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340 related items for PubMed ID: 14647471

  • 1. Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24.
    Lebedeva IV, Sarkar D, Su ZZ, Kitada S, Dent P, Stein CA, Reed JC, Fisher PB.
    Oncogene; 2003 Nov 27; 22(54):8758-73. PubMed ID: 14647471
    [Abstract] [Full Text] [Related]

  • 2. Ionizing radiation enhances therapeutic activity of mda-7/IL-24: overcoming radiation- and mda-7/IL-24-resistance in prostate cancer cells overexpressing the antiapoptotic proteins bcl-xL or bcl-2.
    Su ZZ, Lebedeva IV, Sarkar D, Emdad L, Gupta P, Kitada S, Dent P, Reed JC, Fisher PB.
    Oncogene; 2006 Apr 13; 25(16):2339-48. PubMed ID: 16331261
    [Abstract] [Full Text] [Related]

  • 3. Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.
    Lebedeva IV, Su ZZ, Sarkar D, Kitada S, Dent P, Waxman S, Reed JC, Fisher PB.
    Cancer Res; 2003 Dec 01; 63(23):8138-44. PubMed ID: 14678967
    [Abstract] [Full Text] [Related]

  • 4. Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells.
    Su Z, Emdad L, Sauane M, Lebedeva IV, Sarkar D, Gupta P, James CD, Randolph A, Valerie K, Walter MR, Dent P, Fisher PB.
    Oncogene; 2005 Nov 17; 24(51):7552-66. PubMed ID: 16044151
    [Abstract] [Full Text] [Related]

  • 5. The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells.
    Lebedeva IV, Su ZZ, Chang Y, Kitada S, Reed JC, Fisher PB.
    Oncogene; 2002 Jan 24; 21(5):708-18. PubMed ID: 11850799
    [Abstract] [Full Text] [Related]

  • 6. Prostate-specific expression of Bax delivered by an adenoviral vector induces apoptosis in LNCaP prostate cancer cells.
    Lowe SL, Rubinchik S, Honda T, McDonnell TJ, Dong JY, Norris JS.
    Gene Ther; 2001 Sep 24; 8(18):1363-71. PubMed ID: 11571575
    [Abstract] [Full Text] [Related]

  • 7. Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation-associated -7 (mda-7)/interleukin-24 (IL-24) gene.
    Saito Y, Miyahara R, Gopalan B, Litvak A, Inoue S, Shanker M, Branch CD, Mhashilkar AM, Roth JA, Chada S, Ramesh R.
    Cancer Gene Ther; 2005 Mar 24; 12(3):238-47. PubMed ID: 15578066
    [Abstract] [Full Text] [Related]

  • 8. Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.
    Huang EY, Madireddi MT, Gopalkrishnan RV, Leszczyniecka M, Su Z, Lebedeva IV, Kang D, Jiang H, Lin JJ, Alexandre D, Chen Y, Vozhilla N, Mei MX, Christiansen KA, Sivo F, Goldstein NI, Mhashilkar AB, Chada S, Huberman E, Pestka S, Fisher PB.
    Oncogene; 2001 Oct 25; 20(48):7051-63. PubMed ID: 11704829
    [Abstract] [Full Text] [Related]

  • 9. Tumor-suppressive effects by adenovirus-mediated mda-7 gene transfer in non-small cell lung cancer cell in vitro.
    Saeki T, Mhashilkar A, Chada S, Branch C, Roth JA, Ramesh R.
    Gene Ther; 2000 Dec 25; 7(23):2051-7. PubMed ID: 11175318
    [Abstract] [Full Text] [Related]

  • 10. Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis.
    Hemmati PG, Gillissen B, von Haefen C, Wendt J, Stärck L, Güner D, Dörken B, Daniel PT.
    Oncogene; 2002 May 09; 21(20):3149-61. PubMed ID: 12082630
    [Abstract] [Full Text] [Related]

  • 11. Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis.
    Aranha O, Grignon R, Fernandes N, McDonnell TJ, Wood DP, Sarkar FH.
    Int J Oncol; 2003 Apr 09; 22(4):787-94. PubMed ID: 12632069
    [Abstract] [Full Text] [Related]

  • 12. Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
    Su ZZ, Lebedeva IV, Sarkar D, Gopalkrishnan RV, Sauane M, Sigmon C, Yacoub A, Valerie K, Dent P, Fisher PB.
    Oncogene; 2003 Feb 27; 22(8):1164-80. PubMed ID: 12606943
    [Abstract] [Full Text] [Related]

  • 13. Adenovirus vector expressing mda-7 selectively kills hepatocellular carcinoma cell line Hep3B.
    Xue XB, Chen K, Wang CJ, Zheng JW, Yu Y, Peng ZH, Wu ZD.
    Hepatobiliary Pancreat Dis Int; 2008 Oct 27; 7(5):509-14. PubMed ID: 18842498
    [Abstract] [Full Text] [Related]

  • 14. Adenovirus-mediated Bax overexpression for the induction of therapeutic apoptosis in prostate cancer.
    Li X, Marani M, Yu J, Nan B, Roth JA, Kagawa S, Fang B, Denner L, Marcelli M.
    Cancer Res; 2001 Jan 01; 61(1):186-91. PubMed ID: 11196158
    [Abstract] [Full Text] [Related]

  • 15. Targeting inhibition of K-ras enhances Ad.mda-7-induced growth suppression and apoptosis in mutant K-ras colorectal cancer cells.
    Lebedeva IV, Su ZZ, Emdad L, Kolomeyer A, Sarkar D, Kitada S, Waxman S, Reed JC, Fisher PB.
    Oncogene; 2007 Feb 01; 26(5):733-44. PubMed ID: 16924242
    [Abstract] [Full Text] [Related]

  • 16. Extended survivability of prostate cancer cells in the absence of trophic factors: increased proliferation, evasion of apoptosis, and the role of apoptosis proteins.
    Tang DG, Li L, Chopra DP, Porter AT.
    Cancer Res; 1998 Aug 01; 58(15):3466-79. PubMed ID: 9699682
    [Abstract] [Full Text] [Related]

  • 17. Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis.
    Lebedeva IV, Su ZZ, Sarkar D, Gopalkrishnan RV, Waxman S, Yacoub A, Dent P, Fisher PB.
    Oncogene; 2005 Jan 20; 24(4):585-96. PubMed ID: 15580305
    [Abstract] [Full Text] [Related]

  • 18. Adenovirus-mediated mda-7 gene expression radiosensitizes non-small cell lung cancer cells via TP53-independent mechanisms.
    Kawabe S, Nishikawa T, Munshi A, Roth JA, Chada S, Meyn RE.
    Mol Ther; 2002 Nov 20; 6(5):637-44. PubMed ID: 12409262
    [Abstract] [Full Text] [Related]

  • 19. A comprehensive assessment of p53-responsive genes following adenoviral-p53 gene transfer in Bcl-2-expressing prostate cancer cells.
    Spurgers KB, Coombes KR, Meyn RE, Gold DL, Logothetis CJ, Johnson TJ, McDonnell TJ.
    Oncogene; 2004 Mar 04; 23(9):1712-23. PubMed ID: 14647426
    [Abstract] [Full Text] [Related]

  • 20. Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo.
    Raffo AJ, Perlman H, Chen MW, Day ML, Streitman JS, Buttyan R.
    Cancer Res; 1995 Oct 01; 55(19):4438-45. PubMed ID: 7671257
    [Abstract] [Full Text] [Related]


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