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Journal Abstract Search

169 related items for PubMed ID: 14598312

  • 21. Proprotein convertase activity contributes to the processing of the Alzheimer's beta-amyloid precursor protein in human cells: evidence for a role of the prohormone convertase PC7 in the constitutive alpha-secretase pathway.
    Lopez-Perez E, Seidah NG, Checler F.
    J Neurochem; 1999 Nov; 73(5):2056-62. PubMed ID: 10537065
    [Abstract] [Full Text] [Related]

  • 22. Gamma-secretase activity is present in rafts but is not cholesterol-dependent.
    Wada S, Morishima-Kawashima M, Qi Y, Misono H, Shimada Y, Ohno-Iwashita Y, Ihara Y.
    Biochemistry; 2003 Dec 02; 42(47):13977-86. PubMed ID: 14636066
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  • 23. Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments.
    Vetrivel KS, Thinakaran G.
    Neurology; 2006 Jan 24; 66(2 Suppl 1):S69-73. PubMed ID: 16432149
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  • 24. Presenilin-directed inhibitors of gamma-secretase trigger caspase 3 activation in presenilin-expressing and presenilin-deficient cells.
    Alves da Costa C, Ayral E, Hernandez JF, St George-Hyslop P, Checler F.
    J Neurochem; 2004 Aug 24; 90(4):800-6. PubMed ID: 15287885
    [Abstract] [Full Text] [Related]

  • 25. Cysteine proteases are the major beta-secretase in the regulated secretory pathway that provides most of the beta-amyloid in Alzheimer's disease: role of BACE 1 in the constitutive secretory pathway.
    Hook VY, Reisine TD.
    J Neurosci Res; 2003 Nov 01; 74(3):393-405. PubMed ID: 14598316
    [Abstract] [Full Text] [Related]

  • 26. Presenilins are not required for A beta 42 production in the early secretory pathway.
    Wilson CA, Doms RW, Zheng H, Lee VM.
    Nat Neurosci; 2002 Sep 01; 5(9):849-55. PubMed ID: 12145638
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  • 32. Novel alpha-secretase cleavage of Alzheimer's amyloid beta precursor protein in the endoplasmic reticulum of COS7 cells.
    Shin RW, Saido TC, Maeda M, Kitamoto T.
    Neurosci Lett; 2005 Mar 07; 376(1):14-9. PubMed ID: 15694266
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  • 33. Mutations in APP have independent effects on Abeta and CTFgamma generation.
    Hecimovic S, Wang J, Dolios G, Martinez M, Wang R, Goate AM.
    Neurobiol Dis; 2004 Nov 07; 17(2):205-18. PubMed ID: 15474359
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  • 34. Amyloid precursor protein and Notch intracellular domains are generated after transport of their precursors to the cell surface.
    Kaether C, Schmitt S, Willem M, Haass C.
    Traffic; 2006 Apr 07; 7(4):408-15. PubMed ID: 16536739
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  • 35. The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein.
    Cupers P, Bentahir M, Craessaerts K, Orlans I, Vanderstichele H, Saftig P, De Strooper B, Annaert W.
    J Cell Biol; 2001 Aug 20; 154(4):731-40. PubMed ID: 11502763
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  • 36. Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts.
    Armogida M, Petit A, Vincent B, Scarzello S, da Costa CA, Checler F.
    Nat Cell Biol; 2001 Nov 20; 3(11):1030-3. PubMed ID: 11715026
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  • 37. Alzheimer's disease. Closing in on gamma-secretase.
    De Strooper B.
    Nature; 2000 Jun 08; 405(6787):627, 629. PubMed ID: 10864307
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  • 38. In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc.
    Hoke DE, Tan JL, Ilaya NT, Culvenor JG, Smith SJ, White AR, Masters CL, Evin GM.
    FEBS J; 2005 Nov 08; 272(21):5544-57. PubMed ID: 16262694
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  • 39. Presenilin-dependent gamma-secretase on plasma membrane and endosomes is functionally distinct.
    Fukumori A, Okochi M, Tagami S, Jiang J, Itoh N, Nakayama T, Yanagida K, Ishizuka-Katsura Y, Morihara T, Kamino K, Tanaka T, Kudo T, Tanii H, Ikuta A, Haass C, Takeda M.
    Biochemistry; 2006 Apr 18; 45(15):4907-14. PubMed ID: 16605258
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  • 40. New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage.
    Petit A, Bihel F, Alvès da Costa C, Pourquié O, Checler F, Kraus JL.
    Nat Cell Biol; 2001 May 18; 3(5):507-11. PubMed ID: 11331880
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