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320 related items for PubMed ID: 14596938

  • 1. The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2.
    Paugh SW, Payne SG, Barbour SE, Milstien S, Spiegel S.
    FEBS Lett; 2003 Nov 06; 554(1-2):189-93. PubMed ID: 14596938
    [Abstract] [Full Text] [Related]

  • 2. Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases.
    Billich A, Bornancin F, Dévay P, Mechtcheriakova D, Urtz N, Baumruker T.
    J Biol Chem; 2003 Nov 28; 278(48):47408-15. PubMed ID: 13129923
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  • 3. Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720.
    Zemann B, Kinzel B, Müller M, Reuschel R, Mechtcheriakova D, Urtz N, Bornancin F, Baumruker T, Billich A.
    Blood; 2006 Feb 15; 107(4):1454-8. PubMed ID: 16223773
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  • 4. Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells.
    Nagaoka Y, Otsuki K, Fujita T, Uesato S.
    Biol Pharm Bull; 2008 Jun 15; 31(6):1177-81. PubMed ID: 18520051
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  • 5. Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues.
    Don AS, Martinez-Lamenca C, Webb WR, Proia RL, Roberts E, Rosen H.
    J Biol Chem; 2007 May 25; 282(21):15833-42. PubMed ID: 17400555
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  • 6. FTY720 postconditions isolated perfused heart by a mechanism independent of sphingosine kinase 2 and different from S1P or ischemic postconditioning.
    Vessey DA, Li L, Imhof I, Honbo N, Karliner JS.
    Med Sci Monit Basic Res; 2013 Apr 09; 19():126-32. PubMed ID: 23567658
    [Abstract] [Full Text] [Related]

  • 7. Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.
    Allende ML, Sasaki T, Kawai H, Olivera A, Mi Y, van Echten-Deckert G, Hajdu R, Rosenbach M, Keohane CA, Mandala S, Spiegel S, Proia RL.
    J Biol Chem; 2004 Dec 10; 279(50):52487-92. PubMed ID: 15459201
    [Abstract] [Full Text] [Related]

  • 8. Functional characterization of sphingosine 1-phosphate receptor agonist in human endothelial cells.
    Butler J, Lana D, Round O, LaMontagne K.
    Prostaglandins Other Lipid Mediat; 2004 Jan 10; 73(1-2):29-45. PubMed ID: 15165029
    [Abstract] [Full Text] [Related]

  • 9. Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720.
    Kharel Y, Lee S, Snyder AH, Sheasley-O'neill SL, Morris MA, Setiady Y, Zhu R, Zigler MA, Burcin TL, Ley K, Tung KS, Engelhard VH, Macdonald TL, Pearson-White S, Lynch KR.
    J Biol Chem; 2005 Nov 04; 280(44):36865-72. PubMed ID: 16093248
    [Abstract] [Full Text] [Related]

  • 10. Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.
    Sanchez T, Estrada-Hernandez T, Paik JH, Wu MT, Venkataraman K, Brinkmann V, Claffey K, Hla T.
    J Biol Chem; 2003 Nov 21; 278(47):47281-90. PubMed ID: 12954648
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  • 16. FTY720 (fingolimod) sensitizes prostate cancer cells to radiotherapy by inhibition of sphingosine kinase-1.
    Pchejetski D, Bohler T, Brizuela L, Sauer L, Doumerc N, Golzio M, Salunkhe V, Teissié J, Malavaud B, Waxman J, Cuvillier O.
    Cancer Res; 2010 Nov 01; 70(21):8651-61. PubMed ID: 20959468
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  • 17. Role of the sphingosine metabolism pathway on neurons against experimental cerebral ischemia in rats.
    Hasegawa Y, Suzuki H, Altay O, Rolland W, Zhang JH.
    Transl Stroke Res; 2013 Oct 01; 4(5):524-32. PubMed ID: 24187597
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  • 18. The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720.
    Hisano Y, Kobayashi N, Kawahara A, Yamaguchi A, Nishi T.
    J Biol Chem; 2011 Jan 21; 286(3):1758-66. PubMed ID: 21084291
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  • 20. The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors.
    Payne SG, Oskeritzian CA, Griffiths R, Subramanian P, Barbour SE, Chalfant CE, Milstien S, Spiegel S.
    Blood; 2007 Feb 01; 109(3):1077-85. PubMed ID: 17008548
    [Abstract] [Full Text] [Related]

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