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804 related items for PubMed ID: 14626450

  • 1. Selective inhibition of vascular endothelial growth factor receptor-2 (VEGFR-2) identifies a central role for VEGFR-2 in human aortic endothelial cell responses to VEGF.
    Endo A, Fukuhara S, Masuda M, Ohmori T, Mochizuki N.
    J Recept Signal Transduct Res; 2003; 23(2-3):239-54. PubMed ID: 14626450
    [Abstract] [Full Text] [Related]

  • 2. Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS).
    Tanimoto T, Jin ZG, Berk BC.
    J Biol Chem; 2002 Nov 08; 277(45):42997-3001. PubMed ID: 12226078
    [Abstract] [Full Text] [Related]

  • 3. Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide.
    Bussolati B, Dunk C, Grohman M, Kontos CD, Mason J, Ahmed A.
    Am J Pathol; 2001 Sep 08; 159(3):993-1008. PubMed ID: 11549592
    [Abstract] [Full Text] [Related]

  • 4. Phosphorylation of tyrosine 801 of vascular endothelial growth factor receptor-2 is necessary for Akt-dependent endothelial nitric-oxide synthase activation and nitric oxide release from endothelial cells.
    Blanes MG, Oubaha M, Rautureau Y, Gratton JP.
    J Biol Chem; 2007 Apr 06; 282(14):10660-9. PubMed ID: 17303569
    [Abstract] [Full Text] [Related]

  • 5. ZM323881, a novel inhibitor of vascular endothelial growth factor-receptor-2 tyrosine kinase activity.
    Whittles CE, Pocock TM, Wedge SR, Kendrew J, Hennequin LF, Harper SJ, Bates DO.
    Microcirculation; 2002 Dec 06; 9(6):513-22. PubMed ID: 12483548
    [Abstract] [Full Text] [Related]

  • 6. Vascular endothelial growth factor governs endothelial nitric-oxide synthase expression via a KDR/Flk-1 receptor and a protein kinase C signaling pathway.
    Shen BQ, Lee DY, Zioncheck TF.
    J Biol Chem; 1999 Nov 12; 274(46):33057-63. PubMed ID: 10551875
    [Abstract] [Full Text] [Related]

  • 7. Vascular endothelial growth factor acts through novel, pregnancy-enhanced receptor signalling pathways to stimulate endothelial nitric oxide synthase activity in uterine artery endothelial cells.
    Grummer MA, Sullivan JA, Magness RR, Bird IM.
    Biochem J; 2009 Jan 15; 417(2):501-11. PubMed ID: 18816248
    [Abstract] [Full Text] [Related]

  • 8. Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells.
    Chou MT, Wang J, Fujita DJ.
    BMC Biochem; 2002 Dec 31; 3():32. PubMed ID: 12509223
    [Abstract] [Full Text] [Related]

  • 9. Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells.
    Jin ZG, Wong C, Wu J, Berk BC.
    J Biol Chem; 2005 Apr 01; 280(13):12305-9. PubMed ID: 15665327
    [Abstract] [Full Text] [Related]

  • 10. Essential role of calcium in vascular endothelial growth factor A-induced signaling: mechanism of the antiangiogenic effect of carboxyamidotriazole.
    Faehling M, Kroll J, Föhr KJ, Fellbrich G, Mayr U, Trischler G, Waltenberger J.
    FASEB J; 2002 Nov 01; 16(13):1805-7. PubMed ID: 12354692
    [Abstract] [Full Text] [Related]

  • 11. Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants.
    Gille H, Kowalski J, Li B, LeCouter J, Moffat B, Zioncheck TF, Pelletier N, Ferrara N.
    J Biol Chem; 2001 Feb 02; 276(5):3222-30. PubMed ID: 11058584
    [Abstract] [Full Text] [Related]

  • 12. Hepatocyte growth factor stimulates nitric oxide production through endothelial nitric oxide synthase activation by the phosphoinositide 3-kinase/Akt pathway and possibly by mitogen-activated protein kinase kinase in vascular endothelial cells.
    Uruno A, Sugawara A, Kanatsuka H, Arima S, Taniyama Y, Kudo M, Takeuchi K, Ito S.
    Hypertens Res; 2004 Nov 02; 27(11):887-95. PubMed ID: 15824471
    [Abstract] [Full Text] [Related]

  • 13. The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis.
    Heckman CA, Holopainen T, Wirzenius M, Keskitalo S, Jeltsch M, Ylä-Herttuala S, Wedge SR, Jürgensmeier JM, Alitalo K.
    Cancer Res; 2008 Jun 15; 68(12):4754-62. PubMed ID: 18559522
    [Abstract] [Full Text] [Related]

  • 14. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation.
    Gerber HP, McMurtrey A, Kowalski J, Yan M, Keyt BA, Dixit V, Ferrara N.
    J Biol Chem; 1998 Nov 13; 273(46):30336-43. PubMed ID: 9804796
    [Abstract] [Full Text] [Related]

  • 15. Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1.
    Landgren E, Schiller P, Cao Y, Claesson-Welsh L.
    Oncogene; 1998 Jan 22; 16(3):359-67. PubMed ID: 9467961
    [Abstract] [Full Text] [Related]

  • 16. Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells.
    Kanno S, Oda N, Abe M, Terai Y, Ito M, Shitara K, Tabayashi K, Shibuya M, Sato Y.
    Oncogene; 2000 Apr 20; 19(17):2138-46. PubMed ID: 10815805
    [Abstract] [Full Text] [Related]

  • 17. Caveolin-1 expression is critical for vascular endothelial growth factor-induced ischemic hindlimb collateralization and nitric oxide-mediated angiogenesis.
    Sonveaux P, Martinive P, DeWever J, Batova Z, Daneau G, Pelat M, Ghisdal P, Grégoire V, Dessy C, Balligand JL, Feron O.
    Circ Res; 2004 Jul 23; 95(2):154-61. PubMed ID: 15205364
    [Abstract] [Full Text] [Related]

  • 18. Chronic hypoxia attenuates VEGF signaling and angiogenic responses by downregulation of KDR in human endothelial cells.
    Olszewska-Pazdrak B, Hein TW, Olszewska P, Carney DH.
    Am J Physiol Cell Physiol; 2009 May 23; 296(5):C1162-70. PubMed ID: 19244479
    [Abstract] [Full Text] [Related]

  • 19. Assessing the activity of cediranib, a VEGFR-2/3 tyrosine kinase inhibitor, against VEGFR-1 and members of the structurally related PDGFR family.
    Brave SR, Ratcliffe K, Wilson Z, James NH, Ashton S, Wainwright A, Kendrew J, Dudley P, Broadbent N, Sproat G, Taylor S, Barnes C, Silva JC, Farnsworth CL, Hennequin L, Ogilvie DJ, Jürgensmeier JM, Shibuya M, Wedge SR, Barry ST.
    Mol Cancer Ther; 2011 May 23; 10(5):861-73. PubMed ID: 21441409
    [Abstract] [Full Text] [Related]

  • 20. Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase.
    Jin ZG, Ueba H, Tanimoto T, Lungu AO, Frame MD, Berk BC.
    Circ Res; 2003 Aug 22; 93(4):354-63. PubMed ID: 12893742
    [Abstract] [Full Text] [Related]

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