These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
23. Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials. Clément K, van den Akker E, Argente J, Bahm A, Chung WK, Connors H, De Waele K, Farooqi IS, Gonneau-Lejeune J, Gordon G, Kohlsdorf K, Poitou C, Puder L, Swain J, Stewart M, Yuan G, Wabitsch M, Kühnen P, Setmelanotide POMC and LEPR Phase 3 Trial Investigators. Lancet Diabetes Endocrinol; 2020 Dec; 8(12):960-970. PubMed ID: 33137293 [Abstract] [Full Text] [Related]
26. Systematic mutation screening of the pro-opiomelanocortin gene: identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes. Hinney A, Becker I, Heibült O, Nottebom K, Schmidt A, Ziegler A, Mayer H, Siegfried W, Blum WF, Remschmidt H, Hebebrand J. J Clin Endocrinol Metab; 1998 Oct; 83(10):3737-41. PubMed ID: 9768693 [Abstract] [Full Text] [Related]
30. Peripheral administration of the N-terminal pro-opiomelanocortin fragment 1-28 to Pomc-/- mice reduces food intake and weight but does not affect adrenal growth or corticosterone production. Coll AP, Fassnacht M, Klammer S, Hahner S, Schulte DM, Piper S, Tung YC, Challis BG, Weinstein Y, Allolio B, O'Rahilly S, Beuschlein F. J Endocrinol; 2006 Aug; 190(2):515-25. PubMed ID: 16899584 [Abstract] [Full Text] [Related]
31. Lack of red hair phenotype in a North-African obese child homozygous for a novel POMC null mutation: nonsense-mediated decay RNA evaluation and hair pigment chemical analysis. Cirillo G, Marini R, Ito S, Wakamatsu K, Scianguetta S, Bizzarri C, Romano A, Grandone A, Perrone L, Cappa M, Miraglia Del Giudice E. Br J Dermatol; 2012 Dec; 167(6):1393-5. PubMed ID: 22612534 [No Abstract] [Full Text] [Related]
36. Neuropeptide processing and its impact on melanocortin pathways. Pritchard LE, White A. Endocrinology; 2007 Sep; 148(9):4201-7. PubMed ID: 17584964 [Abstract] [Full Text] [Related]
37. Molecular screening of the proopiomelanocortin (POMC ) gene in Italian obese children: report of three new mutations. Miraglia del Giudice E, Cirillo G, Santoro N, D'Urso L, Carbone MT, Di Toro R, Perrone L. Int J Obes Relat Metab Disord; 2001 Jan; 25(1):61-7. PubMed ID: 11244459 [Abstract] [Full Text] [Related]