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140 related items for PubMed ID: 14610070

  • 1. 12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione.
    Fernández C, Ramos AM, Sancho P, Amrán D, de Blas E, Aller P.
    J Biol Chem; 2004 Jan 30; 279(5):3877-84. PubMed ID: 14610070
    [Abstract] [Full Text] [Related]

  • 2. Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
    Ramos AM, Fernandez C, Amrán D, Esteban D, de Blas E, Palacios MA, Aller P.
    J Cell Physiol; 2006 Dec 30; 209(3):1006-15. PubMed ID: 16972261
    [Abstract] [Full Text] [Related]

  • 3. Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. The role of intracellular oxidation.
    Troyano A, Fernández C, Sancho P, de Blas E, Aller P.
    J Biol Chem; 2001 Dec 14; 276(50):47107-15. PubMed ID: 11602574
    [Abstract] [Full Text] [Related]

  • 4. Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases.
    Sánchez Y, Calle C, de Blas E, Aller P.
    Chem Biol Interact; 2009 Nov 10; 182(1):37-44. PubMed ID: 19720055
    [Abstract] [Full Text] [Related]

  • 5. Apoptosis induced by arsenic trioxide in leukemia U937 cells is dependent on activation of p38, inactivation of ERK and the Ca2+-dependent production of superoxide.
    Iwama K, Nakajo S, Aiuchi T, Nakaya K.
    Int J Cancer; 2001 May 15; 92(4):518-26. PubMed ID: 11304686
    [Abstract] [Full Text] [Related]

  • 6. Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK).
    Sánchez Y, Amrán D, Fernández C, de Blas E, Aller P.
    Int J Cancer; 2008 Sep 01; 123(5):1205-14. PubMed ID: 18546268
    [Abstract] [Full Text] [Related]

  • 7. Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines.
    Ramos AM, Aller P.
    Biochem Pharmacol; 2008 May 15; 75(10):1912-23. PubMed ID: 18359480
    [Abstract] [Full Text] [Related]

  • 8. Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors.
    Chen D, Chan R, Waxman S, Jing Y.
    Cancer Res; 2006 Dec 01; 66(23):11416-23. PubMed ID: 17145888
    [Abstract] [Full Text] [Related]

  • 9. Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways.
    Amrán D, Sánchez Y, Fernández C, Ramos AM, de Blas E, Bréard J, Calle C, Aller P.
    Biochim Biophys Acta; 2007 Nov 01; 1773(11):1653-63. PubMed ID: 17673311
    [Abstract] [Full Text] [Related]

  • 10. Enhancement of esculetin on arsenic trioxide-provoked apoptosis in human leukemia U937 cells.
    Lin TH, Lu FJ, Yin YF, Tseng TH.
    Chem Biol Interact; 2009 Jun 15; 180(1):61-8. PubMed ID: 19428345
    [Abstract] [Full Text] [Related]

  • 11. JNK activation is a mediator of arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells.
    Davison K, Mann KK, Waxman S, Miller WH.
    Blood; 2004 May 01; 103(9):3496-502. PubMed ID: 14701702
    [Abstract] [Full Text] [Related]

  • 12. Arsenic trioxide induces apoptosis in cells of MOLT-4 and its daunorubicin-resistant cell line via depletion of intracellular glutathione, disruption of mitochondrial membrane potential and activation of caspase-3.
    Hu XM, Hirano T, Oka K.
    Cancer Chemother Pharmacol; 2003 Jul 01; 52(1):47-58. PubMed ID: 12750841
    [Abstract] [Full Text] [Related]

  • 13. Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.
    Sánchez Y, Simón GP, Calviño E, de Blas E, Aller P.
    J Pharmacol Exp Ther; 2010 Oct 01; 335(1):114-23. PubMed ID: 20605902
    [Abstract] [Full Text] [Related]

  • 14. Arsenic trioxide induces apoptosis in chronic myelogenous leukemia K562 cells: possible involvement of p38 MAP kinase.
    Shim MJ, Kim HJ, Yang SJ, Lee IS, Choi HI, Kim T.
    J Biochem Mol Biol; 2002 Jul 31; 35(4):377-83. PubMed ID: 12296996
    [Abstract] [Full Text] [Related]

  • 15. Protein kinase C activation modulates pro- and anti-apoptotic signaling pathways.
    Meinhardt G, Roth J, Totok G.
    Eur J Cell Biol; 2000 Nov 31; 79(11):824-33. PubMed ID: 11139146
    [Abstract] [Full Text] [Related]

  • 16. Ultraviolet-induced junD activation and apoptosis in myeloblastic leukemia ML-1 cells.
    Li T, Dai W, Lu L.
    J Biol Chem; 2002 Sep 06; 277(36):32668-76. PubMed ID: 12082101
    [Abstract] [Full Text] [Related]

  • 17. Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis.
    Sordet O, Rébé C, Leroy I, Bruey JM, Garrido C, Miguet C, Lizard G, Plenchette S, Corcos L, Solary E.
    Blood; 2001 Jun 15; 97(12):3931-40. PubMed ID: 11389037
    [Abstract] [Full Text] [Related]

  • 18. Arsenic trioxide induces apoptosis of human monocytes during macrophagic differentiation through nuclear factor-kappaB-related survival pathway down-regulation.
    Lemarie A, Morzadec C, Mérino D, Micheau O, Fardel O, Vernhet L.
    J Pharmacol Exp Ther; 2006 Jan 15; 316(1):304-14. PubMed ID: 16174796
    [Abstract] [Full Text] [Related]

  • 19. Darinaparsin induces a unique cellular response and is active in an arsenic trioxide-resistant myeloma cell line.
    Matulis SM, Morales AA, Yehiayan L, Croutch C, Gutman D, Cai Y, Lee KP, Boise LH.
    Mol Cancer Ther; 2009 May 15; 8(5):1197-206. PubMed ID: 19417148
    [Abstract] [Full Text] [Related]

  • 20. Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells.
    Ramos AM, Fernández C, Amrán D, Sancho P, de Blas E, Aller P.
    Blood; 2005 May 15; 105(10):4013-20. PubMed ID: 15665116
    [Abstract] [Full Text] [Related]


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