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Journal Abstract Search

126 related items for PubMed ID: 14610229

  • 1. Targeted disruption of the olfactory mucosa-specific Cyp2g1 gene: impact on acetaminophen toxicity in the lateral nasal gland, and tissue-selective effects on Cyp2a5 expression.
    Zhuo X, Gu J, Behr MJ, Swiatek PJ, Cui H, Zhang QY, Xie Y, Collins DN, Ding X.
    J Pharmacol Exp Ther; 2004 Feb; 308(2):719-28. PubMed ID: 14610229
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  • 2. Purification and characterization of heterologously expressed mouse CYP2A5 and CYP2G1: role in metabolic activation of acetaminophen and 2,6-dichlorobenzonitrile in mouse olfactory mucosal microsomes.
    Gu J, Zhang QY, Genter MB, Lipinskas TW, Negishi M, Nebert DW, Ding X.
    J Pharmacol Exp Ther; 1998 Jun; 285(3):1287-95. PubMed ID: 9618435
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  • 3. Role of CYP2A5 and 2G1 in acetaminophen metabolism and toxicity in the olfactory mucosa of the Cyp1a2(-/-) mouse.
    Genter MB, Liang HC, Gu J, Ding X, Negishi M, McKinnon RA, Nebert DW.
    Biochem Pharmacol; 1998 Jun 01; 55(11):1819-26. PubMed ID: 9714300
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  • 4. A novel defensive mechanism against acetaminophen toxicity in the mouse lateral nasal gland: role of CYP2A5-mediated regulation of testosterone homeostasis and salivary androgen-binding protein expression.
    Zhou X, Wei Y, Xie F, Laukaitis CM, Karn RC, Kluetzman K, Gu J, Zhang QY, Roberts DW, Ding X.
    Mol Pharmacol; 2011 Apr 01; 79(4):710-23. PubMed ID: 21252290
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  • 9. Mechanisms of olfactory toxicity of the herbicide 2,6-dichlorobenzonitrile: essential roles of CYP2A5 and target-tissue metabolic activation.
    Xie F, Zhou X, Behr M, Fang C, Horii Y, Gu J, Kannan K, Ding X.
    Toxicol Appl Pharmacol; 2010 Nov 15; 249(1):101-6. PubMed ID: 20840855
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  • 11. Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model.
    Zhou X, Zhuo X, Xie F, Kluetzman K, Shu YZ, Humphreys WG, Ding X.
    J Pharmacol Exp Ther; 2010 Feb 15; 332(2):578-87. PubMed ID: 19923441
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  • 12. Respective roles of CYP2A5 and CYP2F2 in the bioactivation of 3-methylindole in mouse olfactory mucosa and lung: studies using Cyp2a5-null and Cyp2f2-null mouse models.
    Zhou X, D'Agostino J, Li L, Moore CD, Yost GS, Ding X.
    Drug Metab Dispos; 2012 Apr 15; 40(4):642-7. PubMed ID: 22228748
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  • 13. Differential xenobiotic induction of CYP2A5 in mouse liver, kidney, lung, and olfactory mucosa.
    Su T, He W, Gu J, Lipinskas TW, Ding X.
    Drug Metab Dispos; 1998 Aug 15; 26(8):822-4. PubMed ID: 9698299
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  • 14. Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2a6: role in metabolic activation of nasal toxicants.
    Liu C, Zhuo X, Gonzalez FJ, Ding X.
    Mol Pharmacol; 1996 Oct 15; 50(4):781-8. PubMed ID: 8863822
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  • 15. Nasal cytochrome P450 2A: identification, regional localization, and metabolic activity toward hexamethylphosphoramide, a known nasal carcinogen.
    Thornton-Manning JR, Nikula KJ, Hotchkiss JA, Avila KJ, Rohrbacher KD, Ding X, Dahl AR.
    Toxicol Appl Pharmacol; 1997 Jan 15; 142(1):22-30. PubMed ID: 9007030
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  • 16. Cytochrome P450 and steroid hydroxylase activity in mouse olfactory and vomeronasal mucosa.
    Gu J, Dudley C, Su T, Spink DC, Zhang QY, Moss RL, Ding X.
    Biochem Biophys Res Commun; 1999 Dec 09; 266(1):262-7. PubMed ID: 10581200
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  • 17. Cell-specific expression of CYP2A5 in the mouse respiratory tract: effects of olfactory toxicants.
    Piras E, Franzén A, Fernández EL, Bergström U, Raffalli-Mathieu F, Lang M, Brittebo EB.
    J Histochem Cytochem; 2003 Nov 09; 51(11):1545-55. PubMed ID: 14566026
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  • 18. Expression of CYP2A genes in rodent and human nasal mucosa.
    Su T, Sheng JJ, Lipinskas TW, Ding X.
    Drug Metab Dispos; 1996 Aug 09; 24(8):884-90. PubMed ID: 8869824
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  • 19. Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas.
    Miyazaki M, Yamazaki H, Takeuchi H, Saoo K, Yokohira M, Masumura K, Nohmi T, Funae Y, Imaida K, Kamataki T.
    Carcinogenesis; 2005 Nov 09; 26(11):1947-55. PubMed ID: 15958517
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  • 20. Mouse cyp2g1 gene: promoter structure and tissue-specific expression of a cyp2g1-lacz fusion gene in transgenic mice.
    Zhuo X, Schwob JE, Swiatek PJ, Ding X.
    Arch Biochem Biophys; 2001 Jul 01; 391(1):127-36. PubMed ID: 11414693
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