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245 related items for PubMed ID: 14603258

  • 1. Herstatin inhibits heregulin-mediated breast cancer cell growth and overcomes tamoxifen resistance in breast cancer cells that overexpress HER-2.
    Jhabvala-Romero F, Evans A, Guo S, Denton M, Clinton GM.
    Oncogene; 2003 Nov 06; 22(50):8178-86. PubMed ID: 14603258
    [Abstract] [Full Text] [Related]

  • 2. The outcome of heregulin-induced activation of ovarian cancer cells depends on the relative levels of HER-2 and HER-3 expression.
    Xu F, Yu Y, Le XF, Boyer C, Mills GB, Bast RC.
    Clin Cancer Res; 1999 Nov 06; 5(11):3653-60. PubMed ID: 10589783
    [Abstract] [Full Text] [Related]

  • 3. Blocking HER-2/HER-3 function with a dominant negative form of HER-3 in cells stimulated by heregulin and in breast cancer cells with HER-2 gene amplification.
    Ram TG, Schelling ME, Hosick HL.
    Cell Growth Differ; 2000 Mar 06; 11(3):173-83. PubMed ID: 10768865
    [Abstract] [Full Text] [Related]

  • 4. The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides.
    Motoyama AB, Hynes NE, Lane HA.
    Cancer Res; 2002 Jun 01; 62(11):3151-8. PubMed ID: 12036928
    [Abstract] [Full Text] [Related]

  • 5. Heregulin-triggered Her-2/neu signaling enhances nuclear accumulation of p21WAF1/CIP1 and protects breast cancer cells from cisplatin-induced genotoxic damage.
    Menendez JA, Mehmi I, Lupu R.
    Int J Oncol; 2005 Mar 01; 26(3):649-59. PubMed ID: 15703820
    [Abstract] [Full Text] [Related]

  • 6. A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4.
    Lee H, Akita RW, Sliwkowski MX, Maihle NJ.
    Cancer Res; 2001 Jun 01; 61(11):4467-73. PubMed ID: 11389077
    [Abstract] [Full Text] [Related]

  • 7. Trastuzumab in combination with heregulin-activated Her-2 (erbB-2) triggers a receptor-enhanced chemosensitivity effect in the absence of Her-2 overexpression.
    Menendez JA, Mehmi I, Lupu R.
    J Clin Oncol; 2006 Aug 10; 24(23):3735-46. PubMed ID: 16847284
    [Abstract] [Full Text] [Related]

  • 8. Epidermal growth factor receptor coexpression modulates susceptibility to Herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation.
    Diermeier S, Horváth G, Knuechel-Clarke R, Hofstaedter F, Szöllosi J, Brockhoff G.
    Exp Cell Res; 2005 Apr 01; 304(2):604-19. PubMed ID: 15748904
    [Abstract] [Full Text] [Related]

  • 9. Heregulin beta1-activated phosphatidylinositol 3-kinase enhances aggregation of MCF-7 breast cancer cells independent of extracellular signal-regulated kinase.
    Tan M, Grijalva R, Yu D.
    Cancer Res; 1999 Apr 01; 59(7):1620-5. PubMed ID: 10197638
    [Abstract] [Full Text] [Related]

  • 10. Gamma-heregulin: a novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175.
    Schaefer G, Fitzpatrick VD, Sliwkowski MX.
    Oncogene; 1997 Sep 18; 15(12):1385-94. PubMed ID: 9333014
    [Abstract] [Full Text] [Related]

  • 11. Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness.
    Lewis GD, Lofgren JA, McMurtrey AE, Nuijens A, Fendly BM, Bauer KD, Sliwkowski MX.
    Cancer Res; 1996 Mar 15; 56(6):1457-65. PubMed ID: 8640840
    [Abstract] [Full Text] [Related]

  • 12. Estrogen receptor-positive, progesterone receptor-negative breast cancer: association with growth factor receptor expression and tamoxifen resistance.
    Arpino G, Weiss H, Lee AV, Schiff R, De Placido S, Osborne CK, Elledge RM.
    J Natl Cancer Inst; 2005 Sep 07; 97(17):1254-61. PubMed ID: 16145046
    [Abstract] [Full Text] [Related]

  • 13. Heregulin-dependent autocrine loop regulates growth of K-ras but not erbB-2 transformed rat thyroid epithelial cells.
    Mincione G, Piccirelli A, Lazzereschi D, Salomon DS, Colletta G.
    J Cell Physiol; 1998 Aug 07; 176(2):383-91. PubMed ID: 9648926
    [Abstract] [Full Text] [Related]

  • 14. Heregulin-beta is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells.
    Ram TG, Hosick HL, Ethier SP.
    J Cell Physiol; 2000 Jun 07; 183(3):301-13. PubMed ID: 10797304
    [Abstract] [Full Text] [Related]

  • 15. Expression of herstatin, an autoinhibitor of HER-2/neu, inhibits transactivation of HER-3 by HER-2 and blocks EGF activation of the EGF receptor.
    Azios NG, Romero FJ, Denton MC, Doherty JK, Clinton GM.
    Oncogene; 2001 Aug 23; 20(37):5199-209. PubMed ID: 11526509
    [Abstract] [Full Text] [Related]

  • 16. HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells.
    Pietras RJ, Arboleda J, Reese DM, Wongvipat N, Pegram MD, Ramos L, Gorman CM, Parker MG, Sliwkowski MX, Slamon DJ.
    Oncogene; 1995 Jun 15; 10(12):2435-46. PubMed ID: 7784095
    [Abstract] [Full Text] [Related]

  • 17. AIB1 is required for the acquisition of epithelial growth factor receptor-mediated tamoxifen resistance in breast cancer cells.
    Zhao W, Zhang Q, Kang X, Jin S, Lou C.
    Biochem Biophys Res Commun; 2009 Mar 13; 380(3):699-704. PubMed ID: 19285025
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of erbB receptor (HER) tyrosine kinases as a strategy to abrogate antiestrogen resistance in human breast cancer.
    Kurokawa H, Arteaga CL.
    Clin Cancer Res; 2001 Dec 13; 7(12 Suppl):4436s-4442s; discussion 4411s-4412s. PubMed ID: 11916237
    [Abstract] [Full Text] [Related]

  • 19. Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo.
    Atlas E, Cardillo M, Mehmi I, Zahedkargaran H, Tang C, Lupu R.
    Mol Cancer Res; 2003 Jan 13; 1(3):165-75. PubMed ID: 12556556
    [Abstract] [Full Text] [Related]

  • 20. Heregulin induces expression, ATPase activity, and nuclear localization of G3BP, a Ras signaling component, in human breast tumors.
    Barnes CJ, Li F, Mandal M, Yang Z, Sahin AA, Kumar R.
    Cancer Res; 2002 Mar 01; 62(5):1251-5. PubMed ID: 11888885
    [Abstract] [Full Text] [Related]

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