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125 related items for PubMed ID: 14530152

  • 1. Farnesyltransferase inhibitors as radiation sensitizers.
    Brunner TB, Gupta AK, Shi Y, Hahn SM, Muschel RJ, McKenna WG, Bernhard EJ.
    Int J Radiat Biol; 2003 Jul; 79(7):569-76. PubMed ID: 14530152
    [Abstract] [Full Text] [Related]

  • 2. Radiation sensitization by inhibition of activated Ras.
    Brunner TB, Hahn SM, McKenna WG, Bernhard EJ.
    Strahlenther Onkol; 2004 Nov; 180(11):731-40. PubMed ID: 15549191
    [Abstract] [Full Text] [Related]

  • 3. Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2.
    Alcock RA, Dey S, Chendil D, Inayat MS, Mohiuddin M, Hartman G, Chatfield LK, Gallicchio VS, Ahmed MM.
    Oncogene; 2002 Nov 07; 21(51):7883-90. PubMed ID: 12420225
    [Abstract] [Full Text] [Related]

  • 4. Farnesyltransferase inhibitors as radiation sensitizers.
    McKenna WG, Muschel RJ, Gupta AK, Hahn SM, Bernhard EJ.
    Semin Radiat Oncol; 2002 Jul 07; 12(3 Suppl 2):27-32. PubMed ID: 12174342
    [Abstract] [Full Text] [Related]

  • 5. Farnesyltransferase inhibitor effects on prostate tumor micro-environment and radiation survival.
    Shi Y, Wu J, Mick R, Cerniglia GJ, Cohen-Jonathan E, Rhim JS, Koch CJ, Bernhard EJ.
    Prostate; 2005 Jan 01; 62(1):69-82. PubMed ID: 15389805
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  • 8. Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras.
    Brunner TB, Cengel KA, Hahn SM, Wu J, Fraker DL, McKenna WG, Bernhard EJ.
    Cancer Res; 2005 Sep 15; 65(18):8433-41. PubMed ID: 16166322
    [Abstract] [Full Text] [Related]

  • 9. Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.
    Lobell RB, Omer CA, Abrams MT, Bhimnathwala HG, Brucker MJ, Buser CA, Davide JP, deSolms SJ, Dinsmore CJ, Ellis-Hutchings MS, Kral AM, Liu D, Lumma WC, Machotka SV, Rands E, Williams TM, Graham SL, Hartman GD, Oliff AI, Heimbrook DC, Kohl NE.
    Cancer Res; 2001 Dec 15; 61(24):8758-68. PubMed ID: 11751396
    [Abstract] [Full Text] [Related]

  • 10. Combining prenylation inhibitors causes synergistic cytotoxicity, apoptosis and disruption of RAS-to-MAP kinase signalling in multiple myeloma cells.
    Morgan MA, Sebil T, Aydilek E, Peest D, Ganser A, Reuter CW.
    Br J Haematol; 2005 Sep 15; 130(6):912-25. PubMed ID: 16156861
    [Abstract] [Full Text] [Related]

  • 11. RhoB controls the 24 kDa FGF-2-induced radioresistance in HeLa cells by preventing post-mitotic cell death.
    Ader I, Toulas C, Dalenc F, Delmas C, Bonnet J, Cohen-Jonathan E, Favre G.
    Oncogene; 2002 Sep 05; 21(39):5998-6006. PubMed ID: 12203112
    [Abstract] [Full Text] [Related]

  • 12. Signaling inhibition with radiation in colorectal cancer: clinical trials.
    McKenna WG, Muschel RJ, Gupta A, Hahn S, Bernhard EJ.
    Semin Oncol; 2003 Jun 05; 30(3 Suppl 6):56-67. PubMed ID: 12802796
    [Abstract] [Full Text] [Related]

  • 13. The farnesyl transferase inhibitor, FTI-277, inhibits growth and induces apoptosis in drug-resistant myeloma tumor cells.
    Bolick SC, Landowski TH, Boulware D, Oshiro MM, Ohkanda J, Hamilton AD, Sebti SM, Dalton WS.
    Leukemia; 2003 Feb 05; 17(2):451-7. PubMed ID: 12592346
    [Abstract] [Full Text] [Related]

  • 14. In vitro study of farnesyltransferase inhibitor SCH 66336, in combination with chemotherapy and radiation, in non-small cell lung cancer cell lines.
    Loprevite M, Favoni RE, De Cupis A, Scolaro T, Semino C, Mazzanti P, Ardizzoni A.
    Oncol Rep; 2004 Feb 05; 11(2):407-14. PubMed ID: 14719076
    [Abstract] [Full Text] [Related]

  • 15. The farnesyltransferase inhibitor FTI-277 radiosensitizes H-ras-transformed rat embryo fibroblasts.
    Bernhard EJ, Kao G, Cox AD, Sebti SM, Hamilton AD, Muschel RJ, McKenna WG.
    Cancer Res; 1996 Apr 15; 56(8):1727-30. PubMed ID: 8620483
    [Abstract] [Full Text] [Related]

  • 16. Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation.
    Delmas C, Heliez C, Cohen-Jonathan E, End D, Bonnet J, Favre G, Toulas C.
    Int J Cancer; 2002 Jul 01; 100(1):43-8. PubMed ID: 12115585
    [Abstract] [Full Text] [Related]

  • 17. A Phase I trial of the farnesyltransferase inhibitor L-778,123 and radiotherapy for locally advanced lung and head and neck cancer.
    Hahn SM, Bernhard EJ, Regine W, Mohiuddin M, Haller DG, Stevenson JP, Smith D, Pramanik B, Tepper J, DeLaney TF, Kiel KD, Morrison B, Deutsch P, Muschel RJ, McKenna WG.
    Clin Cancer Res; 2002 May 01; 8(5):1065-72. PubMed ID: 12006520
    [Abstract] [Full Text] [Related]

  • 18. Therapeutic targets in radiotherapy.
    Brown JM.
    Int J Radiat Oncol Biol Phys; 2001 Feb 01; 49(2):319-26. PubMed ID: 11173124
    [Abstract] [Full Text] [Related]

  • 19. Growth inhibition of astrocytoma cells by farnesyl transferase inhibitors is mediated by a combination of anti-proliferative, pro-apoptotic and anti-angiogenic effects.
    Feldkamp MM, Lau N, Guha A.
    Oncogene; 1999 Dec 09; 18(52):7514-26. PubMed ID: 10602510
    [Abstract] [Full Text] [Related]

  • 20. Farnesyltransferase inhibitors: potential role in the treatment of cancer.
    Cox AD.
    Drugs; 2001 Dec 09; 61(6):723-32. PubMed ID: 11398905
    [Abstract] [Full Text] [Related]

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