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269 related items for PubMed ID: 14567627

  • 1. Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl isothiocyanate (PEITC).
    Keum YS, Owuor ED, Kim BR, Hu R, Kong AN.
    Pharm Res; 2003 Sep; 20(9):1351-6. PubMed ID: 14567627
    [Abstract] [Full Text] [Related]

  • 2. Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1.
    Yu R, Jiao JJ, Duh JL, Tan TH, Kong AN.
    Cancer Res; 1996 Jul 01; 56(13):2954-9. PubMed ID: 8674048
    [Abstract] [Full Text] [Related]

  • 3. Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2.
    Xu C, Yuan X, Pan Z, Shen G, Kim JH, Yu S, Khor TO, Li W, Ma J, Kong AN.
    Mol Cancer Ther; 2006 Aug 01; 5(8):1918-26. PubMed ID: 16928811
    [Abstract] [Full Text] [Related]

  • 4. Identification of Nrf2-regulated genes induced by chemopreventive isothiocyanate PEITC by oligonucleotide microarray.
    Hu R, Xu C, Shen G, Jain MR, Khor TO, Gopalkrishnan A, Lin W, Reddy B, Chan JY, Kong AN.
    Life Sci; 2006 Oct 12; 79(20):1944-55. PubMed ID: 16828809
    [Abstract] [Full Text] [Related]

  • 5. Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE).
    Kong AN, Owuor E, Yu R, Hebbar V, Chen C, Hu R, Mandlekar S.
    Drug Metab Rev; 2001 Oct 12; 33(3-4):255-71. PubMed ID: 11768769
    [Abstract] [Full Text] [Related]

  • 6. Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates.
    Chen YR, Wang W, Kong AN, Tan TH.
    J Biol Chem; 1998 Jan 16; 273(3):1769-75. PubMed ID: 9430725
    [Abstract] [Full Text] [Related]

  • 7. ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells.
    Xu C, Shen G, Yuan X, Kim JH, Gopalkrishnan A, Keum YS, Nair S, Kong AN.
    Carcinogenesis; 2006 Mar 16; 27(3):437-45. PubMed ID: 16272172
    [Abstract] [Full Text] [Related]

  • 8. Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates.
    Saw CL, Cintrón M, Wu TY, Guo Y, Huang Y, Jeong WS, Kong AN.
    Biopharm Drug Dispos; 2011 Jul 16; 32(5):289-300. PubMed ID: 21656528
    [Abstract] [Full Text] [Related]

  • 9. Structural influence of isothiocyanates on the antioxidant response element (ARE)-mediated heme oxygenase-1 (HO-1) expression.
    Prawan A, Keum YS, Khor TO, Yu S, Nair S, Li W, Hu L, Kong AN.
    Pharm Res; 2008 Apr 16; 25(4):836-44. PubMed ID: 17657593
    [Abstract] [Full Text] [Related]

  • 10. The chemopreventive agent phenethyl isothiocyanate sensitizes cells to Fas-mediated apoptosis.
    Pullar JM, Thomson SJ, King MJ, Turnbull CI, Midwinter RG, Hampton MB.
    Carcinogenesis; 2004 May 16; 25(5):765-72. PubMed ID: 14729592
    [Abstract] [Full Text] [Related]

  • 11. Phenethyl isothiocyanate-induced apoptosis in p53-deficient PC-3 human prostate cancer cell line is mediated by extracellular signal-regulated kinases.
    Xiao D, Singh SV.
    Cancer Res; 2002 Jul 01; 62(13):3615-9. PubMed ID: 12097262
    [Abstract] [Full Text] [Related]

  • 12. Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals.
    Chen C, Pung D, Leong V, Hebbar V, Shen G, Nair S, Li W, Kong AN.
    Free Radic Biol Med; 2004 Nov 15; 37(10):1578-90. PubMed ID: 15477009
    [Abstract] [Full Text] [Related]

  • 13. Phenethyl isothiocyanate (PEITC) inhibits growth of ovarian cancer cells by inducing apoptosis: role of caspase and MAPK activation.
    Satyan KS, Swamy N, Dizon DS, Singh R, Granai CO, Brard L.
    Gynecol Oncol; 2006 Oct 15; 103(1):261-70. PubMed ID: 16624391
    [Abstract] [Full Text] [Related]

  • 14. The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells.
    Hu R, Kim BR, Chen C, Hebbar V, Kong AN.
    Carcinogenesis; 2003 Aug 15; 24(8):1361-7. PubMed ID: 12819185
    [Abstract] [Full Text] [Related]

  • 15. Nrf2 as a novel molecular target for chemoprevention.
    Lee JS, Surh YJ.
    Cancer Lett; 2005 Jun 28; 224(2):171-84. PubMed ID: 15914268
    [Abstract] [Full Text] [Related]

  • 16. Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter.
    Kwak MK, Itoh K, Yamamoto M, Kensler TW.
    Mol Cell Biol; 2002 May 28; 22(9):2883-92. PubMed ID: 11940647
    [Abstract] [Full Text] [Related]

  • 17. Signal transduction events elicited by cancer prevention compounds.
    Kong AN, Yu R, Hebbar V, Chen C, Owuor E, Hu R, Ee R, Mandlekar S.
    Mutat Res; 2001 Sep 01; 480-481():231-41. PubMed ID: 11506817
    [Abstract] [Full Text] [Related]

  • 18. Antioxidants and oxidants regulated signal transduction pathways.
    Owuor ED, Kong AN.
    Biochem Pharmacol; 2002 Sep 01; 64(5-6):765-70. PubMed ID: 12213568
    [Abstract] [Full Text] [Related]

  • 19. c-jun/AP-1 activation does not affect the antiproliferative activity of phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent.
    Yao S, Zhang Y, Li J.
    Mol Carcinog; 2006 Aug 01; 45(8):605-12. PubMed ID: 16652374
    [Abstract] [Full Text] [Related]

  • 20. Differential hepatic GSTA2 expression of arylalkyl isothiocyanates in vivo and in vitro: the molecular mechanism of gene induction by phenethyl isothiocyanate.
    Gum SI, Cho MK.
    Mol Nutr Food Res; 2013 Dec 01; 57(12):2223-32. PubMed ID: 24039128
    [Abstract] [Full Text] [Related]


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