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174 related items for PubMed ID: 14661061

  • 1. SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization.
    Ismail IH, Mårtensson S, Moshinsky D, Rice A, Tang C, Howlett A, McMahon G, Hammarsten O.
    Oncogene; 2004 Jan 29; 23(4):873-82. PubMed ID: 14661061
    [Abstract] [Full Text] [Related]

  • 2. Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks.
    Chernikova SB, Wells RL, Elkind MM.
    Radiat Res; 1999 Feb 29; 151(2):159-66. PubMed ID: 9952300
    [Abstract] [Full Text] [Related]

  • 3. A targeted inhibition of DNA-dependent protein kinase sensitizes breast cancer cells following ionizing radiation.
    Kim CH, Park SJ, Lee SH.
    J Pharmacol Exp Ther; 2002 Nov 29; 303(2):753-9. PubMed ID: 12388662
    [Abstract] [Full Text] [Related]

  • 4. Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.
    Veuger SJ, Curtin NJ, Richardson CJ, Smith GC, Durkacz BW.
    Cancer Res; 2003 Sep 15; 63(18):6008-15. PubMed ID: 14522929
    [Abstract] [Full Text] [Related]

  • 5. Interactive competition between homologous recombination and non-homologous end joining.
    Allen C, Halbrook J, Nickoloff JA.
    Mol Cancer Res; 2003 Oct 15; 1(12):913-20. PubMed ID: 14573792
    [Abstract] [Full Text] [Related]

  • 6. [DNA-dependent protein kinase: a major protein involved in the cellular response to ionizing radiation].
    Muller C, Rodrigo G, Calsou P, Salles B.
    Bull Cancer; 1999 Dec 15; 86(12):977-83. PubMed ID: 10660692
    [Abstract] [Full Text] [Related]

  • 7. Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.
    Wang H, Zeng ZC, Bui TA, DiBiase SJ, Qin W, Xia F, Powell SN, Iliakis G.
    Cancer Res; 2001 Jan 01; 61(1):270-7. PubMed ID: 11196174
    [Abstract] [Full Text] [Related]

  • 8. DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs.
    Shinohara ET, Geng L, Tan J, Chen H, Shir Y, Edwards E, Halbrook J, Kesicki EA, Kashishian A, Hallahan DE.
    Cancer Res; 2005 Jun 15; 65(12):4987-92. PubMed ID: 15958537
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.
    Sarkaria JN, Tibbetts RS, Busby EC, Kennedy AP, Hill DE, Abraham RT.
    Cancer Res; 1998 Oct 01; 58(19):4375-82. PubMed ID: 9766667
    [Abstract] [Full Text] [Related]

  • 10. Threonines 2638/2647 in DNA-PK are essential for cellular resistance to ionizing radiation.
    Soubeyrand S, Pope L, Pakuts B, Haché RJ.
    Cancer Res; 2003 Mar 15; 63(6):1198-201. PubMed ID: 12649176
    [Abstract] [Full Text] [Related]

  • 11. Potentiation of chlorambucil cytotoxicity in B-cell chronic lymphocytic leukemia by inhibition of DNA-dependent protein kinase activity using wortmannin.
    Christodoulopoulos G, Muller C, Salles B, Kazmi R, Panasci L.
    Cancer Res; 1998 May 01; 58(9):1789-92. PubMed ID: 9581813
    [Abstract] [Full Text] [Related]

  • 12. Selective inactivation of DNA-dependent protein kinase with antisense oligodeoxynucleotides: consequences for the rejoining of radiation-induced DNA double-strand breaks and radiosensitivity of human cancer cell lines.
    Sak A, Stuschke M, Wurm R, Schroeder G, Sinn B, Wolf G, Budach V.
    Cancer Res; 2002 Nov 15; 62(22):6621-4. PubMed ID: 12438258
    [Abstract] [Full Text] [Related]

  • 13. Interaction of DNA-dependent protein kinase and poly(ADP-ribose) polymerase with radiation-induced DNA strand breaks.
    Weinfeld M, Chaudhry MA, D'Amours D, Pelletier JD, Poirier GG, Povirk LF, Lees-Miller SP.
    Radiat Res; 1997 Jul 15; 148(1):22-8. PubMed ID: 9216614
    [Abstract] [Full Text] [Related]

  • 14. Backup pathways of NHEJ are suppressed by DNA-PK.
    Perrault R, Wang H, Wang M, Rosidi B, Iliakis G.
    J Cell Biochem; 2004 Jul 01; 92(4):781-94. PubMed ID: 15211575
    [Abstract] [Full Text] [Related]

  • 15. Trifluoperazine stimulates ionizing radiation induced cell killing through inhibition of DNA repair.
    Gangopadhyay S, Karmakar P, Dasgupta U, Chakraborty A.
    Mutat Res; 2007 Oct 04; 633(2):117-25. PubMed ID: 17627868
    [Abstract] [Full Text] [Related]

  • 16. The DNA repair complex DNA-PK, a pharmacological target in cancer chemotherapy and radiotherapy.
    Salles B, Calsou P, Frit P, Muller C.
    Pathol Biol (Paris); 2006 May 04; 54(4):185-93. PubMed ID: 16563661
    [Abstract] [Full Text] [Related]

  • 17. [Repair of ionizing radiation induced DNA double strand breaks].
    Widłak P.
    Postepy Hig Med Dosw; 2000 May 04; 54(2):133-48. PubMed ID: 10857377
    [Abstract] [Full Text] [Related]

  • 18. Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries.
    Leahy JJ, Golding BT, Griffin RJ, Hardcastle IR, Richardson C, Rigoreau L, Smith GC.
    Bioorg Med Chem Lett; 2004 Dec 20; 14(24):6083-7. PubMed ID: 15546735
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of hsp90 compromises the DNA damage response to radiation.
    Dote H, Burgan WE, Camphausen K, Tofilon PJ.
    Cancer Res; 2006 Sep 15; 66(18):9211-20. PubMed ID: 16982765
    [Abstract] [Full Text] [Related]

  • 20. Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells.
    Okayasu R, Suetomi K, Ullrich RL.
    Radiat Res; 1998 May 15; 149(5):440-5. PubMed ID: 9588354
    [Abstract] [Full Text] [Related]

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