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Journal Abstract Search

151 related items for PubMed ID: 14592521

  • 1. A new class of glycogen phosphorylase inhibitors.
    Lu Z, Bohn J, Bergeron R, Deng Q, Ellsworth KP, Geissler WM, Harris G, McCann PE, McKeever B, Myers RW, Saperstein R, Willoughby CA, Yao J, Chapman K.
    Bioorg Med Chem Lett; 2003 Nov 17; 13(22):4125-8. PubMed ID: 14592521
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  • 2. Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.
    Chen L, Li H, Liu J, Zhang L, Liu H, Jiang H.
    Bioorg Med Chem; 2007 Nov 01; 15(21):6763-74. PubMed ID: 17719791
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  • 3. Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site.
    Kristiansen M, Andersen B, Iversen LF, Westergaard N.
    J Med Chem; 2004 Jul 01; 47(14):3537-45. PubMed ID: 15214781
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  • 4. Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol.
    Tsitsanou KE, Hayes JM, Keramioti M, Mamais M, Oikonomakos NG, Kato A, Leonidas DD, Zographos SE.
    Food Chem Toxicol; 2013 Nov 01; 61():14-27. PubMed ID: 23279842
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  • 5. New inhibitors of glycogen phosphorylase as potential antidiabetic agents.
    Somsák L, Czifrák K, Tóth M, Bokor E, Chrysina ED, Alexacou KM, Hayes JM, Tiraidis C, Lazoura E, Leonidas DD, Zographos SE, Oikonomakos NG.
    Curr Med Chem; 2008 Nov 01; 15(28):2933-83. PubMed ID: 19075645
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  • 6. Novel 3,4-dihydroquinolin-2(1H)-one inhibitors of human glycogen phosphorylase a.
    Rosauer KG, Ogawa AK, Willoughby CA, Ellsworth KP, Geissler WM, Myers RW, Deng Q, Chapman KT, Harris G, Moller DE.
    Bioorg Med Chem Lett; 2003 Dec 15; 13(24):4385-8. PubMed ID: 14643331
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  • 7. Advances in glycogen phosphorylase inhibitor design.
    Oikonomakos NG, Somsák L.
    Curr Opin Investig Drugs; 2008 Apr 15; 9(4):379-95. PubMed ID: 18393105
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  • 8. Terpenoids. III: Synthesis and biological evaluation of 23-hydroxybetulinic acid derivatives as novel inhibitors of glycogen phosphorylase.
    Zhu P, Bi Y, Xu J, Li Z, Liu J, Zhang L, Ye W, Wu X.
    Bioorg Med Chem Lett; 2009 Dec 15; 19(24):6966-9. PubMed ID: 19889536
    [Abstract] [Full Text] [Related]

  • 9. Modeling aided design of potent glycogen phosphorylase inhibitors.
    Deng Q, Lu Z, Bohn J, Ellsworth KP, Myers RW, Geissler WM, Harris G, Willoughby CA, Chapman K, McKeever B, Mosley R.
    J Mol Graph Model; 2005 Apr 15; 23(5):457-64. PubMed ID: 15781188
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  • 10. Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
    Oikonomakos NG, Tiraidis C, Leonidas DD, Zographos SE, Kristiansen M, Jessen CU, Nørskov-Lauritsen L, Agius L.
    J Med Chem; 2006 Sep 21; 49(19):5687-701. PubMed ID: 16970395
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  • 14. Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
    Wen X, Sun H, Liu J, Cheng K, Zhang P, Zhang L, Hao J, Zhang L, Ni P, Zographos SE, Leonidas DD, Alexacou KM, Gimisis T, Hayes JM, Oikonomakos NG.
    J Med Chem; 2008 Jun 26; 51(12):3540-54. PubMed ID: 18517260
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  • 16. Development of potent, orally active 1-substituted-3,4-dihydro-2-quinolone glycogen phosphorylase inhibitors.
    Birch AM, Kenny PW, Oikonomakos NG, Otterbein L, Schofield P, Whittamore PR, Whalley DP.
    Bioorg Med Chem Lett; 2007 Jan 15; 17(2):394-9. PubMed ID: 17095214
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  • 17. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors.
    Anderka O, Loenze P, Klabunde T, Dreyer MK, Defossa E, Wendt KU, Schmoll D.
    Biochemistry; 2008 Apr 22; 47(16):4683-91. PubMed ID: 18373353
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  • 20. The structure of brain glycogen phosphorylase-from allosteric regulation mechanisms to clinical perspectives.
    Mathieu C, Dupret JM, Rodrigues Lima F.
    FEBS J; 2017 Feb 22; 284(4):546-554. PubMed ID: 27782369
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