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179 related items for PubMed ID: 14678967

  • 1. Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.
    Lebedeva IV, Su ZZ, Sarkar D, Kitada S, Dent P, Waxman S, Reed JC, Fisher PB.
    Cancer Res; 2003 Dec 01; 63(23):8138-44. PubMed ID: 14678967
    [Abstract] [Full Text] [Related]

  • 2. Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24.
    Lebedeva IV, Sarkar D, Su ZZ, Kitada S, Dent P, Stein CA, Reed JC, Fisher PB.
    Oncogene; 2003 Nov 27; 22(54):8758-73. PubMed ID: 14647471
    [Abstract] [Full Text] [Related]

  • 3. Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis.
    Lebedeva IV, Su ZZ, Sarkar D, Gopalkrishnan RV, Waxman S, Yacoub A, Dent P, Fisher PB.
    Oncogene; 2005 Jan 20; 24(4):585-96. PubMed ID: 15580305
    [Abstract] [Full Text] [Related]

  • 4. Ionizing radiation enhances therapeutic activity of mda-7/IL-24: overcoming radiation- and mda-7/IL-24-resistance in prostate cancer cells overexpressing the antiapoptotic proteins bcl-xL or bcl-2.
    Su ZZ, Lebedeva IV, Sarkar D, Emdad L, Gupta P, Kitada S, Dent P, Reed JC, Fisher PB.
    Oncogene; 2006 Apr 13; 25(16):2339-48. PubMed ID: 16331261
    [Abstract] [Full Text] [Related]

  • 5. Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation-associated -7 (mda-7)/interleukin-24 (IL-24) gene.
    Saito Y, Miyahara R, Gopalan B, Litvak A, Inoue S, Shanker M, Branch CD, Mhashilkar AM, Roth JA, Chada S, Ramesh R.
    Cancer Gene Ther; 2005 Mar 13; 12(3):238-47. PubMed ID: 15578066
    [Abstract] [Full Text] [Related]

  • 6. Targeting inhibition of K-ras enhances Ad.mda-7-induced growth suppression and apoptosis in mutant K-ras colorectal cancer cells.
    Lebedeva IV, Su ZZ, Emdad L, Kolomeyer A, Sarkar D, Kitada S, Waxman S, Reed JC, Fisher PB.
    Oncogene; 2007 Feb 01; 26(5):733-44. PubMed ID: 16924242
    [Abstract] [Full Text] [Related]

  • 7. Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells.
    Su Z, Emdad L, Sauane M, Lebedeva IV, Sarkar D, Gupta P, James CD, Randolph A, Valerie K, Walter MR, Dent P, Fisher PB.
    Oncogene; 2005 Nov 17; 24(51):7552-66. PubMed ID: 16044151
    [Abstract] [Full Text] [Related]

  • 8. Adenovirus vector expressing mda-7 selectively kills hepatocellular carcinoma cell line Hep3B.
    Xue XB, Chen K, Wang CJ, Zheng JW, Yu Y, Peng ZH, Wu ZD.
    Hepatobiliary Pancreat Dis Int; 2008 Oct 17; 7(5):509-14. PubMed ID: 18842498
    [Abstract] [Full Text] [Related]

  • 9. Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells.
    Gopalan B, Litvak A, Sharma S, Mhashilkar AM, Chada S, Ramesh R.
    Cancer Res; 2005 Apr 15; 65(8):3017-24. PubMed ID: 15833826
    [Abstract] [Full Text] [Related]

  • 10. Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction.
    Seo SK, Lee HC, Woo SH, Jin HO, Yoo DH, Lee SJ, An S, Choe TB, Park MJ, Hong SI, Park IC, Rhee CH.
    Apoptosis; 2007 Jan 15; 12(1):195-209. PubMed ID: 17136320
    [Abstract] [Full Text] [Related]

  • 11. Selective amino acid restriction targets mitochondria to induce apoptosis of androgen-independent prostate cancer cells.
    Fu YM, Zhang H, Ding M, Li YQ, Fu X, Yu ZX, Meadows GG.
    J Cell Physiol; 2006 Nov 15; 209(2):522-34. PubMed ID: 16897757
    [Abstract] [Full Text] [Related]

  • 12. Apigenin drives the production of reactive oxygen species and initiates a mitochondrial mediated cell death pathway in prostate epithelial cells.
    Morrissey C, O'Neill A, Spengler B, Christoffel V, Fitzpatrick JM, Watson RW.
    Prostate; 2005 May 01; 63(2):131-42. PubMed ID: 15486995
    [Abstract] [Full Text] [Related]

  • 13. The role of Ca2+ in baicalein-induced apoptosis in human breast MDA-MB-231 cancer cells through mitochondria- and caspase-3-dependent pathway.
    Lee JH, Li YC, Ip SW, Hsu SC, Chang NW, Tang NY, Yu CS, Chou ST, Lin SS, Lino CC, Yang JS, Chung JG.
    Anticancer Res; 2008 May 01; 28(3A):1701-11. PubMed ID: 18630529
    [Abstract] [Full Text] [Related]

  • 14. The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells.
    Lebedeva IV, Su ZZ, Chang Y, Kitada S, Reed JC, Fisher PB.
    Oncogene; 2002 Jan 24; 21(5):708-18. PubMed ID: 11850799
    [Abstract] [Full Text] [Related]

  • 15. Production of reactive oxygen species and loss of viability in yeast mitochondrial mutants: protective effect of Bcl-xL.
    Trancíková A, Weisová P, Kissová I, Zeman I, Kolarov J.
    FEMS Yeast Res; 2004 Nov 24; 5(2):149-56. PubMed ID: 15489198
    [Abstract] [Full Text] [Related]

  • 16. Adenovirus-mediated mda-7 gene expression radiosensitizes non-small cell lung cancer cells via TP53-independent mechanisms.
    Kawabe S, Nishikawa T, Munshi A, Roth JA, Chada S, Meyn RE.
    Mol Ther; 2002 Nov 24; 6(5):637-44. PubMed ID: 12409262
    [Abstract] [Full Text] [Related]

  • 17. [Effects of adenoviral-mediated melanoma differentiation associated gene-7/IL-24 on growth and apoptosis of breast cancer cells].
    Ni QC, Yang L, Zhang CH, Zhou F, Zhu HJ, Huang JF.
    Zhonghua Yi Xue Za Zhi; 2008 Nov 18; 88(42):3008-11. PubMed ID: 19080082
    [Abstract] [Full Text] [Related]

  • 18. HIV antiretroviral drug combination induces endothelial mitochondrial dysfunction and reactive oxygen species production, but not apoptosis.
    Jiang B, Hebert VY, Li Y, Mathis JM, Alexander JS, Dugas TR.
    Toxicol Appl Pharmacol; 2007 Oct 01; 224(1):60-71. PubMed ID: 17669453
    [Abstract] [Full Text] [Related]

  • 19. mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer.
    Chada S, Bocangel D, Ramesh R, Grimm EA, Mumm JB, Mhashilkar AM, Zheng M.
    Mol Ther; 2005 May 01; 11(5):724-33. PubMed ID: 15851011
    [Abstract] [Full Text] [Related]

  • 20. Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
    Chada S, Mhashilkar AM, Ramesh R, Mumm JB, Sutton RB, Bocangel D, Zheng M, Grimm EA, Ekmekcioglu S.
    Mol Ther; 2004 Dec 01; 10(6):1085-95. PubMed ID: 15564140
    [Abstract] [Full Text] [Related]


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