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85 related items for PubMed ID: 14563493

  • 1. Characterisation of C5a receptor agonists from phage display libraries.
    Cain SA, Higginbottom A, Monk PN.
    Biochem Pharmacol; 2003 Nov 01; 66(9):1833-40. PubMed ID: 14563493
    [Abstract] [Full Text] [Related]

  • 2. The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding.
    Scola AM, Higginbottom A, Partridge LJ, Reid RC, Woodruff T, Taylor SM, Fairlie DP, Monk PN.
    J Biol Chem; 2007 Feb 09; 282(6):3664-71. PubMed ID: 17158873
    [Abstract] [Full Text] [Related]

  • 3. C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2.
    Croker DE, Halai R, Fairlie DP, Cooper MA.
    Immunol Cell Biol; 2013 Feb 09; 91(10):625-33. PubMed ID: 24060963
    [Abstract] [Full Text] [Related]

  • 4. Receptor activation by human C5a des Arg74 but not intact C5a is dependent on an interaction between Glu199 of the receptor and Lys68 of the ligand.
    Crass T, Bautsch W, Cain SA, Pease JE, Monk PN.
    Biochemistry; 1999 Jul 27; 38(30):9712-7. PubMed ID: 10423250
    [Abstract] [Full Text] [Related]

  • 5. A detailed analysis of the C5a anaphylatoxin effector domain: selection of C5a phage libraries on differentiated U937 cells.
    Hennecke M, Otto A, Baensch M, Kola A, Bautsch W, Klos A, Köhl J.
    Eur J Biochem; 1998 Feb 15; 252(1):36-44. PubMed ID: 9523709
    [Abstract] [Full Text] [Related]

  • 6. Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site.
    Higginbottom A, Cain SA, Woodruff TM, Proctor LM, Madala PK, Tyndall JD, Taylor SM, Fairlie DP, Monk PN.
    J Biol Chem; 2005 May 06; 280(18):17831-40. PubMed ID: 15661745
    [Abstract] [Full Text] [Related]

  • 7. Mapping the ligand-binding site on the C5a receptor: arginine74 of C5a contacts aspartate282 of the C5a receptor.
    Cain SA, Coughlan T, Monk PN.
    Biochemistry; 2001 Nov 20; 40(46):14047-52. PubMed ID: 11705397
    [Abstract] [Full Text] [Related]

  • 8. Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptor.
    Cain SA, Woodruff TM, Taylor SM, Fairlie DP, Sanderson SD, Monk PN.
    Biochem Pharmacol; 2001 Jun 15; 61(12):1571-9. PubMed ID: 11377387
    [Abstract] [Full Text] [Related]

  • 9. Mutation of glutamate 199 of the human C5a receptor defines a binding site for ligand distinct from the receptor N terminus.
    Monk PN, Barker MD, Partridge LJ, Pease JE.
    J Biol Chem; 1995 Jul 14; 270(28):16625-9. PubMed ID: 7622471
    [Abstract] [Full Text] [Related]

  • 10. Analysis of the C5a anaphylatoxin core domain using a C5a phage library selected on differentiated U937 cells.
    Kola A, Baensch M, Bautsch W, Klos A, Köhl J.
    Mol Immunol; 1999 Feb 14; 36(2):145-52. PubMed ID: 10378686
    [Abstract] [Full Text] [Related]

  • 11. Site-directed mutagenesis of conserved charged residues in the helical region of the human C5a receptor. Arg2O6 determines high-affinity binding sites of C5a receptor.
    Raffetseder U, Röper D, Mery L, Gietz C, Klos A, Grötzinger J, Wollmer A, Boulay F, Köhl J, Bautsch W.
    Eur J Biochem; 1996 Jan 15; 235(1-2):82-90. PubMed ID: 8631370
    [Abstract] [Full Text] [Related]

  • 12. The C terminus of the human C5a receptor (CD88) is required for normal ligand-dependent receptor internalization.
    Bock D, Martin U, Gärtner S, Rheinheimer C, Raffetseder U, Arseniev L, Barker MD, Monk PN, Bautsch W, Köhl J, Klos A.
    Eur J Immunol; 1997 Jun 15; 27(6):1522-9. PubMed ID: 9209506
    [Abstract] [Full Text] [Related]

  • 13. Cleavage of the human C5A receptor by proteinases derived from Porphyromonas gingivalis: cleavage of leukocyte C5a receptor.
    Jagels MA, Ember JA, Travis J, Potempa J, Pike R, Hugli TE.
    Adv Exp Med Biol; 1996 Jun 15; 389():155-64. PubMed ID: 8861006
    [Abstract] [Full Text] [Related]

  • 14. Direct binding of a fragment of the Wiskott-Aldrich syndrome protein to the C-terminal end of the anaphylatoxin C5a receptor.
    Tardif M, Brouchon L, Rabiet MJ, Boulay F.
    Biochem J; 2003 Jun 01; 372(Pt 2):453-63. PubMed ID: 12600272
    [Abstract] [Full Text] [Related]

  • 15. Requirements for C5a receptor-mediated IL-4 and IL-13 production and leukotriene C4 generation in human basophils.
    Eglite S, Plüss K, Dahinden CA.
    J Immunol; 2000 Aug 15; 165(4):2183-9. PubMed ID: 10925305
    [Abstract] [Full Text] [Related]

  • 16. Agonist-dependent phosphorylation of N-formylpeptide and activation peptide from the fifth component of C (C5a) chemoattractant receptors in differentiated HL60 cells.
    Tardif M, Mery L, Brouchon L, Boulay F.
    J Immunol; 1993 Apr 15; 150(8 Pt 1):3534-45. PubMed ID: 8468487
    [Abstract] [Full Text] [Related]

  • 17. Plasma clearance of the human C5a anaphylatoxin by binding to leucocyte C5a receptors.
    Oppermann M, Götze O.
    Immunology; 1994 Aug 15; 82(4):516-21. PubMed ID: 7835913
    [Abstract] [Full Text] [Related]

  • 18. Identification of classical anaphylatoxin as the des-Arg form of the C5a molecule: evidence of a modulator role for the oligosaccharide unit in human des-Arg74-C5a.
    Gerard C, Hugli TE.
    Proc Natl Acad Sci U S A; 1981 Mar 15; 78(3):1833-7. PubMed ID: 6940191
    [Abstract] [Full Text] [Related]

  • 19. Structural complexes of the agonist, inverse agonist and antagonist bound C5a receptor: insights into pharmacology and signaling.
    Rana S, Sahoo AR, Majhi BK.
    Mol Biosyst; 2016 Apr 26; 12(5):1586-99. PubMed ID: 26978009
    [Abstract] [Full Text] [Related]

  • 20. Random mutagenesis of the complement factor 5a (C5a) receptor N terminus provides a structural constraint for C5a docking.
    Hagemann IS, Narzinski KD, Floyd DH, Baranski TJ.
    J Biol Chem; 2006 Dec 01; 281(48):36783-92. PubMed ID: 17023413
    [Abstract] [Full Text] [Related]

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