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Journal Abstract Search

151 related items for PubMed ID: 14570769

  • 1. Mechanism-based inactivation of human recombinant P450 2C9 by the nonsteroidal anti-inflammatory drug suprofen.
    O'Donnell JP, Dalvie DK, Kalgutkar AS, Obach RS.
    Drug Metab Dispos; 2003 Nov; 31(11):1369-77. PubMed ID: 14570769
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  • 3. Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac.
    Tang W, Stearns RA, Wang RW, Chiu SH, Baillie TA.
    Chem Res Toxicol; 1999 Feb; 12(2):192-9. PubMed ID: 10027798
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  • 5. Metabolic activation of diclofenac by human cytochrome P450 3A4: role of 5-hydroxydiclofenac.
    Shen S, Marchick MR, Davis MR, Doss GA, Pohl LR.
    Chem Res Toxicol; 1999 Feb; 12(2):214-22. PubMed ID: 10027801
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  • 6. Thiophene derivatives as new mechanism-based inhibitors of cytochromes P-450: inactivation of yeast-expressed human liver cytochrome P-450 2C9 by tienilic acid.
    López-Garcia MP, Dansette PM, Mansuy D.
    Biochemistry; 1994 Jan 11; 33(1):166-75. PubMed ID: 8286335
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  • 7. Mechanism-based inactivation of cytochrome P450 3A4 by 4-ipomeanol.
    Alvarez-Diez TM, Zheng J.
    Chem Res Toxicol; 2004 Feb 11; 17(2):150-7. PubMed ID: 14967002
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  • 8. Mechanism-based inactivation of cytochrome P450 2B4 by aldehydes: relationship to aldehyde deformylation via a peroxyhemiacetal intermediate.
    Raner GM, Chiang EW, Vaz AD, Coon MJ.
    Biochemistry; 1997 Apr 22; 36(16):4895-902. PubMed ID: 9125510
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  • 9. A novel bioactivation pathway for 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid (diclofenac) initiated by cytochrome P450-mediated oxidative decarboxylation.
    Grillo MP, Ma J, Teffera Y, Waldon DJ.
    Drug Metab Dispos; 2008 Sep 22; 36(9):1740-4. PubMed ID: 18541695
    [Abstract] [Full Text] [Related]

  • 10. Electrospray ionization mass spectrometric analysis of intact cytochrome P450: identification of tienilic acid adducts to P450 2C9.
    Koenigs LL, Peter RM, Hunter AP, Haining RL, Rettie AE, Friedberg T, Pritchard MP, Shou M, Rushmore TH, Trager WF.
    Biochemistry; 1999 Feb 23; 38(8):2312-9. PubMed ID: 10029524
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  • 11. Mechanism-based inactivation of rat liver cytochrome P4502B1 by phencyclidine and its oxidative product, the iminium ion.
    Crowley JR, Hollenberg PF.
    Drug Metab Dispos; 1995 Aug 23; 23(8):786-93. PubMed ID: 7493543
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  • 12. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.
    Zhao SX, Dalvie DK, Kelly JM, Soglia JR, Frederick KS, Smith EB, Obach RS, Kalgutkar AS.
    Chem Res Toxicol; 2007 Nov 23; 20(11):1649-57. PubMed ID: 17907785
    [Abstract] [Full Text] [Related]

  • 13. Inactivation of cytochrome P450 2E1 by tert-butylisothiocyanate.
    Kent UM, Roberts ES, Chun J, Hodge K, Juncaj J, Hollenberg PF.
    Chem Res Toxicol; 1998 Oct 23; 11(10):1154-61. PubMed ID: 9778311
    [Abstract] [Full Text] [Related]

  • 14. Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases.
    Sridar C, Goosen TC, Kent UM, Williams JA, Hollenberg PF.
    Drug Metab Dispos; 2004 Jun 23; 32(6):587-94. PubMed ID: 15155549
    [Abstract] [Full Text] [Related]

  • 15. Mechanism-based inactivation of cytochrome P450 2B1 by N-benzyl-1-aminobenzotriazole.
    Kent UM, Bend JR, Chamberlin BA, Gage DA, Hollenberg PF.
    Chem Res Toxicol; 1997 May 23; 10(5):600-8. PubMed ID: 9168259
    [Abstract] [Full Text] [Related]

  • 16. Effects of 8-methoxypsoralen on cytochrome P450 2A13.
    von Weymarn LB, Zhang QY, Ding X, Hollenberg PF.
    Carcinogenesis; 2005 Mar 23; 26(3):621-9. PubMed ID: 15579482
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  • 17. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by n-propylxanthate.
    Kent UM, Yanev S, Hollenberg PF.
    Chem Res Toxicol; 1999 Apr 23; 12(4):317-22. PubMed ID: 10207119
    [Abstract] [Full Text] [Related]

  • 18. Opposite behaviors of reactive metabolites of tienilic acid and its isomer toward liver proteins: use of specific anti-tienilic acid-protein adduct antibodies and the possible relationship with different hepatotoxic effects of the two compounds.
    Bonierbale E, Valadon P, Pons C, Desfosses B, Dansette PM, Mansuy D.
    Chem Res Toxicol; 1999 Mar 23; 12(3):286-96. PubMed ID: 10077492
    [Abstract] [Full Text] [Related]

  • 19. Novel metabolic bioactivation mechanism for a series of anti-inflammatory agents (2,5-diaminothiophene derivatives) mediated by cytochrome p450 enzymes.
    Hu Y, Yang S, Shilliday FB, Heyde BR, Mandrell KM, Robins RH, Xie J, Reding MT, Lai Y, Thompson DC.
    Drug Metab Dispos; 2010 Sep 23; 38(9):1522-31. PubMed ID: 20530221
    [Abstract] [Full Text] [Related]

  • 20. Phenytoin metabolism by human cytochrome P450: involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation.
    Cuttle L, Munns AJ, Hogg NA, Scott JR, Hooper WD, Dickinson RG, Gillam EM.
    Drug Metab Dispos; 2000 Aug 23; 28(8):945-50. PubMed ID: 10901705
    [Abstract] [Full Text] [Related]

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