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144 related items for PubMed ID: 14573750

  • 1. Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase A3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element.
    Jowsey IR, Jiang Q, Itoh K, Yamamoto M, Hayes JD.
    Mol Pharmacol; 2003 Nov; 64(5):1018-28. PubMed ID: 14573750
    [Abstract] [Full Text] [Related]

  • 2. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.
    Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, Biswal S.
    Cancer Res; 2002 Sep 15; 62(18):5196-203. PubMed ID: 12234984
    [Abstract] [Full Text] [Related]

  • 3. Glutathione-S-transferase A3 knockout mice are sensitive to acute cytotoxic and genotoxic effects of aflatoxin B1.
    Ilic Z, Crawford D, Vakharia D, Egner PA, Sell S.
    Toxicol Appl Pharmacol; 2010 Feb 01; 242(3):241-6. PubMed ID: 19850059
    [Abstract] [Full Text] [Related]

  • 4. Expression of stably transfected murine glutathione S-transferase A3-3 protects against nucleic acid alkylation and cytotoxicity by aflatoxin B1 in hamster V79 cells expressing rat cytochrome P450-2B1.
    Fields WR, Morrow CS, Doehmer J, Townsend AJ.
    Carcinogenesis; 1999 Jun 01; 20(6):1121-5. PubMed ID: 10357798
    [Abstract] [Full Text] [Related]

  • 5. Activation of mouse Pi-class glutathione S-transferase gene by Nrf2(NF-E2-related factor 2) and androgen.
    Ikeda H, Serria MS, Kakizaki I, Hatayama I, Satoh K, Tsuchida S, Muramatsu M, Nishi S, Sakai M.
    Biochem J; 2002 Jun 01; 364(Pt 2):563-70. PubMed ID: 12023900
    [Abstract] [Full Text] [Related]

  • 6. The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.
    McMahon M, Itoh K, Yamamoto M, Chanas SA, Henderson CJ, McLellan LI, Wolf CR, Cavin C, Hayes JD.
    Cancer Res; 2001 Apr 15; 61(8):3299-307. PubMed ID: 11309284
    [Abstract] [Full Text] [Related]

  • 7. Identification of amino acid residues essential for high aflatoxin B1-8,9-epoxide conjugation activity in alpha class glutathione S-transferases through site-directed mutagenesis.
    Van Ness KP, McHugh TE, Bammler TK, Eaton DL.
    Toxicol Appl Pharmacol; 1998 Sep 15; 152(1):166-74. PubMed ID: 9772212
    [Abstract] [Full Text] [Related]

  • 8. Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence.
    Nioi P, McMahon M, Itoh K, Yamamoto M, Hayes JD.
    Biochem J; 2003 Sep 01; 374(Pt 2):337-48. PubMed ID: 12816537
    [Abstract] [Full Text] [Related]

  • 9. Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.
    Chanas SA, Jiang Q, McMahon M, McWalter GK, McLellan LI, Elcombe CR, Henderson CJ, Wolf CR, Moffat GJ, Itoh K, Yamamoto M, Hayes JD.
    Biochem J; 2002 Jul 15; 365(Pt 2):405-16. PubMed ID: 11991805
    [Abstract] [Full Text] [Related]

  • 10. Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.
    Kwak MK, Itoh K, Yamamoto M, Sutter TR, Kensler TW.
    Mol Med; 2001 Feb 15; 7(2):135-45. PubMed ID: 11471548
    [Abstract] [Full Text] [Related]

  • 11. Molecular cloning and heterologous expression of a cDNA encoding a mouse glutathione S-transferase Yc subunit possessing high catalytic activity for aflatoxin B1-8,9-epoxide.
    Hayes JD, Judah DJ, Neal GE, Nguyen T.
    Biochem J; 1992 Jul 01; 285 ( Pt 1)(Pt 1):173-80. PubMed ID: 1637297
    [Abstract] [Full Text] [Related]

  • 12. Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: mechanisms of inducible resistance to aflatoxin B1.
    Hayes JD, Pulford DJ, Ellis EM, McLeod R, James RF, Seidegård J, Mosialou E, Jernström B, Neal GE.
    Chem Biol Interact; 1998 Apr 24; 111-112():51-67. PubMed ID: 9679543
    [Abstract] [Full Text] [Related]

  • 13. Characterization of the rat glutathione S-transferase Yc2 subunit gene, GSTA5: identification of a putative antioxidant-responsive element in the 5'-flanking region of rat GSTA5 that may mediate chemoprotection against aflatoxin B1.
    Pulford DJ, Hayes JD.
    Biochem J; 1996 Aug 15; 318 ( Pt 1)(Pt 1):75-84. PubMed ID: 8761455
    [Abstract] [Full Text] [Related]

  • 14. Transcription factor Nrf2/MafK regulates rat placental glutathione S-transferase gene during hepatocarcinogenesis.
    Ikeda H, Nishi S, Sakai M.
    Biochem J; 2004 Jun 01; 380(Pt 2):515-21. PubMed ID: 14960151
    [Abstract] [Full Text] [Related]

  • 15. Binding of the aflatoxin-glutathione conjugate to mouse glutathione S-transferase A3-3 is saturated at only one ligand per dimer.
    McHugh TE, Atkins WM, Racha JK, Kunze KL, Eaton DL.
    J Biol Chem; 1996 Nov 01; 271(44):27470-4. PubMed ID: 8910329
    [Abstract] [Full Text] [Related]

  • 16. Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.
    Katsuoka F, Motohashi H, Engel JD, Yamamoto M.
    J Biol Chem; 2005 Feb 11; 280(6):4483-90. PubMed ID: 15574414
    [Abstract] [Full Text] [Related]

  • 17. A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway.
    Morimitsu Y, Nakagawa Y, Hayashi K, Fujii H, Kumagai T, Nakamura Y, Osawa T, Horio F, Itoh K, Iida K, Yamamoto M, Uchida K.
    J Biol Chem; 2002 Feb 01; 277(5):3456-63. PubMed ID: 11706044
    [Abstract] [Full Text] [Related]

  • 18. Sulforaphane and alpha-lipoic acid upregulate the expression of the pi class of glutathione S-transferase through c-jun and Nrf2 activation.
    Lii CK, Liu KL, Cheng YP, Lin AH, Chen HW, Tsai CW.
    J Nutr; 2010 May 01; 140(5):885-92. PubMed ID: 20237067
    [Abstract] [Full Text] [Related]

  • 19. Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2.
    Singh A, Rangasamy T, Thimmulappa RK, Lee H, Osburn WO, Brigelius-Flohé R, Kensler TW, Yamamoto M, Biswal S.
    Am J Respir Cell Mol Biol; 2006 Dec 01; 35(6):639-50. PubMed ID: 16794261
    [Abstract] [Full Text] [Related]

  • 20. Ethoxyquin-induced resistance to aflatoxin B1 in the rat is associated with the expression of a novel alpha-class glutathione S-transferase subunit, Yc2, which possesses high catalytic activity for aflatoxin B1-8,9-epoxide.
    Hayes JD, Judah DJ, McLellan LI, Kerr LA, Peacock SD, Neal GE.
    Biochem J; 1991 Oct 15; 279 ( Pt 2)(Pt 2):385-98. PubMed ID: 1953636
    [Abstract] [Full Text] [Related]

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