These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. An experimental cell-based model for studying the cell biology and molecular pharmacology of 5-lipoxygenase-activating protein in leukotriene biosynthesis. Gerstmeier J, Weinigel C, Barz D, Werz O, Garscha U. Biochim Biophys Acta; 2014 Sep; 1840(9):2961-9. PubMed ID: 24905297 [Abstract] [Full Text] [Related]
4. BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly. Garscha U, Voelker S, Pace S, Gerstmeier J, Emini B, Liening S, Rossi A, Weinigel C, Rummler S, Schubert US, Scriba GK, Çelikoğlu E, Çalışkan B, Banoglu E, Sautebin L, Werz O. Biochem Pharmacol; 2016 Nov 01; 119():17-26. PubMed ID: 27592027 [Abstract] [Full Text] [Related]
5. 5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes. Woods JW, Evans JF, Ethier D, Scott S, Vickers PJ, Hearn L, Heibein JA, Charleson S, Singer II. J Exp Med; 1993 Dec 01; 178(6):1935-46. PubMed ID: 8245774 [Abstract] [Full Text] [Related]
6. The molecular mechanism of the inhibition by licofelone of the biosynthesis of 5-lipoxygenase products. Fischer L, Hornig M, Pergola C, Meindl N, Franke L, Tanrikulu Y, Dodt G, Schneider G, Steinhilber D, Werz O. Br J Pharmacol; 2007 Oct 01; 152(4):471-80. PubMed ID: 17704828 [Abstract] [Full Text] [Related]
7. Translocation and leukotriene synthetic capacity of nuclear 5-lipoxygenase in rat basophilic leukemia cells and alveolar macrophages. Brock TG, McNish RW, Peters-Golden M. J Biol Chem; 1995 Sep 15; 270(37):21652-8. PubMed ID: 7665580 [Abstract] [Full Text] [Related]
8. Increases in 5-lipoxygenase activating protein expression account for enhanced capacity for 5-lipoxygenase metabolism that accompanies differentiation of peripheral blood monocytes into alveolar macrophages. Coffey MJ, Wilcoxen SE, Peters-Golden M. Am J Respir Cell Mol Biol; 1994 Aug 15; 11(2):153-8. PubMed ID: 8049076 [Abstract] [Full Text] [Related]
9. 5-lipoxygenase-activating protein stimulates the utilization of arachidonic acid by 5-lipoxygenase. Abramovitz M, Wong E, Cox ME, Richardson CD, Li C, Vickers PJ. Eur J Biochem; 1993 Jul 01; 215(1):105-11. PubMed ID: 8344271 [Abstract] [Full Text] [Related]
11. Leukotriene synthesis in U937 cells expressing recombinant 5-lipoxygenase. Kargman S, Rousseau P, Reid GK, Rouzer CA, Mancini JA, Rands E, Dixon RA, Diehl RE, Léveillé C, Nathaniel D. J Lipid Mediat; 1993 May 01; 7(1):31-45. PubMed ID: 8358023 [Abstract] [Full Text] [Related]
12. Characterization of the interaction of human 5-lipoxygenase with its activating protein FLAP. Häfner AK, Gerstmeier J, Hörnig M, George S, Ball AK, Schröder M, Garscha U, Werz O, Steinhilber D. Biochim Biophys Acta; 2015 Nov 01; 1851(11):1465-72. PubMed ID: 26327594 [Abstract] [Full Text] [Related]
13. Time-resolved in situ assembly of the leukotriene-synthetic 5-lipoxygenase/5-lipoxygenase-activating protein complex in blood leukocytes. Gerstmeier J, Weinigel C, Rummler S, Rådmark O, Werz O, Garscha U. FASEB J; 2016 Jan 01; 30(1):276-85. PubMed ID: 26396238 [Abstract] [Full Text] [Related]
14. Membrane association of active 5-lipoxygenase in resting cells. Evidence for novel regulation of the enzyme in the rat alveolar macrophage. Coffey M, Peters-Golden M, Fantone JC, Sporn PH. J Biol Chem; 1992 Jan 05; 267(1):570-6. PubMed ID: 1309754 [Abstract] [Full Text] [Related]
15. Translocation of HL-60 cell 5-lipoxygenase. Inhibition of A23187- or N-formyl-methionyl-leucyl-phenylalanine-induced translocation by indole and quinoline leukotriene synthesis inhibitors. Kargman S, Prasit P, Evans JF. J Biol Chem; 1991 Dec 15; 266(35):23745-52. PubMed ID: 1748650 [Abstract] [Full Text] [Related]
16. Increased expression of cytosolic phospholipase A2, 5-lipoxygenase and 5-lipoxygenase-activating protein in rat peritoneal macrophages during ovalbumin-induced sensitization. Escoubet-Lozach L, M'Rini C, Rey A, Béraud M, Lepert JC, Courtade M, Frisach MF, Pipy B. Clin Exp Allergy; 2001 Jul 15; 31(7):1094-104. PubMed ID: 11468001 [Abstract] [Full Text] [Related]
17. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Dixon RA, Diehl RE, Opas E, Rands E, Vickers PJ, Evans JF, Gillard JW, Miller DK. Nature; 1990 Jan 18; 343(6255):282-4. PubMed ID: 2300173 [Abstract] [Full Text] [Related]
18. Capacity for repeatable leukotriene generation after transient stimulation of mast cells and macrophages. Brock TG, McNish RW, Peters-Golden M. Biochem J; 1998 Feb 01; 329 ( Pt 3)(Pt 3):519-25. PubMed ID: 9445378 [Abstract] [Full Text] [Related]
19. Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models. Carty TJ, Sweeney FJ, Griffiths RJ, Eskra JD, Ernest MJ, Pillar JS, Cheng JD, Loose LD, Joseph PA, Pazoles PP, Moore PF, Nagahisa A, Murase S, Kadin SB. Inflamm Res; 1997 May 01; 46(5):168-79. PubMed ID: 9197987 [Abstract] [Full Text] [Related]
20. A23187 stimulates translocation of 5-lipoxygenase from cytosol to membrane in human alveolar macrophages. Pueringer RJ, Bahns CC, Monick MM, Hunninghake GW. Am J Physiol; 1992 Apr 01; 262(4 Pt 1):L454-8. PubMed ID: 1314503 [Abstract] [Full Text] [Related] Page: [Next] [New Search]