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780 related items for PubMed ID: 14621997

  • 1. Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity.
    Zhang Y, Swaminathan GJ, Deshpande A, Boix E, Natesh R, Xie Z, Acharya KR, Brew K.
    Biochemistry; 2003 Nov 25; 42(46):13512-21. PubMed ID: 14621997
    [Abstract] [Full Text] [Related]

  • 2. Conformational changes induced by binding UDP-2F-galactose to alpha-1,3 galactosyltransferase- implications for catalysis.
    Jamaluddin H, Tumbale P, Withers SG, Acharya KR, Brew K.
    J Mol Biol; 2007 Jun 22; 369(5):1270-81. PubMed ID: 17493636
    [Abstract] [Full Text] [Related]

  • 3. Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase.
    Zhang Y, Deshpande A, Xie Z, Natesh R, Acharya KR, Brew K.
    Glycobiology; 2004 Dec 22; 14(12):1295-302. PubMed ID: 15229192
    [Abstract] [Full Text] [Related]

  • 4. Structural basis of UDP-galactose binding by alpha-1,3-galactosyltransferase (alpha3GT): role of negative charge on aspartic acid 316 in structure and activity.
    Tumbale P, Jamaluddin H, Thiyagarajan N, Brew K, Acharya KR.
    Biochemistry; 2008 Aug 19; 47(33):8711-8. PubMed ID: 18651752
    [Abstract] [Full Text] [Related]

  • 5. Crystal structure of beta1,4-galactosyltransferase complex with UDP-Gal reveals an oligosaccharide acceptor binding site.
    Ramakrishnan B, Balaji PV, Qasba PK.
    J Mol Biol; 2002 Apr 26; 318(2):491-502. PubMed ID: 12051854
    [Abstract] [Full Text] [Related]

  • 6. Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs.
    Persson K, Ly HD, Dieckelmann M, Wakarchuk WW, Withers SG, Strynadka NC.
    Nat Struct Biol; 2001 Feb 26; 8(2):166-75. PubMed ID: 11175908
    [Abstract] [Full Text] [Related]

  • 7. Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I.
    Ramakrishnan B, Qasba PK.
    J Mol Biol; 2001 Jun 29; 310(1):205-18. PubMed ID: 11419947
    [Abstract] [Full Text] [Related]

  • 8. Comparison of the closed conformation of the beta 1,4-galactosyltransferase-1 (beta 4Gal-T1) in the presence and absence of alpha-lactalbumin (LA).
    Ramakrishnan B, Qasba PK.
    J Biomol Struct Dyn; 2003 Aug 29; 21(1):1-8. PubMed ID: 12854954
    [Abstract] [Full Text] [Related]

  • 9. Screening a limited structure-based library identifies UDP-GalNAc-specific mutants of alpha-1,3-galactosyltransferase.
    Tumbale P, Jamaluddin H, Thiyagarajan N, Acharya KR, Brew K.
    Glycobiology; 2008 Dec 29; 18(12):1036-43. PubMed ID: 18782853
    [Abstract] [Full Text] [Related]

  • 10. Crystal structures of the bovine beta4galactosyltransferase catalytic domain and its complex with uridine diphosphogalactose.
    Gastinel LN, Cambillau C, Bourne Y.
    EMBO J; 1999 Jul 01; 18(13):3546-57. PubMed ID: 10393171
    [Abstract] [Full Text] [Related]

  • 11. Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose.
    Ramakrishnan B, Boeggeman E, Qasba PK.
    Biochemistry; 2004 Oct 05; 43(39):12513-22. PubMed ID: 15449940
    [Abstract] [Full Text] [Related]

  • 12. Binding of an acceptor substrate analog enhances the enzymatic activity of human blood group B galactosyltransferase.
    Sindhuwinata N, Munoz E, Munoz FJ, Palcic MM, Peters H, Peters T.
    Glycobiology; 2010 Jun 05; 20(6):718-23. PubMed ID: 20154292
    [Abstract] [Full Text] [Related]

  • 13. Blood group B galactosyltransferase: insights into substrate binding from NMR experiments.
    Angulo J, Langpap B, Blume A, Biet T, Meyer B, Krishna NR, Peters H, Palcic MM, Peters T.
    J Am Chem Soc; 2006 Oct 18; 128(41):13529-38. PubMed ID: 17031966
    [Abstract] [Full Text] [Related]

  • 14. Amino-acid substitution in the disordered loop of blood group B-glycosyltransferase enzyme causes weak B phenotype.
    Yazer MH, Denomme GA, Rose NL, Palcic MM.
    Transfusion; 2005 Jul 18; 45(7):1178-82. PubMed ID: 15987364
    [Abstract] [Full Text] [Related]

  • 15. Crystal structures of β-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding.
    Tsutsui Y, Ramakrishnan B, Qasba PK.
    J Biol Chem; 2013 Nov 01; 288(44):31963-70. PubMed ID: 24052259
    [Abstract] [Full Text] [Related]

  • 16. Structural basis of ordered binding of donor and acceptor substrates to the retaining glycosyltransferase, alpha-1,3-galactosyltransferase.
    Boix E, Zhang Y, Swaminathan GJ, Brew K, Acharya KR.
    J Biol Chem; 2002 Aug 02; 277(31):28310-8. PubMed ID: 12011052
    [Abstract] [Full Text] [Related]

  • 17. Protein NMR Studies of Substrate Binding to Human Blood Group A and B Glycosyltransferases.
    Grimm LL, Weissbach S, Flügge F, Begemann N, Palcic MM, Peters T.
    Chembiochem; 2017 Jul 04; 18(13):1260-1269. PubMed ID: 28256109
    [Abstract] [Full Text] [Related]

  • 18. Specificity and mechanism of metal ion activation in UDP-galactose:beta -galactoside-alpha -1,3-galactosyltransferase.
    Zhang Y, Wang PG, Brew K.
    J Biol Chem; 2001 Apr 13; 276(15):11567-74. PubMed ID: 11133981
    [Abstract] [Full Text] [Related]

  • 19. Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli.
    Thoden JB, Hegeman AD, Wesenberg G, Chapeau MC, Frey PA, Holden HM.
    Biochemistry; 1997 May 27; 36(21):6294-304. PubMed ID: 9174344
    [Abstract] [Full Text] [Related]

  • 20. Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues.
    Chad JM, Sarathy KP, Gruber TD, Addala E, Kiessling LL, Sanders DA.
    Biochemistry; 2007 Jun 12; 46(23):6723-32. PubMed ID: 17511471
    [Abstract] [Full Text] [Related]

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