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221 related items for PubMed ID: 14525948

  • 1. Abnormal PTEN expression in portal hypertensive gastric mucosa: a key to impaired PI 3-kinase/Akt activation and delayed injury healing?
    Tsugawa K, Jones MK, Akahoshi T, Moon WS, Maehara Y, Hashizume M, Sarfeh IJ, Tarnawski AS.
    FASEB J; 2003 Dec; 17(15):2316-8. PubMed ID: 14525948
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  • 2. Activation of eNOS in rat portal hypertensive gastric mucosa is mediated by TNF-alpha via the PI 3-kinase-Akt signaling pathway.
    Kawanaka H, Jones MK, Szabo IL, Baatar D, Pai R, Tsugawa K, Sugimachi K, Sarfeh IJ, Tarnawski AS.
    Hepatology; 2002 Feb; 35(2):393-402. PubMed ID: 11826414
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  • 6. PTEN permits acute increases in D3-phosphoinositide levels following TCR stimulation but inhibits distal signaling events by reducing the basal activity of Akt.
    Seminario MC, Precht P, Bunnell SC, Warren SE, Morris CM, Taub D, Wange RL.
    Eur J Immunol; 2004 Nov; 34(11):3165-75. PubMed ID: 15468057
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  • 8. The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells.
    Asano T, Yao Y, Zhu J, Li D, Abbruzzese JL, Reddy SA.
    Oncogene; 2004 Nov 11; 23(53):8571-80. PubMed ID: 15467756
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  • 9. Despite activation of EGF-receptor-ERK signaling pathway, epithelial proliferation is impaired in portal hypertensive gastric mucosa: relevance of MKP-1, c-fos, c-myc, and cyclin D1 expression.
    Kawanaka H, Tomikawa M, Baatar D, Jones MK, Pai R, Szabo IL, Sugimachi K, Sarfeh IJ, Tarnawski AS.
    Life Sci; 2001 Nov 09; 69(25-26):3019-33. PubMed ID: 11758828
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  • 14. Defective mitogen-activated protein kinase (ERK2) signaling in gastric mucosa of portal hypertensive rats: potential therapeutic implications.
    Kawanaka H, Tomikawa M, Jones MK, Szabo IL, Pai R, Baatar D, Tsugawa K, Sugimachi K, Sarfeh IJ, Tarnawski AS.
    Hepatology; 2001 Nov 09; 34(5):990-9. PubMed ID: 11679970
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  • 15. Cilostazol prevents tumor necrosis factor-alpha-induced cell death by suppression of phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and activation of Akt/cyclic AMP response element-binding protein phosphorylation.
    Hong KW, Kim KY, Shin HK, Lee JH, Choi JM, Kwak YG, Kim CD, Lee WS, Rhim BY.
    J Pharmacol Exp Ther; 2003 Sep 09; 306(3):1182-90. PubMed ID: 12807996
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  • 16. Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop.
    Kim S, Domon-Dell C, Kang J, Chung DH, Freund JN, Evers BM.
    J Biol Chem; 2004 Feb 06; 279(6):4285-91. PubMed ID: 14623898
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  • 17. Aging gastropathy-novel mechanisms: hypoxia, up-regulation of multifunctional phosphatase PTEN, and proapoptotic factors.
    Tarnawski A, Pai R, Deng X, Ahluwalia A, Khomenko T, Tanigawa T, Akahoshi T, Sandor Z, Szabo S.
    Gastroenterology; 2007 Dec 06; 133(6):1938-47. PubMed ID: 18054565
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  • 18. Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.
    Lu Y, Yu Q, Liu JH, Zhang J, Wang H, Koul D, McMurray JS, Fang X, Yung WK, Siminovitch KA, Mills GB.
    J Biol Chem; 2003 Oct 10; 278(41):40057-66. PubMed ID: 12869565
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  • 19. Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes.
    Ono H, Katagiri H, Funaki M, Anai M, Inukai K, Fukushima Y, Sakoda H, Ogihara T, Onishi Y, Fujishiro M, Kikuchi M, Oka Y, Asano T.
    Mol Endocrinol; 2001 Aug 10; 15(8):1411-22. PubMed ID: 11463863
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  • 20. Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway.
    Zhang J, Choi Y, Mavromatis B, Lichtenstein A, Li W.
    Oncogene; 2003 Sep 18; 22(40):6289-95. PubMed ID: 13679867
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