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Journal Abstract Search

218 related items for PubMed ID: 14525990

  • 1. Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor.
    Absalom NL, Lewis TM, Kaplan W, Pierce KD, Schofield PR.
    J Biol Chem; 2003 Dec 12; 278(50):50151-7. PubMed ID: 14525990
    [Abstract] [Full Text] [Related]

  • 2. A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor.
    Schofield CM, Jenkins A, Harrison NL.
    J Biol Chem; 2003 Sep 05; 278(36):34079-83. PubMed ID: 12826676
    [Abstract] [Full Text] [Related]

  • 3. Comparison of taurine- and glycine-induced conformational changes in the M2-M3 domain of the glycine receptor.
    Han NL, Clements JD, Lynch JW.
    J Biol Chem; 2004 May 07; 279(19):19559-65. PubMed ID: 14981077
    [Abstract] [Full Text] [Related]

  • 4. A picrotoxin-specific conformational change in the glycine receptor M2-M3 loop.
    Hawthorne R, Lynch JW.
    J Biol Chem; 2005 Oct 28; 280(43):35836-43. PubMed ID: 16109711
    [Abstract] [Full Text] [Related]

  • 5. A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors.
    Xiu X, Hanek AP, Wang J, Lester HA, Dougherty DA.
    J Biol Chem; 2005 Dec 16; 280(50):41655-66. PubMed ID: 16216879
    [Abstract] [Full Text] [Related]

  • 6. Conformational changes in extracellular loop 2 associated with signal transduction in the glycine receptor.
    Cederholm JM, Absalom NL, Sugiharto S, Griffith R, Schofield PR, Lewis TM.
    J Neurochem; 2010 Dec 16; 115(5):1245-55. PubMed ID: 20874766
    [Abstract] [Full Text] [Related]

  • 7. The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state.
    Lynch JW, Han NL, Haddrill J, Pierce KD, Schofield PR.
    J Neurosci; 2001 Apr 15; 21(8):2589-99. PubMed ID: 11306612
    [Abstract] [Full Text] [Related]

  • 8. Correlating structural and energetic changes in glycine receptor activation.
    Scott S, Lynch JW, Keramidas A.
    J Biol Chem; 2015 Feb 27; 290(9):5621-34. PubMed ID: 25572390
    [Abstract] [Full Text] [Related]

  • 9. Contributions of conserved residues at the gating interface of glycine receptors.
    Pless SA, Leung AW, Galpin JD, Ahern CA.
    J Biol Chem; 2011 Oct 07; 286(40):35129-36. PubMed ID: 21835920
    [Abstract] [Full Text] [Related]

  • 10. Predicted structure of the extracellular region of ligand-gated ion-channel receptors shows SH2-like and SH3-like domains forming the ligand-binding site.
    Gready JE, Ranganathan S, Schofield PR, Matsuo Y, Nishikawa K.
    Protein Sci; 1997 May 07; 6(5):983-98. PubMed ID: 9144769
    [Abstract] [Full Text] [Related]

  • 11. The Cys-loop superfamily of ligand-gated ion channels: the impact of receptor structure on function.
    Connolly CN, Wafford KA.
    Biochem Soc Trans; 2004 Jun 07; 32(Pt3):529-34. PubMed ID: 15157178
    [Abstract] [Full Text] [Related]

  • 12. Analysis of the third transmembrane domain of the human type 1 angiotensin II receptor by cysteine scanning mutagenesis.
    Martin SS, Boucard AA, Clément M, Escher E, Leduc R, Guillemette G.
    J Biol Chem; 2004 Dec 03; 279(49):51415-23. PubMed ID: 15452107
    [Abstract] [Full Text] [Related]

  • 13. Channel gating of the glycine receptor changes accessibility to residues implicated in receptor potentiation by alcohols and anesthetics.
    Lobo IA, Mascia MP, Trudell JR, Harris RA.
    J Biol Chem; 2004 Aug 06; 279(32):33919-27. PubMed ID: 15169788
    [Abstract] [Full Text] [Related]

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  • 15. Coupling of agonist binding to channel gating in the GABA(A) receptor.
    Kash TL, Jenkins A, Kelley JC, Trudell JR, Harrison NL.
    Nature; 2003 Jan 16; 421(6920):272-5. PubMed ID: 12529644
    [Abstract] [Full Text] [Related]

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  • 17. Characterization of a glycine receptor domain that controls the binding and gating mechanisms of the beta-amino acid agonist, taurine.
    Han NL, Haddrill JL, Lynch JW.
    J Neurochem; 2001 Nov 16; 79(3):636-47. PubMed ID: 11701767
    [Abstract] [Full Text] [Related]

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  • 19. Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor.
    Wang Q, Lynch JW.
    J Biol Chem; 2011 Nov 04; 286(44):38814-38824. PubMed ID: 21917927
    [Abstract] [Full Text] [Related]

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