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251 related items for PubMed ID: 14612410

  • 1. Increased malignancy of Neu-induced mammary tumors overexpressing active transforming growth factor beta1.
    Muraoka RS, Koh Y, Roebuck LR, Sanders ME, Brantley-Sieders D, Gorska AE, Moses HL, Arteaga CL.
    Mol Cell Biol; 2003 Dec; 23(23):8691-703. PubMed ID: 14612410
    [Abstract] [Full Text] [Related]

  • 2. Investigation of three new mouse mammary tumor cell lines as models for transforming growth factor (TGF)-beta and Neu pathway signaling studies: identification of a novel model for TGF-beta-induced epithelial-to-mesenchymal transition.
    Lenferink AE, Magoon J, Cantin C, O'Connor-McCourt MD.
    Breast Cancer Res; 2004 Dec; 6(5):R514-30. PubMed ID: 15318933
    [Abstract] [Full Text] [Related]

  • 3. Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice.
    Lenferink AE, Simpson JF, Shawver LK, Coffey RJ, Forbes JT, Arteaga CL.
    Proc Natl Acad Sci U S A; 2000 Aug 15; 97(17):9609-14. PubMed ID: 10931950
    [Abstract] [Full Text] [Related]

  • 4. Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors.
    Muraoka-Cook RS, Kurokawa H, Koh Y, Forbes JT, Roebuck LR, Barcellos-Hoff MH, Moody SE, Chodosh LA, Arteaga CL.
    Cancer Res; 2004 Dec 15; 64(24):9002-11. PubMed ID: 15604265
    [Abstract] [Full Text] [Related]

  • 5. Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis.
    Siegel PM, Shu W, Cardiff RD, Muller WJ, Massagué J.
    Proc Natl Acad Sci U S A; 2003 Jul 08; 100(14):8430-5. PubMed ID: 12808151
    [Abstract] [Full Text] [Related]

  • 6. Signaling through ShcA is required for transforming growth factor beta- and Neu/ErbB-2-induced breast cancer cell motility and invasion.
    Northey JJ, Chmielecki J, Ngan E, Russo C, Annis MG, Muller WJ, Siegel PM.
    Mol Cell Biol; 2008 May 08; 28(10):3162-76. PubMed ID: 18332126
    [Abstract] [Full Text] [Related]

  • 7. Gene expression profiling of cancer progression reveals intrinsic regulation of transforming growth factor-beta signaling in ErbB2/Neu-induced tumors from transgenic mice.
    Landis MD, Seachrist DD, Montañez-Wiscovich ME, Danielpour D, Keri RA.
    Oncogene; 2005 Aug 04; 24(33):5173-90. PubMed ID: 15897883
    [Abstract] [Full Text] [Related]

  • 8. Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.
    Muraoka RS, Dumont N, Ritter CA, Dugger TC, Brantley DM, Chen J, Easterly E, Roebuck LR, Ryan S, Gotwals PJ, Koteliansky V, Arteaga CL.
    J Clin Invest; 2002 Jun 04; 109(12):1551-9. PubMed ID: 12070302
    [Abstract] [Full Text] [Related]

  • 9. Transgenic mice expressing a dominant-negative mutant type II transforming growth factor-beta receptor exhibit impaired mammary development and enhanced mammary tumor formation.
    Gorska AE, Jensen RA, Shyr Y, Aakre ME, Bhowmick NA, Moses HL.
    Am J Pathol; 2003 Oct 04; 163(4):1539-49. PubMed ID: 14507660
    [Abstract] [Full Text] [Related]

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  • 11. CdGAP is required for transforming growth factor β- and Neu/ErbB-2-induced breast cancer cell motility and invasion.
    He Y, Northey JJ, Primeau M, Machado RD, Trembath R, Siegel PM, Lamarche-Vane N.
    Oncogene; 2011 Mar 03; 30(9):1032-45. PubMed ID: 21042277
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  • 13. p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.
    Cabodi S, Tinnirello A, Di Stefano P, Bisarò B, Ambrosino E, Castellano I, Sapino A, Arisio R, Cavallo F, Forni G, Glukhova M, Silengo L, Altruda F, Turco E, Tarone G, Defilippi P.
    Cancer Res; 2006 May 01; 66(9):4672-80. PubMed ID: 16651418
    [Abstract] [Full Text] [Related]

  • 14. Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis.
    Labbé E, Lock L, Letamendia A, Gorska AE, Gryfe R, Gallinger S, Moses HL, Attisano L.
    Cancer Res; 2007 Jan 01; 67(1):75-84. PubMed ID: 17210685
    [Abstract] [Full Text] [Related]

  • 15. Over-expression of erbB-2/neu is paralleled by inhibition of mouse-mammary-epithelial-cell differentiation and developmental apoptosis.
    Lazar H, Baltzer A, Gimmi C, Marti A, Jaggi R.
    Int J Cancer; 2000 Feb 15; 85(4):578-83. PubMed ID: 10699933
    [Abstract] [Full Text] [Related]

  • 16. An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial-mesenchymal transition.
    Park CY, Min KN, Son JY, Park SY, Nam JS, Kim DK, Sheen YY.
    Cancer Lett; 2014 Aug 28; 351(1):72-80. PubMed ID: 24887560
    [Abstract] [Full Text] [Related]

  • 17. Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis.
    Novitskiy SV, Forrester E, Pickup MW, Gorska AE, Chytil A, Aakre M, Polosukhina D, Owens P, Yusupova DR, Zhao Z, Ye F, Shyr Y, Moses HL.
    Breast Cancer Res; 2014 Oct 04; 16(5):425. PubMed ID: 25280532
    [Abstract] [Full Text] [Related]

  • 18. Estrogen receptor-beta mediates the protective effects of aromatase induction in the MMTV-Her-2/neu x aromatase double transgenic mice.
    Nair HB, Perla RP, Kirma NB, Krishnegowda NK, Ganapathy M, Rajhans R, Nair SS, Saikumar P, Vadlamudi RK, Tekmal RR.
    Horm Cancer; 2012 Apr 04; 3(1-2):26-36. PubMed ID: 22006184
    [Abstract] [Full Text] [Related]

  • 19. In vitro and in vivo antisense-mediated growth inhibition of a mammary adenocarcinoma from MMTV-neu transgenic mice.
    Sacco MG, Barbieri O, Piccini D, Noviello E, Zoppé M, Zucchi I, Frattini A, Villa A, Vezzoni P.
    Gene Ther; 1998 Mar 04; 5(3):388-93. PubMed ID: 9614559
    [Abstract] [Full Text] [Related]

  • 20. Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression.
    Heckman-Stoddard BM, Vargo-Gogola T, McHenry PR, Jiang V, Herrick MP, Hilsenbeck SG, Settleman J, Rosen JM.
    Breast Cancer Res; 2009 Mar 04; 11(4):R61. PubMed ID: 19703301
    [Abstract] [Full Text] [Related]

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