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Journal Abstract Search

356 related items for PubMed ID: 14649209

  • 1. Protein tyrosine phosphatase 1B inhibitors for the treatment of type 2 diabetes and obesity: recent advances.
    Harley EA, Levens N.
    Curr Opin Investig Drugs; 2003 Oct; 4(10):1179-89. PubMed ID: 14649209
    [Abstract] [Full Text] [Related]

  • 2. Protein tyrosine phosphatase 1B as a target for the treatment of impaired glucose tolerance and type II diabetes.
    Liu G, Trevillyan JM.
    Curr Opin Investig Drugs; 2002 Nov; 3(11):1608-16. PubMed ID: 12476961
    [Abstract] [Full Text] [Related]

  • 3. Protein tyrosine phosphatase 1B inhibitors for diabetes.
    Johnson TO, Ermolieff J, Jirousek MR.
    Nat Rev Drug Discov; 2002 Sep; 1(9):696-709. PubMed ID: 12209150
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus.
    Koren S, Fantus IG.
    Best Pract Res Clin Endocrinol Metab; 2007 Dec; 21(4):621-40. PubMed ID: 18054739
    [Abstract] [Full Text] [Related]

  • 5. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery.
    Zhang S, Zhang ZY.
    Drug Discov Today; 2007 May; 12(9-10):373-81. PubMed ID: 17467573
    [Abstract] [Full Text] [Related]

  • 6. Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control.
    Popov D.
    Biochem Biophys Res Commun; 2011 Jul 08; 410(3):377-81. PubMed ID: 21683066
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of protein tyrosine phosphatase 1B by ursane-type triterpenes isolated from Symplocos paniculata.
    Na M, Yang S, He L, Oh H, Kim BS, Oh WK, Kim BY, Ahn JS.
    Planta Med; 2006 Feb 08; 72(3):261-3. PubMed ID: 16534732
    [Abstract] [Full Text] [Related]

  • 8. In silico structure-based design of a potent and selective small peptide inhibitor of protein tyrosine phosphatase 1B, a novel therapeutic target for obesity and type 2 diabetes mellitus: a computer modeling approach.
    Rao GS, Ramachandran MV, Bajaj JS.
    J Biomol Struct Dyn; 2006 Feb 08; 23(4):377-84. PubMed ID: 16363874
    [Abstract] [Full Text] [Related]

  • 9. Recent advances in the development of small molecule inhibitors of PTP1B for the treatment of insulin resistance and type 2 diabetes.
    Tobin JF, Tam S.
    Curr Opin Drug Discov Devel; 2002 Jul 08; 5(4):500-12. PubMed ID: 12197308
    [Abstract] [Full Text] [Related]

  • 10. Targeting protein tyrosine phosphatase to enhance insulin action for the potential treatment of diabetes.
    Kasibhatla B, Wos J, Peters KG.
    Curr Opin Investig Drugs; 2007 Oct 08; 8(10):805-13. PubMed ID: 17907056
    [Abstract] [Full Text] [Related]

  • 11. Synthesis of functionalized acetophenones as protein tyrosine phosphatase 1B inhibitors.
    Dixit M, Tripathi BK, Srivastava AK, Goel A.
    Bioorg Med Chem Lett; 2005 Jul 15; 15(14):3394-7. PubMed ID: 15951172
    [Abstract] [Full Text] [Related]

  • 12. The structural basis for the selectivity of benzotriazole inhibitors of PTP1B.
    Scapin G, Patel SB, Becker JW, Wang Q, Desponts C, Waddleton D, Skorey K, Cromlish W, Bayly C, Therien M, Gauthier JY, Li CS, Lau CK, Ramachandran C, Kennedy BP, Asante-Appiah E.
    Biochemistry; 2003 Oct 07; 42(39):11451-9. PubMed ID: 14516196
    [Abstract] [Full Text] [Related]

  • 13. Protein-tyrosine phosphatase 1B (PTP1B): a novel therapeutic target for type 2 diabetes mellitus, obesity and related states of insulin resistance.
    Goldstein BJ.
    Curr Drug Targets Immune Endocr Metabol Disord; 2001 Nov 07; 1(3):265-75. PubMed ID: 12477292
    [Abstract] [Full Text] [Related]

  • 14. Methylenedisalicylic acid derivatives: new PTP1B inhibitors that confer resistance to diet-induced obesity.
    Shrestha S, Bhattarai BR, Chang KJ, Lee KH, Cho H.
    Bioorg Med Chem Lett; 2007 May 15; 17(10):2760-4. PubMed ID: 17368023
    [Abstract] [Full Text] [Related]

  • 15. Development of a robust scintillation proximity assay for protein tyrosine phosphatase 1B using the catalytically inactive (C215S) mutant.
    Skorey KI, Kennedy BP, Friesen RW, Ramachandran C.
    Anal Biochem; 2001 Apr 15; 291(2):269-78. PubMed ID: 11401301
    [Abstract] [Full Text] [Related]

  • 16. Cellular inhibition of protein tyrosine phosphatase 1B by uncharged thioxothiazolidinone derivatives.
    Stuible M, Zhao L, Aubry I, Schmidt-Arras D, Böhmer FD, Li CJ, Tremblay ML.
    Chembiochem; 2007 Jan 22; 8(2):179-86. PubMed ID: 17191286
    [Abstract] [Full Text] [Related]

  • 17. [Does inhibition of tyrosine phosphatase 1B protect from obesity and type 2 diabetes?].
    Ukkola O, Santaniemi M.
    Duodecim; 2002 Jan 22; 118(18):1857-62. PubMed ID: 12422667
    [No Abstract] [Full Text] [Related]

  • 18. Inhibition of protein tyrosine phosphatase 1B by lignans from Myristica fragrans.
    Yang S, Na MK, Jang JP, Kim KA, Kim BY, Sung NJ, Oh WK, Ahn JS.
    Phytother Res; 2006 Aug 22; 20(8):680-2. PubMed ID: 16752372
    [Abstract] [Full Text] [Related]

  • 19. Prospects for inhibitors of protein tyrosine phosphatase 1B as antidiabetic drugs.
    Hooft van Huijsduijnen R, Sauer WH, Bombrun A, Swinnen D.
    J Med Chem; 2004 Aug 12; 47(17):4142-6. PubMed ID: 15293983
    [No Abstract] [Full Text] [Related]

  • 20. Dammaranes from Gynostemma pentaphyllum and synthesis of their derivatives as inhibitors of protein tyrosine phosphatase 1B.
    Xu JQ, Shen Q, Li J, Hu LH.
    Bioorg Med Chem; 2010 Jun 01; 18(11):3934-9. PubMed ID: 20472439
    [Abstract] [Full Text] [Related]

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