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158 related items for PubMed ID: 14576831

  • 1. Type-2A protein phosphatase activity is required to maintain death receptor responsiveness.
    Härmälä-Braskén AS, Mikhailov A, Söderström TS, Meinander A, Holmström TH, Damuni Z, Eriksson JE.
    Oncogene; 2003 Oct 23; 22(48):7677-86. PubMed ID: 14576831
    [Abstract] [Full Text] [Related]

  • 2. p38 MAPK regulates phosphorylation of Bad via PP2A-dependent suppression of the MEK1/2-ERK1/2 survival pathway in TNF-alpha induced endothelial apoptosis.
    Grethe S, Pörn-Ares MI.
    Cell Signal; 2006 Apr 23; 18(4):531-40. PubMed ID: 15972258
    [Abstract] [Full Text] [Related]

  • 3. Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-associated p38 mitogen-activated protein kinase.
    Boudreau RT, Conrad DM, Hoskin DW.
    Cell Signal; 2007 Jan 23; 19(1):139-51. PubMed ID: 16844342
    [Abstract] [Full Text] [Related]

  • 4. Protein phosphatase 2A is a critical regulator of protein kinase C zeta signaling targeted by SV40 small t to promote cell growth and NF-kappaB activation.
    Sontag E, Sontag JM, Garcia A.
    EMBO J; 1997 Sep 15; 16(18):5662-71. PubMed ID: 9312025
    [Abstract] [Full Text] [Related]

  • 5. Effect of tumor necrosis factor-alpha on insulin-stimulated mitogen-activated protein kinase cascade in cultured rat skeletal muscle cells.
    Begum N, Ragolia L, Srinivasan M.
    Eur J Biochem; 1996 May 15; 238(1):214-20. PubMed ID: 8665940
    [Abstract] [Full Text] [Related]

  • 6. Inhibitors of protein phosphatases 1 and 2A differentially prevent intrinsic and extrinsic apoptosis pathways.
    Chatfield K, Eastman A.
    Biochem Biophys Res Commun; 2004 Oct 29; 323(4):1313-20. PubMed ID: 15451440
    [Abstract] [Full Text] [Related]

  • 7. MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors.
    Tran SE, Holmstrom TH, Ahonen M, Kahari VM, Eriksson JE.
    J Biol Chem; 2001 May 11; 276(19):16484-90. PubMed ID: 11278665
    [Abstract] [Full Text] [Related]

  • 8. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.
    Yu C, Krystal G, Varticovksi L, McKinstry R, Rahmani M, Dent P, Grant S.
    Cancer Res; 2002 Jan 01; 62(1):188-99. PubMed ID: 11782377
    [Abstract] [Full Text] [Related]

  • 9. p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression.
    Westermarck J, Li SP, Kallunki T, Han J, Kähäri VM.
    Mol Cell Biol; 2001 Apr 01; 21(7):2373-83. PubMed ID: 11259586
    [Abstract] [Full Text] [Related]

  • 10. Positive regulation of Raf1-MEK1/2-ERK1/2 signaling by protein serine/threonine phosphatase 2A holoenzymes.
    Adams DG, Coffee RL, Zhang H, Pelech S, Strack S, Wadzinski BE.
    J Biol Chem; 2005 Dec 30; 280(52):42644-54. PubMed ID: 16239230
    [Abstract] [Full Text] [Related]

  • 11. Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway.
    Chen L, Liu L, Yin J, Luo Y, Huang S.
    Int J Biochem Cell Biol; 2009 Jun 30; 41(6):1284-95. PubMed ID: 19038359
    [Abstract] [Full Text] [Related]

  • 12. Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells.
    Izeradjene K, Douglas L, Delaney A, Houghton JA.
    Clin Cancer Res; 2004 Oct 01; 10(19):6650-60. PubMed ID: 15475455
    [Abstract] [Full Text] [Related]

  • 13. MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly.
    Holmström TH, Schmitz I, Söderström TS, Poukkula M, Johnson VL, Chow SC, Krammer PH, Eriksson JE.
    EMBO J; 2000 Oct 16; 19(20):5418-28. PubMed ID: 11032809
    [Abstract] [Full Text] [Related]

  • 14. Caspase inhibitors induce a switch from apoptotic to proinflammatory signaling in CD95-stimulated T lymphocytes.
    Scheller C, Sopper S, Ehrhardt C, Flory E, Chen P, Koutsilieri E, Ludwig S, ter Meulen V, Jassoy C.
    Eur J Immunol; 2002 Sep 16; 32(9):2471-80. PubMed ID: 12207331
    [Abstract] [Full Text] [Related]

  • 15. Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal.
    Liu W, Akhand AA, Takeda K, Kawamoto Y, Itoigawa M, Kato M, Suzuki H, Ishikawa N, Nakashima I.
    Cell Death Differ; 2003 Jul 16; 10(7):772-81. PubMed ID: 12815460
    [Abstract] [Full Text] [Related]

  • 16. Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.
    Prickett TD, Brautigan DL.
    Mol Cell Biol; 2007 Jun 16; 27(12):4217-27. PubMed ID: 17438131
    [Abstract] [Full Text] [Related]

  • 17. Caspase-8 activation is necessary but not sufficient for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in the prostatic carcinoma cell line LNCaP.
    Rokhlin OW, Guseva NV, Tagiyev AF, Glover RA, Cohen MB.
    Prostate; 2002 Jun 01; 52(1):1-11. PubMed ID: 11992615
    [Abstract] [Full Text] [Related]

  • 18. JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation.
    MacFarlane M, Cohen GM, Dickens M.
    Biochem J; 2000 May 15; 348 Pt 1(Pt 1):93-101. PubMed ID: 10794718
    [Abstract] [Full Text] [Related]

  • 19. Mechanism of chronic obstructive uropathy: increased expression of apoptosis-promoting molecules.
    Choi YJ, Baranowska-Daca E, Nguyen V, Koji T, Ballantyne CM, Sheikh-Hamad D, Suki WN, Truong LD.
    Kidney Int; 2000 Oct 15; 58(4):1481-91. PubMed ID: 11012883
    [Abstract] [Full Text] [Related]

  • 20. A new role of protein phosphatase 2a in adenoviral E1A protein-mediated sensitization to anticancer drug-induced apoptosis in human breast cancer cells.
    Liao Y, Hung MC.
    Cancer Res; 2004 Sep 01; 64(17):5938-42. PubMed ID: 15342371
    [Abstract] [Full Text] [Related]


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