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90 related items for PubMed ID: 14560959

  • 1. Modulation of the protein kinase activity of mTOR.
    Lawrence JC, Lin TA, McMahon LP, Choi KM.
    Curr Top Microbiol Immunol; 2004; 279():199-213. PubMed ID: 14560959
    [Abstract] [Full Text] [Related]

  • 2. Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway.
    Scott PH, Brunn GJ, Kohn AD, Roth RA, Lawrence JC.
    Proc Natl Acad Sci U S A; 1998 Jun 23; 95(13):7772-7. PubMed ID: 9636226
    [Abstract] [Full Text] [Related]

  • 3. The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin.
    McMahon LP, Choi KM, Lin TA, Abraham RT, Lawrence JC.
    Mol Cell Biol; 2002 Nov 23; 22(21):7428-38. PubMed ID: 12370290
    [Abstract] [Full Text] [Related]

  • 4. Attenuation of mammalian target of rapamycin activity by increased cAMP in 3T3-L1 adipocytes.
    Scott PH, Lawrence JC.
    J Biol Chem; 1998 Dec 18; 273(51):34496-501. PubMed ID: 9852118
    [Abstract] [Full Text] [Related]

  • 5. Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor.
    Choi KM, McMahon LP, Lawrence JC.
    J Biol Chem; 2003 May 30; 278(22):19667-73. PubMed ID: 12665511
    [Abstract] [Full Text] [Related]

  • 6. In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.
    Mothe-Satney I, Gautier N, Hinault C, Lawrence JC, Van Obberghen E.
    J Biol Chem; 2004 Oct 08; 279(41):42628-37. PubMed ID: 15292249
    [Abstract] [Full Text] [Related]

  • 7. Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells.
    Bishop JD, Nien WL, Dauphinee SM, Too CK.
    J Endocrinol; 2006 Aug 08; 190(2):307-12. PubMed ID: 16899564
    [Abstract] [Full Text] [Related]

  • 8. Kinase activities associated with mTOR.
    Yonezawa K, Yoshino KI, Tokunaga C, Hara K.
    Curr Top Microbiol Immunol; 2004 Aug 08; 279():271-82. PubMed ID: 14560963
    [Abstract] [Full Text] [Related]

  • 9. Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1.
    Wang L, Rhodes CJ, Lawrence JC.
    J Biol Chem; 2006 Aug 25; 281(34):24293-303. PubMed ID: 16798736
    [Abstract] [Full Text] [Related]

  • 10. Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.
    Tremblay F, Gagnon A, Veilleux A, Sorisky A, Marette A.
    Endocrinology; 2005 Mar 25; 146(3):1328-37. PubMed ID: 15576463
    [Abstract] [Full Text] [Related]

  • 11. Mammalian target of rapamycin-dependent phosphorylation of PHAS-I in four (S/T)P sites detected by phospho-specific antibodies.
    Mothe-Satney I, Brunn GJ, McMahon LP, Capaldo CT, Abraham RT, Lawrence JC.
    J Biol Chem; 2000 Oct 27; 275(43):33836-43. PubMed ID: 10942774
    [Abstract] [Full Text] [Related]

  • 12. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
    Sekulić A, Hudson CC, Homme JL, Yin P, Otterness DM, Karnitz LM, Abraham RT.
    Cancer Res; 2000 Jul 01; 60(13):3504-13. PubMed ID: 10910062
    [Abstract] [Full Text] [Related]

  • 13. Farnesylthiosalicylic acid inhibits mammalian target of rapamycin (mTOR) activity both in cells and in vitro by promoting dissociation of the mTOR-raptor complex.
    McMahon LP, Yue W, Santen RJ, Lawrence JC.
    Mol Endocrinol; 2005 Jan 01; 19(1):175-83. PubMed ID: 15459249
    [Abstract] [Full Text] [Related]

  • 14. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A, Usui I, Haruta T, Kawahara J, Uno T, Iwata M, Kobayashi M.
    Mol Cell Biol; 2001 Aug 01; 21(15):5050-62. PubMed ID: 11438661
    [Abstract] [Full Text] [Related]

  • 15. Amino acids and leucine allow insulin activation of the PKB/mTOR pathway in normal adipocytes treated with wortmannin and in adipocytes from db/db mice.
    Hinault C, Mothe-Satney I, Gautier N, Lawrence JC, Van Obberghen E.
    FASEB J; 2004 Dec 01; 18(15):1894-6. PubMed ID: 15479767
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1.
    El-Chaâr D, Gagnon A, Sorisky A.
    Int J Obes Relat Metab Disord; 2004 Feb 01; 28(2):191-8. PubMed ID: 14970836
    [Abstract] [Full Text] [Related]

  • 17. mTOR-mediated regulation of translation factors by amino acids.
    Proud CG.
    Biochem Biophys Res Commun; 2004 Jan 09; 313(2):429-36. PubMed ID: 14684180
    [Abstract] [Full Text] [Related]

  • 18. Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.
    Wang X, Beugnet A, Murakami M, Yamanaka S, Proud CG.
    Mol Cell Biol; 2005 Apr 09; 25(7):2558-72. PubMed ID: 15767663
    [Abstract] [Full Text] [Related]

  • 19. Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin.
    Brunn GJ, Hudson CC, Sekulić A, Williams JM, Hosoi H, Houghton PJ, Lawrence JC, Abraham RT.
    Science; 1997 Jul 04; 277(5322):99-101. PubMed ID: 9204908
    [Abstract] [Full Text] [Related]

  • 20. TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function.
    Schalm SS, Fingar DC, Sabatini DM, Blenis J.
    Curr Biol; 2003 May 13; 13(10):797-806. PubMed ID: 12747827
    [Abstract] [Full Text] [Related]

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