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210 related items for PubMed ID: 14559920

  • 1. AKT/protein kinase B regulation of BCL family members during oxysterol-induced apoptosis.
    Rusiñol AE, Thewke D, Liu J, Freeman N, Panini SR, Sinensky MS.
    J Biol Chem; 2004 Jan 09; 279(2):1392-9. PubMed ID: 14559920
    [Abstract] [Full Text] [Related]

  • 2. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
    Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ.
    Mol Cell; 2001 Sep 09; 8(3):705-11. PubMed ID: 11583631
    [Abstract] [Full Text] [Related]

  • 3. The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.
    Zhang XD, Gillespie SK, Borrow JM, Hersey P.
    Mol Cancer Ther; 2004 Apr 09; 3(4):425-35. PubMed ID: 15078986
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of phosphatidylinositol 3-kinase/AKT signaling by NVP-BKM120 promotes ABT-737-induced toxicity in a caspase-dependent manner through mitochondrial dysfunction and DNA damage response in established and primary cultured glioblastoma cells.
    Jane EP, Premkumar DR, Morales A, Foster KA, Pollack IF.
    J Pharmacol Exp Ther; 2014 Jul 09; 350(1):22-35. PubMed ID: 24741074
    [Abstract] [Full Text] [Related]

  • 5. Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin.
    Lim DY, Park JH.
    Am J Physiol Gastrointest Liver Physiol; 2009 May 09; 296(5):G1060-8. PubMed ID: 19264955
    [Abstract] [Full Text] [Related]

  • 6. Application of proteasomal inhibitors to mouse sympathetic neurons activates the intrinsic apoptotic pathway.
    Lang-Rollin I, Vekrellis K, Wang Q, Rideout HJ, Stefanis L.
    J Neurochem; 2004 Sep 09; 90(6):1511-20. PubMed ID: 15341534
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of PI3-kinase-Akt pathway enhances dexamethasone-induced apoptosis in a human follicular lymphoma cell line.
    Nuutinen U, Postila V, Mättö M, Eeva J, Ropponen A, Eray M, Riikonen P, Pelkonen J.
    Exp Cell Res; 2006 Feb 01; 312(3):322-30. PubMed ID: 16309671
    [Abstract] [Full Text] [Related]

  • 8. Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release.
    Sheridan C, Delivani P, Cullen SP, Martin SJ.
    Mol Cell; 2008 Aug 22; 31(4):570-585. PubMed ID: 18722181
    [Abstract] [Full Text] [Related]

  • 9. An interconnected hierarchical model of cell death regulation by the BCL-2 family.
    Chen HC, Kanai M, Inoue-Yamauchi A, Tu HC, Huang Y, Ren D, Kim H, Takeda S, Reyna DE, Chan PM, Ganesan YT, Liao CP, Gavathiotis E, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2015 Oct 22; 17(10):1270-81. PubMed ID: 26344567
    [Abstract] [Full Text] [Related]

  • 10. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2006 Dec 22; 8(12):1348-58. PubMed ID: 17115033
    [Abstract] [Full Text] [Related]

  • 11. ARF tumor suppressor induces mitochondria-dependent apoptosis by modulation of mitochondrial Bcl-2 family proteins.
    Nakazawa Y, Kamijo T, Koike K, Noda T.
    J Biol Chem; 2003 Jul 25; 278(30):27888-95. PubMed ID: 12740365
    [Abstract] [Full Text] [Related]

  • 12. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J, Huang K, O'Neill KL, Pang X, Luo X.
    Cell Death Dis; 2016 Jun 16; 7(6):e2266. PubMed ID: 27310874
    [Abstract] [Full Text] [Related]

  • 13. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells.
    Gillespie S, Borrow J, Zhang XD, Hersey P.
    Apoptosis; 2006 Dec 16; 11(12):2251-65. PubMed ID: 17051334
    [Abstract] [Full Text] [Related]

  • 14. Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent.
    Choi S, Singh SV.
    Cancer Res; 2005 Mar 01; 65(5):2035-43. PubMed ID: 15753404
    [Abstract] [Full Text] [Related]

  • 15. Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.
    Wang YF, Jiang CC, Kiejda KA, Gillespie S, Zhang XD, Hersey P.
    Clin Cancer Res; 2007 Aug 15; 13(16):4934-42. PubMed ID: 17652623
    [Abstract] [Full Text] [Related]

  • 16. Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax.
    Panaretakis T, Pokrovskaja K, Shoshan MC, Grandér D.
    Oncogene; 2003 Jul 17; 22(29):4543-56. PubMed ID: 12881711
    [Abstract] [Full Text] [Related]

  • 17. Bim(L) displacing Bcl-x(L) promotes Bax translocation during TNFalpha-induced apoptosis.
    Zhang L, Xing D, Chen M.
    Apoptosis; 2008 Jul 17; 13(7):950-8. PubMed ID: 18500555
    [Abstract] [Full Text] [Related]

  • 18. The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis.
    Chu F, Borthakur A, Sun X, Barkinge J, Gudi R, Hawkins S, Prasad KV.
    Apoptosis; 2004 Jan 17; 9(1):83-95. PubMed ID: 14739602
    [Abstract] [Full Text] [Related]

  • 19. Prometaphase arrest-dependent phosphorylation of Bcl-2 and Bim reduces the association of Bcl-2 with Bak or Bim, provoking Bak activation and mitochondrial apoptosis in nocodazole-treated Jurkat T cells.
    Han CR, Jun do Y, Lee JY, Kim YH.
    Apoptosis; 2014 Jan 17; 19(1):224-40. PubMed ID: 24166139
    [Abstract] [Full Text] [Related]

  • 20. Involvement of Akt in mitochondria-dependent apoptosis induced by a cdc25 phosphatase inhibitor naphthoquinone analog.
    Kim HJ, Kang SK, Mun JY, Chun YJ, Choi KH, Kim MY.
    FEBS Lett; 2003 Dec 04; 555(2):217-22. PubMed ID: 14644418
    [Abstract] [Full Text] [Related]

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