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786 related items for PubMed ID: 14522966

  • 1. Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.
    Park MT, Choi JA, Kim MJ, Um HD, Bae S, Kang CM, Cho CK, Kang S, Chung HY, Lee YS, Lee SJ.
    J Biol Chem; 2003 Dec 12; 278(50):50624-34. PubMed ID: 14522966
    [Abstract] [Full Text] [Related]

  • 2. Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells.
    Park MT, Kang JA, Choi JA, Kang CM, Kim TH, Bae S, Kang S, Kim S, Choi WI, Cho CK, Chung HY, Lee YS, Lee SJ.
    Clin Cancer Res; 2003 Feb 12; 9(2):878-85. PubMed ID: 12576463
    [Abstract] [Full Text] [Related]

  • 3. Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells.
    Nakagami H, Morishita R, Yamamoto K, Yoshimura SI, Taniyama Y, Aoki M, Matsubara H, Kim S, Kaneda Y, Ogihara T.
    Diabetes; 2001 Jun 12; 50(6):1472-81. PubMed ID: 11375350
    [Abstract] [Full Text] [Related]

  • 4. Sequence-dependent potentiation of paclitaxel-mediated apoptosis in human leukemia cells by inhibitors of the mitogen-activated protein kinase kinase/mitogen-activated protein kinase pathway.
    Yu C, Wang S, Dent P, Grant S.
    Mol Pharmacol; 2001 Jul 12; 60(1):143-54. PubMed ID: 11408609
    [Abstract] [Full Text] [Related]

  • 5. p38 Mitogen-activated protein kinase regulates Bax translocation in cyanide-induced apoptosis.
    Shou Y, Li L, Prabhakaran K, Borowitz JL, Isom GE.
    Toxicol Sci; 2003 Sep 12; 75(1):99-107. PubMed ID: 12805646
    [Abstract] [Full Text] [Related]

  • 6. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
    Söderström TS, Poukkula M, Holmström TH, Heiskanen KM, Eriksson JE.
    J Immunol; 2002 Sep 15; 169(6):2851-60. PubMed ID: 12218097
    [Abstract] [Full Text] [Related]

  • 7. Hepatocyte growth factor protects against hypoxia/reoxygenation-induced apoptosis in endothelial cells.
    Wang X, Zhou Y, Kim HP, Song R, Zarnegar R, Ryter SW, Choi AM.
    J Biol Chem; 2004 Feb 13; 279(7):5237-43. PubMed ID: 14625309
    [Abstract] [Full Text] [Related]

  • 8. Translocation and oligomerization of Bax is regulated independently by activation of p38 MAPK and caspase-2 during MN9D dopaminergic neurodegeneration.
    Oh CK, Han BS, Choi WS, Youdim MB, Oh YJ.
    Apoptosis; 2011 Nov 13; 16(11):1087-100. PubMed ID: 21739275
    [Abstract] [Full Text] [Related]

  • 9. Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells.
    Choi SY, Kim MJ, Kang CM, Bae S, Cho CK, Soh JW, Kim JH, Kang S, Chung HY, Lee YS, Lee SJ.
    J Biol Chem; 2006 Mar 17; 281(11):7049-59. PubMed ID: 16410245
    [Abstract] [Full Text] [Related]

  • 10. [The role of mitogen-activated protein kinase cascades in inhibition of proliferation in human prostate carcinoma cells by raloxifene: an in vitro experiment].
    Zhang YX, Kong CZ.
    Zhonghua Yi Xue Za Zhi; 2008 Jan 22; 88(4):271-5. PubMed ID: 18361842
    [Abstract] [Full Text] [Related]

  • 11. Combined action of extracellular signal-regulated kinase and p38 kinase rescues Molt4 T cells from nitric oxide-induced apoptotic and necrotic cell death.
    Oh HM, Choi SC, Lee HS, Chun CH, Seo GS, Choi EY, Lee HJ, Lee MS, Yeom JJ, Choi SJ, Han WC, Oh JM, Chung YT, Chun JS, Lee KM, Jun CD.
    Free Radic Biol Med; 2004 Aug 15; 37(4):463-79. PubMed ID: 15256218
    [Abstract] [Full Text] [Related]

  • 12. Induction of microsomal epoxide hydrolase by sulfur amino acid deprivation via the pathway of C-Jun N-terminal kinase and its extracellular exposure during cell death.
    Kang KW, Novak RF, Lee CH, Kim SG.
    Free Radic Biol Med; 2002 May 15; 32(10):1017-32. PubMed ID: 12008117
    [Abstract] [Full Text] [Related]

  • 13. Cilostazol protects endothelial cells against lipopolysaccharide-induced apoptosis through ERK1/2- and P38 MAPK-dependent pathways.
    Lim JH, Woo JS, Shin YW.
    Korean J Intern Med; 2009 Jun 15; 24(2):113-22. PubMed ID: 19543489
    [Abstract] [Full Text] [Related]

  • 14. Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways.
    Choi JA, Park MT, Kang CM, Um HD, Bae S, Lee KH, Kim TH, Kim JH, Cho CK, Lee YS, Chung HY, Lee SJ.
    Oncogene; 2004 Jan 08; 23(1):9-20. PubMed ID: 14712206
    [Abstract] [Full Text] [Related]

  • 15. Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95- and mitochondrial-mediated mechanism.
    Gajate C, An F, Mollinedo F.
    Clin Cancer Res; 2003 Apr 08; 9(4):1535-45. PubMed ID: 12684430
    [Abstract] [Full Text] [Related]

  • 16. Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and suppression of ERK1/2 MAPK in HeLa cells.
    Li Y, Lu X, Qi H, Li X, Xiao X, Gao J.
    J Pharmacol Sci; 2014 Apr 08; 125(2):202-10. PubMed ID: 24881958
    [Abstract] [Full Text] [Related]

  • 17. Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes.
    Van Laethem A, Van Kelst S, Lippens S, Declercq W, Vandenabeele P, Janssens S, Vandenheede JR, Garmyn M, Agostinis P.
    FASEB J; 2004 Dec 08; 18(15):1946-8. PubMed ID: 15388671
    [Abstract] [Full Text] [Related]

  • 18. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
    Cheong JW, Chong SY, Kim JY, Eom JI, Jeung HK, Maeng HY, Lee ST, Min YH.
    Clin Cancer Res; 2003 Oct 15; 9(13):5018-27. PubMed ID: 14581377
    [Abstract] [Full Text] [Related]

  • 19. Ultraviolet A-induced modulation of Bcl-XL by p38 MAPK in human keratinocytes: post-transcriptional regulation through the 3'-untranslated region.
    Bachelor MA, Bowden GT.
    J Biol Chem; 2004 Oct 08; 279(41):42658-68. PubMed ID: 15292226
    [Abstract] [Full Text] [Related]

  • 20. Cyclic AMP promotes cAMP-responsive element-binding protein-dependent induction of cellular inhibitor of apoptosis protein-2 and suppresses apoptosis of colon cancer cells through ERK1/2 and p38 MAPK.
    Nishihara H, Hwang M, Kizaka-Kondoh S, Eckmann L, Insel PA.
    J Biol Chem; 2004 Jun 18; 279(25):26176-83. PubMed ID: 15078890
    [Abstract] [Full Text] [Related]

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