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Journal Abstract Search

438 related items for PubMed ID: 14640553

  • 1. Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists.
    Kitbunnadaj R, Zuiderveld OP, De Esch IJ, Vollinga RC, Bakker R, Lutz M, Spek AL, Cavoy E, Deltent MF, Menge WM, Timmerman H, Leurs R.
    J Med Chem; 2003 Dec 04; 46(25):5445-57. PubMed ID: 14640553
    [Abstract] [Full Text] [Related]

  • 2. Identification of 4-(1H-imidazol-4(5)-ylmethyl)pyridine (immethridine) as a novel, potent, and highly selective histamine H(3) receptor agonist.
    Kitbunnadaj R, Zuiderveld OP, Christophe B, Hulscher S, Menge WM, Gelens E, Snip E, Bakker RA, Celanire S, Gillard M, Talaga P, Timmerman H, Leurs R.
    J Med Chem; 2004 May 06; 47(10):2414-7. PubMed ID: 15115383
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  • 3. Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.
    Watanabe M, Kazuta Y, Hayashi H, Yamada S, Matsuda A, Shuto S.
    J Med Chem; 2006 Sep 07; 49(18):5587-96. PubMed ID: 16942032
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  • 4. N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist.
    Kitbunnadaj R, Hashimoto T, Poli E, Zuiderveld OP, Menozzi A, Hidaka R, de Esch IJ, Bakker RA, Menge WM, Yamatodani A, Coruzzi G, Timmerman H, Leurs R.
    J Med Chem; 2005 Mar 24; 48(6):2100-7. PubMed ID: 15771452
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  • 5. Investigation of the histamine H3 receptor binding site. Design and synthesis of hybrid agonists with a lipophilic side chain.
    Ishikawa M, Watanabe T, Kudo T, Yokoyama F, Yamauchi M, Kato K, Kakui N, Sato Y.
    J Med Chem; 2010 Sep 09; 53(17):6445-56. PubMed ID: 20690643
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  • 6. Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.
    Kovalainen JT, Christiaans JA, Kotisaari S, Laitinen JT, Männistö PT, Tuomisto L, Gynther J.
    J Med Chem; 1999 Apr 08; 42(7):1193-202. PubMed ID: 10197963
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  • 7. Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.
    Kazuta Y, Hirano K, Natsume K, Yamada S, Kimura R, Matsumoto S, Furuichi K, Matsuda A, Shuto S.
    J Med Chem; 2003 May 08; 46(10):1980-8. PubMed ID: 12723960
    [Abstract] [Full Text] [Related]

  • 8. A selective human H(4)-receptor agonist: (-)-2-cyano-1-methyl-3-[(2R,5R)-5- [1H-imidazol-4(5)-yl]tetrahydrofuran-2-y] methylguanidine.
    Hashimoto T, Harusawa S, Araki L, Zuiderveld OP, Smit MJ, Imazu T, Takashima S, Yamamoto Y, Sakamoto Y, Kurihara T, Leurs R, Bakker RA, Yamatodani A.
    J Med Chem; 2003 Jul 03; 46(14):3162-5. PubMed ID: 12825954
    [Abstract] [Full Text] [Related]

  • 9. Agonist/antagonist modulation in a series of 2-aryl benzimidazole H4 receptor ligands.
    Savall BM, Edwards JP, Venable JD, Buzard DJ, Thurmond R, Hack M, McGovern P.
    Bioorg Med Chem Lett; 2010 Jun 01; 20(11):3367-71. PubMed ID: 20452213
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  • 10. Synthesis and functional characterization of imbutamine analogs as histamine H3 and H4 receptor ligands.
    Geyer R, Kaske M, Baumeister P, Buschauer A.
    Arch Pharm (Weinheim); 2014 Feb 01; 347(2):77-88. PubMed ID: 24493592
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  • 17. Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.
    Pelloux-Léon N, Fkyerat A, Piripitsi A, Tertiuk W, Schunack W, Stark H, Garbarg M, Ligneau X, Arrang JM, Schwartz JC, Ganellin CR.
    J Med Chem; 2004 Jun 03; 47(12):3264-74. PubMed ID: 15163206
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