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Journal Abstract Search


205 related items for PubMed ID: 14634213

  • 1. P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1.
    Asher G, Lotem J, Tsvetkov P, Reiss V, Sachs L, Shaul Y.
    Proc Natl Acad Sci U S A; 2003 Dec 09; 100(25):15065-70. PubMed ID: 14634213
    [Abstract] [Full Text] [Related]

  • 2. Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1.
    Asher G, Lotem J, Sachs L, Kahana C, Shaul Y.
    Proc Natl Acad Sci U S A; 2002 Oct 01; 99(20):13125-30. PubMed ID: 12232053
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.
    Tsvetkov P, Asher G, Reiss V, Shaul Y, Sachs L, Lotem J.
    Proc Natl Acad Sci U S A; 2005 Apr 12; 102(15):5535-40. PubMed ID: 15809436
    [Abstract] [Full Text] [Related]

  • 4. The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol.
    Asher G, Dym O, Tsvetkov P, Adler J, Shaul Y.
    Biochemistry; 2006 May 23; 45(20):6372-8. PubMed ID: 16700548
    [Abstract] [Full Text] [Related]

  • 5. 20S proteasomal degradation of ornithine decarboxylase is regulated by NQO1.
    Asher G, Bercovich Z, Tsvetkov P, Shaul Y, Kahana C.
    Mol Cell; 2005 Mar 04; 17(5):645-55. PubMed ID: 15749015
    [Abstract] [Full Text] [Related]

  • 6. NQO1 stabilizes p53 through a distinct pathway.
    Asher G, Lotem J, Kama R, Sachs L, Shaul Y.
    Proc Natl Acad Sci U S A; 2002 Mar 05; 99(5):3099-104. PubMed ID: 11867746
    [Abstract] [Full Text] [Related]

  • 7. NRH:quinone oxidoreductase 2 and NAD(P)H:quinone oxidoreductase 1 protect tumor suppressor p53 against 20s proteasomal degradation leading to stabilization and activation of p53.
    Gong X, Kole L, Iskander K, Jaiswal AK.
    Cancer Res; 2007 Jun 01; 67(11):5380-8. PubMed ID: 17545619
    [Abstract] [Full Text] [Related]

  • 8. Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation.
    Rodriguez MS, Desterro JM, Lain S, Lane DP, Hay RT.
    Mol Cell Biol; 2000 Nov 01; 20(22):8458-67. PubMed ID: 11046142
    [Abstract] [Full Text] [Related]

  • 9. A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73.
    Asher G, Tsvetkov P, Kahana C, Shaul Y.
    Genes Dev; 2005 Feb 01; 19(3):316-21. PubMed ID: 15687255
    [Abstract] [Full Text] [Related]

  • 10. Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1.
    Asher G, Lotem J, Cohen B, Sachs L, Shaul Y.
    Proc Natl Acad Sci U S A; 2001 Jan 30; 98(3):1188-93. PubMed ID: 11158615
    [Abstract] [Full Text] [Related]

  • 11. DNA damage-induced MDMX degradation is mediated by MDM2.
    Kawai H, Wiederschain D, Kitao H, Stuart J, Tsai KK, Yuan ZM.
    J Biol Chem; 2003 Nov 14; 278(46):45946-53. PubMed ID: 12963717
    [Abstract] [Full Text] [Related]

  • 12. MDM2 can promote the ubiquitination, nuclear export, and degradation of p53 in the absence of direct binding.
    Inoue T, Geyer RK, Howard D, Yu ZK, Maki CG.
    J Biol Chem; 2001 Nov 30; 276(48):45255-60. PubMed ID: 11572869
    [Abstract] [Full Text] [Related]

  • 13. p53 proteasomal degradation: poly-ubiquitination is not the whole story.
    Asher G, Shaul Y.
    Cell Cycle; 2005 Aug 30; 4(8):1015-8. PubMed ID: 16082197
    [Abstract] [Full Text] [Related]

  • 14. Dicoumarol sensitizes renal cell carcinoma Caki cells to TRAIL-induced apoptosis through down-regulation of Bcl-2, Mcl-1 and c-FLIP in a NQO1-independent manner.
    Park EJ, Min KJ, Choi KS, Kwon TK.
    Exp Cell Res; 2014 Apr 15; 323(1):144-154. PubMed ID: 24462458
    [Abstract] [Full Text] [Related]

  • 15. Dicoumarol enhances gemcitabine-induced cytotoxicity in high NQO1-expressing cholangiocarcinoma cells.
    Buranrat B, Prawan A, Kukongviriyapan U, Kongpetch S, Kukongviriyapan V.
    World J Gastroenterol; 2010 May 21; 16(19):2362-70. PubMed ID: 20480521
    [Abstract] [Full Text] [Related]

  • 16. MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts.
    Gentiletti F, Mancini F, D'Angelo M, Sacchi A, Pontecorvi A, Jochemsen AG, Moretti F.
    Oncogene; 2002 Jan 31; 21(6):867-77. PubMed ID: 11840332
    [Abstract] [Full Text] [Related]

  • 17. Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cells.
    Ahn HJ, Kim KS, Shin KW, Lim KH, Kim JO, Lee JY, Kim J, Park JH, Yang KM, Baek KH, Ko JJ, Park KS.
    Oncotarget; 2015 Dec 29; 6(42):44523-37. PubMed ID: 26540344
    [Abstract] [Full Text] [Related]

  • 18. MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation.
    Jin Y, Lee H, Zeng SX, Dai MS, Lu H.
    EMBO J; 2003 Dec 01; 22(23):6365-77. PubMed ID: 14633995
    [Abstract] [Full Text] [Related]

  • 19. Negative Cooperativity in NAD(P)H Quinone Oxidoreductase 1 (NQO1).
    Megarity CF, Abdel-Aal Bettley H, Caraher MC, Scott KA, Whitehead RC, Jowitt TA, Gutierrez A, Bryce RA, Nolan KA, Stratford IJ, Timson DJ.
    Chembiochem; 2019 Nov 18; 20(22):2841-2849. PubMed ID: 31165578
    [Abstract] [Full Text] [Related]

  • 20. Stability and ubiquitination of the tumor suppressor protein p53.
    Jardine LJ, Maki CG.
    Methods Mol Biol; 2003 Nov 18; 223():27-38. PubMed ID: 12777718
    [No Abstract] [Full Text] [Related]


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