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256 related items for PubMed ID: 14583450

  • 1. The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53.
    Zhou B, Liu X, Mo X, Xue L, Darwish D, Qiu W, Shih J, Hwu EB, Luh F, Yen Y.
    Cancer Res; 2003 Oct 15; 63(20):6583-94. PubMed ID: 14583450
    [Abstract] [Full Text] [Related]

  • 2. Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits.
    Xue L, Zhou B, Liu X, Qiu W, Jin Z, Yen Y.
    Cancer Res; 2003 Mar 01; 63(5):980-6. PubMed ID: 12615712
    [Abstract] [Full Text] [Related]

  • 3. Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits.
    Qiu W, Zhou B, Darwish D, Shao J, Yen Y.
    Biochem Biophys Res Commun; 2006 Feb 10; 340(2):428-34. PubMed ID: 16376858
    [Abstract] [Full Text] [Related]

  • 4. Ribonucleotide reductase subunits M2 and p53R2 are potential biomarkers for metastasis of colon cancer.
    Liu X, Zhou B, Xue L, Yen F, Chu P, Un F, Yen Y.
    Clin Colorectal Cancer; 2007 Jan 10; 6(5):374-81. PubMed ID: 17311703
    [Abstract] [Full Text] [Related]

  • 5. In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase.
    Shao J, Zhou B, Zhu L, Qiu W, Yuan YC, Xi B, Yen Y.
    Cancer Res; 2004 Jan 01; 64(1):1-6. PubMed ID: 14729598
    [Abstract] [Full Text] [Related]

  • 6. Determination of the potency and subunit-selectivity of ribonucleotide reductase inhibitors with a recombinant-holoenzyme-based in vitro assay.
    Shao J, Zhou B, Zhu L, Bilio AJ, Su L, Yuan YC, Ren S, Lien EJ, Shih J, Yen Y.
    Biochem Pharmacol; 2005 Feb 15; 69(4):627-34. PubMed ID: 15670581
    [Abstract] [Full Text] [Related]

  • 7. Metastasis-suppressing potential of ribonucleotide reductase small subunit p53R2 in human cancer cells.
    Liu X, Zhou B, Xue L, Shih J, Tye K, Lin W, Qi C, Chu P, Un F, Wen W, Yen Y.
    Clin Cancer Res; 2006 Nov 01; 12(21):6337-44. PubMed ID: 17085643
    [Abstract] [Full Text] [Related]

  • 8. Expression status of ribonucleotide reductase small subunits hRRM2/p53R2 as prognostic biomarkers in stage I and II non-small cell lung cancer.
    Hsu NY, Wu JY, Liu X, Yen Y, Chen CY, Chou MC, Lin CH, Lee H, Cheng YW.
    Anticancer Res; 2011 Oct 01; 31(10):3475-81. PubMed ID: 21965764
    [Abstract] [Full Text] [Related]

  • 9. Expression and mutation analyses of P53R2, a newly identified p53 target for DNA repair in human gastric carcinoma.
    Byun DS, Chae KS, Ryu BK, Lee MG, Chi SG.
    Int J Cancer; 2002 Apr 10; 98(5):718-23. PubMed ID: 11920641
    [Abstract] [Full Text] [Related]

  • 10. Overexpression of the R2 subunit of ribonucleotide reductase in human nasopharyngeal cancer cells reduces radiosensitivity.
    Kuo ML, Hwang HS, Sosnay PR, Kunugi KA, Kinsella TJ.
    Cancer J; 2003 Apr 10; 9(4):277-85. PubMed ID: 12967138
    [Abstract] [Full Text] [Related]

  • 11. p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint.
    Yamaguchi T, Matsuda K, Sagiya Y, Iwadate M, Fujino MA, Nakamura Y, Arakawa H.
    Cancer Res; 2001 Nov 15; 61(22):8256-62. PubMed ID: 11719458
    [Abstract] [Full Text] [Related]

  • 12. Redox property of ribonucleotide reductase small subunit M2 and p53R2.
    Liu X, Xue L, Yen Y.
    Methods Mol Biol; 2008 Nov 15; 477():195-206. PubMed ID: 19082948
    [Abstract] [Full Text] [Related]

  • 13. Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors.
    Lin ZP, Belcourt MF, Cory JG, Sartorelli AC.
    J Biol Chem; 2004 Jun 25; 279(26):27030-8. PubMed ID: 15096505
    [Abstract] [Full Text] [Related]

  • 14. ATR-CHK1-E2F3 signaling transactivates human ribonucleotide reductase small subunit M2 for DNA repair induced by the chemical carcinogen MNNG.
    Gong C, Liu H, Song R, Zhong T, Lou M, Wang T, Qi H, Shen J, Zhu L, Shao J.
    Biochim Biophys Acta; 2016 Apr 25; 1859(4):612-26. PubMed ID: 26921499
    [Abstract] [Full Text] [Related]

  • 15. Ribonucleotide reductase small subunit p53R2 facilitates p21 induction of G1 arrest under UV irradiation.
    Xue L, Zhou B, Liu X, Heung Y, Chau J, Chu E, Li S, Jiang C, Un F, Yen Y.
    Cancer Res; 2007 Jan 01; 67(1):16-21. PubMed ID: 17210678
    [Abstract] [Full Text] [Related]

  • 16. A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage.
    Tanaka H, Arakawa H, Yamaguchi T, Shiraishi K, Fukuda S, Matsui K, Takei Y, Nakamura Y.
    Nature; 2000 Mar 02; 404(6773):42-9. PubMed ID: 10716435
    [Abstract] [Full Text] [Related]

  • 17. Upregulation of the p53R2 ribonucleotide reductase subunit by nitric oxide.
    Guittet O, Tebbi A, Cottet MH, Vésin F, Lepoivre M.
    Nitric Oxide; 2008 Sep 02; 19(2):84-94. PubMed ID: 18474260
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of human cancer cell growth by inducible expression of human ribonucleotide reductase antisense cDNA.
    Chen S, Zhou B, He F, Yen Y.
    Antisense Nucleic Acid Drug Dev; 2000 Apr 02; 10(2):111-6. PubMed ID: 10805162
    [Abstract] [Full Text] [Related]

  • 19. p53R2 regulates thioredoxin reductase activity through interaction with TrxR2.
    Park SJ, Kim HB, Piao C, Kang MY, Park SG, Kim SW, Lee JH.
    Biochem Biophys Res Commun; 2017 Jan 22; 482(4):706-712. PubMed ID: 27866984
    [Abstract] [Full Text] [Related]

  • 20. p53R2 inhibits the proliferation of human cancer cells in association with cell-cycle arrest.
    Zhang K, Wu J, Wu X, Wang X, Wang Y, Zhou N, Kuo ML, Liu X, Zhou B, Chang L, Ann D, Yen Y.
    Mol Cancer Ther; 2011 Feb 22; 10(2):269-78. PubMed ID: 21216934
    [Abstract] [Full Text] [Related]

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