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Journal Abstract Search

294 related items for PubMed ID: 14523228

  • 1. Thrombomodulin allosterically modulates the activity of the anticoagulant thrombin.
    Rezaie AR, Yang L.
    Proc Natl Acad Sci U S A; 2003 Oct 14; 100(21):12051-6. PubMed ID: 14523228
    [Abstract] [Full Text] [Related]

  • 2. Probing the activation of protein C by the thrombin-thrombomodulin complex using structural analysis, site-directed mutagenesis, and computer modeling.
    Knobe KE, Berntsdotter A, Shen L, Morser J, Dahlbäck B, Villoutreix BO.
    Proteins; 1999 May 01; 35(2):218-34. PubMed ID: 10223294
    [Abstract] [Full Text] [Related]

  • 3. Activation of protein C by the thrombin-thrombomodulin complex: cooperative roles of Arg-35 of thrombin and Arg-67 of protein C.
    Yang L, Manithody C, Rezaie AR.
    Proc Natl Acad Sci U S A; 2006 Jan 24; 103(4):879-84. PubMed ID: 16418283
    [Abstract] [Full Text] [Related]

  • 4. Mutagenesis studies toward understanding the mechanism of the cofactor function of thrombomodulin.
    Rezaie AR, Yang L.
    Biophys Chem; 2005 Oct 03; 117(3):255-61. PubMed ID: 15970373
    [Abstract] [Full Text] [Related]

  • 5. Mutagenesis studies toward understanding allostery in thrombin.
    Qureshi SH, Yang L, Manithody C, Iakhiaev AV, Rezaie AR.
    Biochemistry; 2009 Sep 01; 48(34):8261-70. PubMed ID: 19640005
    [Abstract] [Full Text] [Related]

  • 6. Role of Leu99 of thrombin in determining the P2 specificity of serpins.
    Rezaie AR.
    Biochemistry; 1997 Jun 17; 36(24):7437-46. PubMed ID: 9200692
    [Abstract] [Full Text] [Related]

  • 7. Thrombin interacts with thrombomodulin, protein C, and thrombin-activatable fibrinolysis inhibitor via specific and distinct domains.
    Hall SW, Nagashima M, Zhao L, Morser J, Leung LL.
    J Biol Chem; 1999 Sep 03; 274(36):25510-6. PubMed ID: 10464282
    [Abstract] [Full Text] [Related]

  • 8. The roles of selected arginine and lysine residues of TAFI (Pro-CPU) in its activation to TAFIa by the thrombin-thrombomodulin complex.
    Wu C, Kim PY, Manuel R, Seto M, Whitlow M, Nagashima M, Morser J, Gils A, Declerck P, Nesheim ME.
    J Biol Chem; 2009 Mar 13; 284(11):7059-67. PubMed ID: 19074424
    [Abstract] [Full Text] [Related]

  • 9. Essential thrombin residues for inhibition by protein C inhibitor with the cofactors heparin and thrombomodulin.
    Fortenberry YM, Whinna HC, Cooper ST, Myles T, Leung LL, Church FC.
    J Thromb Haemost; 2007 Jul 13; 5(7):1486-92. PubMed ID: 17635698
    [Abstract] [Full Text] [Related]

  • 10. Thrombomodulin Binding Selects the Catalytically Active Form of Thrombin.
    Handley LD, Treuheit NA, Venkatesh VJ, Komives EA.
    Biochemistry; 2015 Nov 03; 54(43):6650-8. PubMed ID: 26468766
    [Abstract] [Full Text] [Related]

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  • 12. Role of Gly197 in the structure and function of protein C.
    Lu Y, Biswas I, Villoutreix BO, Rezaie AR.
    Biochim Biophys Acta Gen Subj; 2021 Jun 03; 1865(6):129892. PubMed ID: 33722640
    [Abstract] [Full Text] [Related]

  • 13. The affinity of protein C for the thrombin.thrombomodulin complex is determined in a primary way by active site-dependent interactions.
    Lu G, Chhum S, Krishnaswamy S.
    J Biol Chem; 2005 Apr 15; 280(15):15471-8. PubMed ID: 15705565
    [Abstract] [Full Text] [Related]

  • 14. Lys 42/43/44 and Arg 12 of thrombin-activable fibrinolysis inhibitor comprise a thrombomodulin exosite essential for its antifibrinolytic potential.
    Wu C, Stafford AR, Fredenburgh JC, Weitz JI, Gils A, Declerck PJ, Kim PY.
    Thromb Haemost; 2017 Jul 26; 117(8):1509-1517. PubMed ID: 28640323
    [Abstract] [Full Text] [Related]

  • 15. Occupancy of anion binding exosite 2 on thrombin determines Ca2+ dependence of protein C activation.
    Liu LW, Rezaie AR, Carson CW, Esmon NL, Esmon CT.
    J Biol Chem; 1994 Apr 22; 269(16):11807-12. PubMed ID: 8163479
    [Abstract] [Full Text] [Related]

  • 16. Role of exosites 1 and 2 in thrombin reaction with plasminogen activator inhibitor-1 in the absence and presence of cofactors.
    Rezaie AR.
    Biochemistry; 1999 Nov 02; 38(44):14592-9. PubMed ID: 10545182
    [Abstract] [Full Text] [Related]

  • 17. The thrombin epitope recognizing thrombomodulin is a highly cooperative hot spot in exosite I.
    Pineda AO, Cantwell AM, Bush LA, Rose T, Di Cera E.
    J Biol Chem; 2002 Aug 30; 277(35):32015-9. PubMed ID: 12068020
    [Abstract] [Full Text] [Related]

  • 18. The fourth epidermal growth factor-like domain of thrombomodulin interacts with the basic exosite of protein C.
    Yang L, Rezaie AR.
    J Biol Chem; 2003 Mar 21; 278(12):10484-90. PubMed ID: 12529320
    [Abstract] [Full Text] [Related]

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  • 20. Calcium-binding sites of the thrombin-thrombomodulin-protein C complex: possible implications for the effect of platelet factor 4 on the activation of vitamin K-dependent coagulation factors.
    Yang L, Rezaie AR.
    Thromb Haemost; 2007 Jun 21; 97(6):899-906. PubMed ID: 17549291
    [Abstract] [Full Text] [Related]

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