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Journal Abstract Search

265 related items for PubMed ID: 14555609

  • 1. Evaluation of the cancer chemopreventive potency of dithiolethione analogs of oltipraz.
    Roebuck BD, Curphey TJ, Li Y, Baumgartner KJ, Bodreddigari S, Yan J, Gange SJ, Kensler TW, Sutter TR.
    Carcinogenesis; 2003 Dec; 24(12):1919-28. PubMed ID: 14555609
    [Abstract] [Full Text] [Related]

  • 2. Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones.
    Kensler TW, Egner PA, Dolan PM, Groopman JD, Roebuck BD.
    Cancer Res; 1987 Aug 15; 47(16):4271-7. PubMed ID: 2886217
    [Abstract] [Full Text] [Related]

  • 3. Transient intervention with oltipraz protects against aflatoxin-induced hepatic tumorigenesis.
    Bolton MG, Muñoz A, Jacobson LP, Groopman JD, Maxuitenko YY, Roebuck BD, Kensler TW.
    Cancer Res; 1993 Aug 01; 53(15):3499-504. PubMed ID: 8339253
    [Abstract] [Full Text] [Related]

  • 4. Intermittent dosing with oltipraz: relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases.
    Primiano T, Egner PA, Sutter TR, Kelloff GJ, Roebuck BD, Kensler TW.
    Cancer Res; 1995 Oct 01; 55(19):4319-24. PubMed ID: 7671242
    [Abstract] [Full Text] [Related]

  • 5. Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.
    Yates MS, Kwak MK, Egner PA, Groopman JD, Bodreddigari S, Sutter TR, Baumgartner KJ, Roebuck BD, Liby KT, Yore MM, Honda T, Gribble GW, Sporn MB, Kensler TW.
    Cancer Res; 2006 Feb 15; 66(4):2488-94. PubMed ID: 16489057
    [Abstract] [Full Text] [Related]

  • 6. Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.
    Kwak MK, Itoh K, Yamamoto M, Sutter TR, Kensler TW.
    Mol Med; 2001 Feb 15; 7(2):135-45. PubMed ID: 11471548
    [Abstract] [Full Text] [Related]

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  • 8. Protection conferred by selenium deficiency against aflatoxin B1 in the rat is associated with the hepatic expression of an aldo-keto reductase and a glutathione S-transferase subunit that metabolize the mycotoxin.
    McLeod R, Ellis EM, Arthur JR, Neal GE, Judah DJ, Manson MM, Hayes JD.
    Cancer Res; 1997 Oct 01; 57(19):4257-66. PubMed ID: 9331086
    [Abstract] [Full Text] [Related]

  • 9. Identification of dithiolethiones with better chemopreventive properties than oltipraz.
    Maxuitenko YY, Libby AH, Joyner HH, Curphey TJ, MacMillan DL, Kensler TW, Roebuck BD.
    Carcinogenesis; 1998 Sep 01; 19(9):1609-15. PubMed ID: 9771932
    [Abstract] [Full Text] [Related]

  • 10. Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione.
    Kensler TW, Groopman JD, Eaton DL, Curphey TJ, Roebuck BD.
    Carcinogenesis; 1992 Jan 01; 13(1):95-100. PubMed ID: 1346373
    [Abstract] [Full Text] [Related]

  • 11. Cellular kinetics of induction by oltipraz and its keto derivative of detoxication enzymes in human colon adenocarcinoma cells.
    O'Dwyer PJ, Clayton M, Halbherr T, Myers CB, Yao Ks.
    Clin Cancer Res; 1997 May 01; 3(5):783-91. PubMed ID: 9815750
    [Abstract] [Full Text] [Related]

  • 12. Predictive value of molecular dosimetry: individual versus group effects of oltipraz on aflatoxin-albumin adducts and risk of liver cancer.
    Kensler TW, Gange SJ, Egner PA, Dolan PM, Muñoz A, Groopman JD, Rogers AE, Roebuck BD.
    Cancer Epidemiol Biomarkers Prev; 1997 Aug 01; 6(8):603-10. PubMed ID: 9264273
    [Abstract] [Full Text] [Related]

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  • 14. Induction of DT-diaphorase in cancer chemoprevention and chemotherapy.
    Begleiter A, Leith MK, Curphey TJ, Doherty GP.
    Oncol Res; 1997 Aug 01; 9(6-7):371-82. PubMed ID: 9406243
    [Abstract] [Full Text] [Related]

  • 15. Resistance to aflatoxin B1 is associated with the expression of a novel aldo-keto reductase which has catalytic activity towards a cytotoxic aldehyde-containing metabolite of the toxin.
    Hayes JD, Judah DJ, Neal GE.
    Cancer Res; 1993 Sep 01; 53(17):3887-94. PubMed ID: 8395332
    [Abstract] [Full Text] [Related]

  • 16. Regulation of glutathione S-transferases and aldehyde reductase by chemoprotectors: studies of mechanisms responsible for inducible resistance to aflatoxin B1.
    Hayes JD, McLeod R, Ellis EM, Pulford DJ, Ireland LS, McLellan LI, Judah DJ, Manson MM, Neal GE.
    IARC Sci Publ; 1996 Sep 01; (139):175-87. PubMed ID: 8923030
    [Abstract] [Full Text] [Related]

  • 17. Indole-3-carbinol induces a rat liver glutathione transferase subunit (Yc2) with high activity toward aflatoxin B1 exo-epoxide. Association with reduced levels of hepatic aflatoxin-DNA adducts in vivo.
    Stresser DM, Williams DE, McLellan LI, Harris TM, Bailey GS.
    Drug Metab Dispos; 1994 Sep 01; 22(3):392-9. PubMed ID: 8070315
    [Abstract] [Full Text] [Related]

  • 18. Transcriptional control of glutathione S-transferase gene expression by the chemoprotective agent 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz) in rat liver.
    Davidson NE, Egner PA, Kensler TW.
    Cancer Res; 1990 Apr 15; 50(8):2251-5. PubMed ID: 2317812
    [Abstract] [Full Text] [Related]

  • 19. Role of phase 2 enzyme induction in chemoprotection by dithiolethiones.
    Kwak MK, Egner PA, Dolan PM, Ramos-Gomez M, Groopman JD, Itoh K, Yamamoto M, Kensler TW.
    Mutat Res; 2001 Sep 01; 480-481():305-15. PubMed ID: 11506823
    [Abstract] [Full Text] [Related]

  • 20. Chemoprevention by inducers of carcinogen detoxication enzymes.
    Kensler TW.
    Environ Health Perspect; 1997 Jun 01; 105 Suppl 4(Suppl 4):965-70. PubMed ID: 9255588
    [Abstract] [Full Text] [Related]

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