These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

692 related items for PubMed ID: 14640560

  • 1. Synthesis and evaluation of nitroheterocyclic carbamate prodrugs for use with nitroreductase-mediated gene-directed enzyme prodrug therapy.
    Hay MP, Anderson RF, Ferry DM, Wilson WR, Denny WA.
    J Med Chem; 2003 Dec 04; 46(25):5533-45. PubMed ID: 14640560
    [Abstract] [Full Text] [Related]

  • 2. Structure-activity relationships for 4-nitrobenzyl carbamates of 5-aminobenz[e]indoline minor groove alkylating agents as prodrugs for GDEPT in conjunction with E. coli nitroreductase.
    Hay MP, Atwell GJ, Wilson WR, Pullen SM, Denny WA.
    J Med Chem; 2003 Jun 05; 46(12):2456-66. PubMed ID: 12773049
    [Abstract] [Full Text] [Related]

  • 3.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 4. Synthesis and structure-activity relationships for 2,4-dinitrobenzamide-5-mustards as prodrugs for the Escherichia coli nfsB nitroreductase in gene therapy.
    Atwell GJ, Yang S, Pruijn FB, Pullen SM, Hogg A, Patterson AV, Wilson WR, Denny WA.
    J Med Chem; 2007 Mar 22; 50(6):1197-212. PubMed ID: 17326614
    [Abstract] [Full Text] [Related]

  • 5. Aziridinyldinitrobenzamides: synthesis and structure-activity relationships for activation by E. coli nitroreductase.
    Helsby NA, Atwell GJ, Yang S, Palmer BD, Anderson RF, Pullen SM, Ferry DM, Hogg A, Wilson WR, Denny WA.
    J Med Chem; 2004 Jun 03; 47(12):3295-307. PubMed ID: 15163209
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, and biological evaluation of cyclic and acyclic nitrobenzylphosphoramide mustards for E. coli nitroreductase activation.
    Jiang Y, Han J, Yu C, Vass SO, Searle PF, Browne P, Knox RJ, Hu L.
    J Med Chem; 2006 Jul 13; 49(14):4333-43. PubMed ID: 16821793
    [Abstract] [Full Text] [Related]

  • 7. Self-immolative nitrogen mustard prodrugs for suicide gene therapy.
    Niculescu-Duvaz D, Niculescu-Duvaz I, Friedlos F, Martin J, Spooner R, Davies L, Marais R, Springer CJ.
    J Med Chem; 1998 Dec 17; 41(26):5297-309. PubMed ID: 9857097
    [Abstract] [Full Text] [Related]

  • 8. Quantitation of bystander effects in nitroreductase suicide gene therapy using three-dimensional cell cultures.
    Wilson WR, Pullen SM, Hogg A, Helsby NA, Hicks KO, Denny WA.
    Cancer Res; 2002 Mar 01; 62(5):1425-32. PubMed ID: 11888915
    [Abstract] [Full Text] [Related]

  • 9. A 2-nitroimidazole carbamate prodrug of 5-amimo-1-(chloromethyl)-3-[(5,6,7-trimethoxyindol-2-yl)carbony l]-1,2-dihydro-3H--benz[E]indole (amino-seco-CBI-TMI) for use with ADEPT and GDEPT.
    Hay MP, Sykes BM, Denny WA, Wilson WR.
    Bioorg Med Chem Lett; 1999 Aug 02; 9(15):2237-42. PubMed ID: 10465553
    [Abstract] [Full Text] [Related]

  • 10.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 11. Testing double mutants of the enzyme nitroreductase for enhanced cell sensitisation to prodrugs: effects of combining beneficial single mutations.
    Jaberipour M, Vass SO, Guise CP, Grove JI, Knox RJ, Hu L, Hyde EI, Searle PF.
    Biochem Pharmacol; 2010 Jan 15; 79(2):102-11. PubMed ID: 19665450
    [Abstract] [Full Text] [Related]

  • 12. Virus directed enzyme prodrug therapy for ovarian and pancreatic cancer using retrovirally delivered E. coli nitroreductase and CB1954.
    McNeish IA, Green NK, Gilligan MG, Ford MJ, Mautner V, Young LS, Kerr DJ, Searle PF.
    Gene Ther; 1998 Aug 15; 5(8):1061-9. PubMed ID: 10326029
    [Abstract] [Full Text] [Related]

  • 13.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 14. 5-Amino-1-(chloromethyl)-1,2-dihydro-3H-benz[e]indoles: relationships between structure and cytotoxicity for analogues bearing different DNA minor groove binding subunits.
    Atwell GJ, Milbank JJ, Wilson WR, Hogg A, Denny WA.
    J Med Chem; 1999 Aug 26; 42(17):3400-11. PubMed ID: 10464026
    [Abstract] [Full Text] [Related]

  • 15. Virus-directed enzyme prodrug therapy using CB1954.
    Grove JI, Searle PF, Weedon SJ, Green NK, McNeish IA, Kerr DJ.
    Anticancer Drug Des; 1999 Dec 26; 14(6):461-72. PubMed ID: 10834268
    [Abstract] [Full Text] [Related]

  • 16.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 17. Combined adenovirus-mediated nitroreductase gene delivery and CB1954 treatment: a well-tolerated therapy for established solid tumors.
    Djeha AH, Thomson TA, Leung H, Searle PF, Young LS, Kerr DJ, Harris PA, Mountain A, Wrighton CJ.
    Mol Ther; 2001 Feb 26; 3(2):233-40. PubMed ID: 11237680
    [Abstract] [Full Text] [Related]

  • 18. Discovery and evaluation of Escherichia coli nitroreductases that activate the anti-cancer prodrug CB1954.
    Prosser GA, Copp JN, Syddall SP, Williams EM, Smaill JB, Wilson WR, Patterson AV, Ackerley DF.
    Biochem Pharmacol; 2010 Mar 01; 79(5):678-87. PubMed ID: 19852945
    [Abstract] [Full Text] [Related]

  • 19.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 20. Investigation of alternative prodrugs for use with E. coli nitroreductase in 'suicide gene' approaches to cancer therapy.
    Bailey SM, Knox RJ, Hobbs SM, Jenkins TC, Mauger AB, Melton RG, Burke PJ, Connors TA, Hart IR.
    Gene Ther; 1996 Dec 01; 3(12):1143-50. PubMed ID: 8986441
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 35.