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176 related items for PubMed ID: 14522930

  • 21. [Mitomycin C and its bioreduction: relevance of NAD(P)H: quinone oxidoreductase activity to mitomycin C-induced DNA damage and cytotoxicity].
    Nishiyama M, Saeki S, Aogi K, Hirabayashi N, Toge T.
    Gan To Kagaku Ryoho; 1993 Jun; 20(8):1037-41. PubMed ID: 7685584
    [Abstract] [Full Text] [Related]

  • 22. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under acidic conditions.
    Begleiter A, Leith MK.
    Mol Pharmacol; 1993 Jul; 44(1):210-5. PubMed ID: 8341273
    [Abstract] [Full Text] [Related]

  • 23. Association of the chaperone glucose-regulated protein 58 (GRP58/ER-60/ERp57) with Stat3 in cytosol and plasma membrane complexes.
    Guo GG, Patel K, Kumar V, Shah M, Fried VA, Etlinger JD, Sehgal PB.
    J Interferon Cytokine Res; 2002 May; 22(5):555-63. PubMed ID: 12060494
    [Abstract] [Full Text] [Related]

  • 24. Role of NADPH cytochrome P450 reductase in activation of RH1.
    Begleiter A, Leith MK, Patel D, Hasinoff BB.
    Cancer Chemother Pharmacol; 2007 Oct; 60(5):713-23. PubMed ID: 17256129
    [Abstract] [Full Text] [Related]

  • 25. Interactions of mitomycin C with mammalian DNA detected by alkaline elution.
    Dorr RT, Bowden GT, Alberts DS, Liddil JD.
    Cancer Res; 1985 Aug; 45(8):3510-6. PubMed ID: 3926301
    [Abstract] [Full Text] [Related]

  • 26. Characterization of a set of Chinese hamster ovary variant cell lines demonstrating differing sensitivity to mitomycin C.
    Kuehl BL, Buchwald M, Rauth AM.
    Oncol Res; 1993 Aug; 5(6-7):213-21. PubMed ID: 8123941
    [Abstract] [Full Text] [Related]

  • 27. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under hypoxia.
    Begleiter A, Robotham E, Leith MK.
    Mol Pharmacol; 1992 Apr; 41(4):677-82. PubMed ID: 1373799
    [Abstract] [Full Text] [Related]

  • 28. The NAD(P)H:quinone oxidoreductase locus in human colon carcinoma HCT 116 cells resistant to mitomycin C.
    Hu LT, Stamberg J, Pan S.
    Cancer Res; 1996 Nov 15; 56(22):5253-9. PubMed ID: 8912865
    [Abstract] [Full Text] [Related]

  • 29. Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells.
    Baumann RP, Hodnick WF, Seow HA, Belcourt MF, Rockwell S, Sherman DH, Sartorelli AC.
    Cancer Res; 2001 Nov 01; 61(21):7770-6. PubMed ID: 11691791
    [Abstract] [Full Text] [Related]

  • 30. NAD(P)H:Quinone oxidoreductase-1 C609T polymorphism analysis in human superficial bladder cancers: relationship of genotype status to NQO1 phenotype and clinical response to Mitomycin C.
    Basu S, Brown JE, Flannigan GM, Gill JH, Loadman PM, Martin SW, Naylor B, Puri R, Scally AJ, Seargent JM, Shah T, Phillips RM.
    Int J Oncol; 2004 Oct 01; 25(4):921-7. PubMed ID: 15375541
    [Abstract] [Full Text] [Related]

  • 31. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases.
    Beall HD, Mulcahy RT, Siegel D, Traver RD, Gibson NW, Ross D.
    Cancer Res; 1994 Jun 15; 54(12):3196-201. PubMed ID: 8205540
    [Abstract] [Full Text] [Related]

  • 32. RH1 induces cellular damage in an NAD(P)H:quinone oxidoreductase 1-dependent manner: relationship between DNA cross-linking, cell cycle perturbations, and apoptosis.
    Dehn DL, Inayat-Hussain SH, Ross D.
    J Pharmacol Exp Ther; 2005 May 15; 313(2):771-9. PubMed ID: 15665137
    [Abstract] [Full Text] [Related]

  • 33. Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D, Gibson NW, Preusch PC, Ross D.
    Cancer Res; 1990 Dec 01; 50(23):7483-9. PubMed ID: 1701346
    [Abstract] [Full Text] [Related]

  • 34. Genetic variation of human cytochrome p450 reductase as a potential biomarker for mitomycin C-induced cytotoxicity.
    Wang SL, Han JF, He XY, Wang XR, Hong JY.
    Drug Metab Dispos; 2007 Jan 01; 35(1):176-9. PubMed ID: 17062779
    [Abstract] [Full Text] [Related]

  • 35. The importance of DT-diaphorase in mitomycin C resistance in human colon cancer cell lines.
    Lambert PA, Kang Y, Greaves B, Perry RR.
    J Surg Res; 1998 Dec 01; 80(2):177-81. PubMed ID: 9878310
    [Abstract] [Full Text] [Related]

  • 36. Potentiation of apoptosis by flavopiridol in mitomycin-C-treated gastric and breast cancer cells.
    Schwartz GK, Farsi K, Maslak P, Kelsen DP, Spriggs D.
    Clin Cancer Res; 1997 Sep 01; 3(9):1467-72. PubMed ID: 9815832
    [Abstract] [Full Text] [Related]

  • 37. Tailoring targeted therapy to individual patients: lessons to be learnt from the development of mitomycin C.
    Volpato M, Phillips RM.
    Cancer Genomics Proteomics; 2007 Sep 01; 4(3):175-86. PubMed ID: 17878521
    [Abstract] [Full Text] [Related]

  • 38. Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase.
    Wang X, Doherty GP, Leith MK, Curphey TJ, Begleiter A.
    Br J Cancer; 1999 Jun 01; 80(8):1223-30. PubMed ID: 10376975
    [Abstract] [Full Text] [Related]

  • 39. NAD(P)H:quinone oxidoreductase1 (DT-diaphorase): expression, regulation, and role in cancer.
    Joseph P, Xie T, Xu Y, Jaiswal AK.
    Oncol Res; 1994 Jun 01; 6(10-11):525-32. PubMed ID: 7620221
    [Abstract] [Full Text] [Related]

  • 40. Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells.
    Fracasso PM, Sartorelli AC.
    Cancer Res; 1986 Aug 01; 46(8):3939-44. PubMed ID: 3089583
    [Abstract] [Full Text] [Related]

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