] [Full Text] [Related]

  • 2. A unique cytosolic activity related but distinct from NQO1 catalyses metabolic activation of mitomycin C.
    Joseph P, Jaiswal AK.
    Br J Cancer; 2000 Apr 15; 82(7):1305-11. PubMed ID: 10755406
    [Abstract] [Full Text] [Related]

  • 3. NRH:quinone oxidoreductase 2 (NQO2) catalyzes metabolic activation of quinones and anti-tumor drugs.
    Celli CM, Tran N, Knox R, Jaiswal AK.
    Biochem Pharmacol; 2006 Jul 28; 72(3):366-76. PubMed ID: 16765324
    [Abstract] [Full Text] [Related]

  • 4. Thioredoxin-like domains required for glucose regulatory protein 58 mediated reductive activation of mitomycin C leading to DNA cross-linking.
    Adikesavan AK, Jaiswal AK.
    Mol Cancer Ther; 2007 Oct 28; 6(10):2719-27. PubMed ID: 17938265
    [Abstract] [Full Text] [Related]

  • 5. Enzymatic and pH modulation of mitomycin C-induced DNA damage in mitomycin C-resistant HCT 116 human colon cancer cells.
    Pan SS, Yu F, Hipsher C.
    Mol Pharmacol; 1993 Jun 28; 43(6):870-7. PubMed ID: 8316219
    [Abstract] [Full Text] [Related]

  • 6. Non-enzymatic and enzymatic activation of mitomycin C: identification of a unique cytosolic activity.
    Joseph P, Xu Y, Jaiswal AK.
    Int J Cancer; 1996 Jan 17; 65(2):263-71. PubMed ID: 8567127
    [Abstract] [Full Text] [Related]

  • 7. Kinetics of NAD(P)H:quinone oxidoreductase I (NQO1) inhibition by mitomycin C in vitro and in vivo.
    Gustafson DL, Siegel D, Rastatter JC, Merz AL, Parpal JC, Kepa JK, Ross D, Long ME.
    J Pharmacol Exp Ther; 2003 Jun 17; 305(3):1079-86. PubMed ID: 12649308
    [Abstract] [Full Text] [Related]

  • 8. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.
    Traver RD, Horikoshi T, Danenberg KD, Stadlbauer TH, Danenberg PV, Ross D, Gibson NW.
    Cancer Res; 1992 Feb 15; 52(4):797-802. PubMed ID: 1737339
    [Abstract] [Full Text] [Related]

  • 9. DT-diaphorase as a target enzyme for biochemical modulation of mitomycin C.
    Saeki S, Nishiyama M, Toge T.
    Hiroshima J Med Sci; 1995 Sep 15; 44(3):55-63. PubMed ID: 8567314
    [Abstract] [Full Text] [Related]

  • 10. Tumor-specific synergistic therapy of mitomycin C: modulation of bioreductive activation.
    Sakamoto N, Toge T, Nishiyama M.
    Hiroshima J Med Sci; 1997 Jun 15; 46(2):67-73. PubMed ID: 9232934
    [Abstract] [Full Text] [Related]

  • 11. NAD(P)H:quinone oxidoreductase expression and mitomycin C resistance developed by human colon cancer HCT 116 cells.
    Pan SS, Forrest GL, Akman SA, Hu LT.
    Cancer Res; 1995 Jan 15; 55(2):330-5. PubMed ID: 7812966
    [Abstract] [Full Text] [Related]

  • 12. Expression of DT-diaphorase and cytochrome P450 reductase correlates with mitomycin C activity in human bladder tumors.
    Gan Y, Mo Y, Kalns JE, Lu J, Danenberg K, Danenberg P, Wientjes MG, Au JL.
    Clin Cancer Res; 2001 May 15; 7(5):1313-9. PubMed ID: 11350900
    [Abstract] [Full Text] [Related]

  • 13. A glucose-regulated protein, GRP58, is down-regulated in C57B6 mouse liver after diethylhexyl phthalate exposure.
    Muhlenkamp CR, Gill SS.
    Toxicol Appl Pharmacol; 1998 Jan 15; 148(1):101-8. PubMed ID: 9465269
    [Abstract] [Full Text] [Related]

  • 14. Predicting tumor responses to mitomycin C on the basis of DT-diaphorase activity or drug metabolism by tumor homogenates: implications for enzyme-directed bioreductive drug development.
    Phillips RM, Burger AM, Loadman PM, Jarrett CM, Swaine DJ, Fiebig HH.
    Cancer Res; 2000 Nov 15; 60(22):6384-90. PubMed ID: 11103802
    [Abstract] [Full Text] [Related]

  • 15. Curcumin reduced the side effects of mitomycin C by inhibiting GRP58-mediated DNA cross-linking in MCF-7 breast cancer xenografts.
    Zhou QM, Zhang H, Lu YY, Wang XF, Su SB.
    Cancer Sci; 2009 Nov 15; 100(11):2040-5. PubMed ID: 19703194
    [Abstract] [Full Text] [Related]

  • 16. Mitomycin C resistance induced by TCF-3 overexpression in gastric cancer cell line MKN28 is associated with DT-diaphorase down-regulation.
    Sagara N, Katoh M.
    Cancer Res; 2000 Nov 01; 60(21):5959-62. PubMed ID: 11085512
    [Abstract] [Full Text] [Related]

  • 17. Arsenite pretreatment enhances the cytotoxicity of mitomycin C in human cancer cell lines via increased NAD(P)H quinone oxidoreductase 1 expression.
    Lin YL, Ho IC, Su PF, Lee TC.
    Toxicol Appl Pharmacol; 2006 Aug 01; 214(3):309-17. PubMed ID: 16494910
    [Abstract] [Full Text] [Related]

  • 18. [Mechanism of resistance to mitomycin C in a human bladder cancer cell line].
    Xu B, Sun Y, Singh SV.
    Zhonghua Zhong Liu Za Zhi; 1995 Sep 01; 17(5):343-6. PubMed ID: 8697971
    [Abstract] [Full Text] [Related]

  • 19. DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines.
    Mikami K, Naito M, Tomida A, Yamada M, Sirakusa T, Tsuruo T.
    Cancer Res; 1996 Jun 15; 56(12):2823-6. PubMed ID: 8665520
    [Abstract] [Full Text] [Related]

  • 20. [DT-diaphorase].
    Mikami K, Shirakusa T, Tsuruo T.
    Gan To Kagaku Ryoho; 1997 Sep 15; 24(11):1606-10. PubMed ID: 9309161
    [Abstract] [Full Text] [Related]

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