These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. Structures of ceftazidime and its transition-state analogue in complex with AmpC beta-lactamase: implications for resistance mutations and inhibitor design. Powers RA, Caselli E, Focia PJ, Prati F, Shoichet BK. Biochemistry; 2001 Aug 07; 40(31):9207-14. PubMed ID: 11478888 [Abstract] [Full Text] [Related]
23. Insights into positive and negative requirements for protein-protein interactions by crystallographic analysis of the beta-lactamase inhibitory proteins BLIP, BLIP-I, and BLP. Gretes M, Lim DC, de Castro L, Jensen SE, Kang SG, Lee KJ, Strynadka NC. J Mol Biol; 2009 Jun 05; 389(2):289-305. PubMed ID: 19332077 [Abstract] [Full Text] [Related]
24. 4-Substituted trinems as broad spectrum beta-lactamase inhibitors: structure-based design, synthesis, and biological activity. Plantan I, Selic L, Mesar T, Anderluh PS, Oblak M, Prezelj A, Hesse L, Andrejasic M, Vilar M, Turk D, Kocijan A, Prevec T, Vilfan G, Kocjan D, Copar A, Urleb U, Solmajer T. J Med Chem; 2007 Aug 23; 50(17):4113-21. PubMed ID: 17665896 [Abstract] [Full Text] [Related]
25. Thermodynamic evaluation of a covalently bonded transition state analogue inhibitor: inhibition of beta-lactamases by phosphonates. Nagarajan R, Pratt RF. Biochemistry; 2004 Aug 03; 43(30):9664-73. PubMed ID: 15274621 [Abstract] [Full Text] [Related]
26. Crystal structures of the class D beta-lactamase OXA-13 in the native form and in complex with meropenem. Pernot L, Frénois F, Rybkine T, L'Hermite G, Petrella S, Delettré J, Jarlier V, Collatz E, Sougakoff W. J Mol Biol; 2001 Jul 20; 310(4):859-74. PubMed ID: 11453693 [Abstract] [Full Text] [Related]
27. Mechanism of the reaction catalyzed by isoaspartyl dipeptidase from Escherichia coli. Martí-Arbona R, Fresquet V, Thoden JB, Davis ML, Holden HM, Raushel FM. Biochemistry; 2005 May 17; 44(19):7115-24. PubMed ID: 15882050 [Abstract] [Full Text] [Related]
28. Crystal structure of an acylation transition-state analog of the TEM-1 beta-lactamase. Mechanistic implications for class A beta-lactamases. Maveyraud L, Pratt RF, Samama JP. Biochemistry; 1998 Feb 24; 37(8):2622-8. PubMed ID: 9485412 [Abstract] [Full Text] [Related]
29. Binding hot spots in the TEM1-BLIP interface in light of its modular architecture. Reichmann D, Cohen M, Abramovich R, Dym O, Lim D, Strynadka NC, Schreiber G. J Mol Biol; 2007 Jan 19; 365(3):663-79. PubMed ID: 17070843 [Abstract] [Full Text] [Related]
30. Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism. Xu Y, Nakajima Y, Ito K, Zheng H, Oyama H, Heiser U, Hoffmann T, Gärtner UT, Demuth HU, Yoshimoto T. J Mol Biol; 2008 Jan 18; 375(3):708-19. PubMed ID: 18042490 [Abstract] [Full Text] [Related]
31. Unanticipated inhibition of the metallo-beta-lactamase from Bacteroides fragilis by 4-morpholineethanesulfonic acid (MES): a crystallographic study at 1.85-A resolution. Fitzgerald PM, Wu JK, Toney JH. Biochemistry; 1998 May 12; 37(19):6791-800. PubMed ID: 9578564 [Abstract] [Full Text] [Related]
32. Binding of D- and L-captopril inhibitors to metallo-beta-lactamase studied by polarizable molecular mechanics and quantum mechanics. Antony J, Gresh N, Olsen L, Hemmingsen L, Schofield CJ, Bauer R. J Comput Chem; 2002 Oct 12; 23(13):1281-96. PubMed ID: 12210153 [Abstract] [Full Text] [Related]
33. Crystal structure of extended-spectrum beta-lactamase Toho-1: insights into the molecular mechanism for catalytic reaction and substrate specificity expansion. Ibuka AS, Ishii Y, Galleni M, Ishiguro M, Yamaguchi K, Frère JM, Matsuzawa H, Sakai H. Biochemistry; 2003 Sep 16; 42(36):10634-43. PubMed ID: 12962487 [Abstract] [Full Text] [Related]
34. Structural determinants of enzyme binding affinity: the E1 component of pyruvate dehydrogenase from Escherichia coli in complex with the inhibitor thiamin thiazolone diphosphate. Arjunan P, Chandrasekhar K, Sax M, Brunskill A, Nemeria N, Jordan F, Furey W. Biochemistry; 2004 Mar 09; 43(9):2405-11. PubMed ID: 14992577 [Abstract] [Full Text] [Related]
35. Biophysical characterization of the interaction of the beta-lactamase TEM-1 with its protein inhibitor BLIP. Albeck S, Schreiber G. Biochemistry; 1999 Jan 05; 38(1):11-21. PubMed ID: 9890878 [Abstract] [Full Text] [Related]
36. Structure of the wild-type TEM-1 beta-lactamase at 1.55 A and the mutant enzyme Ser70Ala at 2.1 A suggest the mode of noncovalent catalysis for the mutant enzyme. Stec B, Holtz KM, Wojciechowski CL, Kantrowitz ER. Acta Crystallogr D Biol Crystallogr; 2005 Aug 05; 61(Pt 8):1072-9. PubMed ID: 16041072 [Abstract] [Full Text] [Related]
37. Inhibition of class A and class C beta-lactamases by penems: crystallographic structures of a novel 1,4-thiazepine intermediate. Nukaga M, Abe T, Venkatesan AM, Mansour TS, Bonomo RA, Knox JR. Biochemistry; 2003 Nov 18; 42(45):13152-9. PubMed ID: 14609325 [Abstract] [Full Text] [Related]
38. Molecular dynamics-solvated interaction energy studies of protein-protein interactions: the MP1-p14 scaffolding complex. Cui Q, Sulea T, Schrag JD, Munger C, Hung MN, Naïm M, Cygler M, Purisima EO. J Mol Biol; 2008 Jun 13; 379(4):787-802. PubMed ID: 18479705 [Abstract] [Full Text] [Related]
39. Structural and thermodynamic study on aldose reductase: nitro-substituted inhibitors with strong enthalpic binding contribution. Steuber H, Heine A, Klebe G. J Mol Biol; 2007 May 04; 368(3):618-38. PubMed ID: 17368668 [Abstract] [Full Text] [Related]
40. Tazobactam forms a stoichiometric trans-enamine intermediate in the E166A variant of SHV-1 beta-lactamase: 1.63 A crystal structure. Padayatti PS, Helfand MS, Totir MA, Carey MP, Hujer AM, Carey PR, Bonomo RA, van den Akker F. Biochemistry; 2004 Feb 03; 43(4):843-8. PubMed ID: 14744126 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]