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Journal Abstract Search

126 related items for PubMed ID: 1469692

  • 1. Novel spirosuccinimides with incorporated isoindolone and benzisothiazole 1,1-dioxide moieties as aldose reductase inhibitors and antihyperglycemic agents.
    Wrobel J, Dietrich A, Woolson SA, Millen J, McCaleb M, Harrison MC, Hohman TC, Sredy J, Sullivan D.
    J Med Chem; 1992 Nov 27; 35(24):4613-27. PubMed ID: 1469692
    [Abstract] [Full Text] [Related]

  • 2. Novel spirosuccinimide aldose reductase inhibitors derived from isoquinoline-1,3-diones: 2-[(4-bromo-2-fluorophenyl)methyl]-6- fluorospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone and congeners. 1.
    Malamas MS, Hohman TC, Millen J.
    J Med Chem; 1994 Jun 24; 37(13):2043-58. PubMed ID: 8027986
    [Abstract] [Full Text] [Related]

  • 3. Syntheses of tolrestat analogues containing additional substituents in the ring and their evaluation as aldose reductase inhibitors. Identification of potent, orally active 2-fluoro derivatives.
    Wrobel J, Millen J, Sredy J, Dietrich A, Gorham BJ, Malamas M, Kelly JM, Bauman JG, Harrison MC, Jones LR.
    J Med Chem; 1991 Aug 24; 34(8):2504-20. PubMed ID: 1908522
    [Abstract] [Full Text] [Related]

  • 4. Antihyperglycemic activity of novel substituted 3H-1,2,3,5-oxathiadiazole 2-oxides.
    Ellinboe JW, Alessi TR, Dolak TM, Nguyen TT, Tomer JD, Guzzo F, Bagli JF, McCaleb ML.
    J Med Chem; 1992 Apr 03; 35(7):1176-83. PubMed ID: 1560432
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and aldose reductase inhibitory activity of 5-arylidene-2,4-thiazolidinediones.
    Bruno G, Costantino L, Curinga C, Maccari R, Monforte F, Nicoló F, Ottanà R, Vigorita MG.
    Bioorg Med Chem; 2002 Apr 03; 10(4):1077-84. PubMed ID: 11836118
    [Abstract] [Full Text] [Related]

  • 6. Acid derivatives of benzisothiazole-1,1-dioxide as inhibitors of rat lens aldose reductase.
    Da Settimo A, Primofiore G, La Motta C, Da Settimo F, Simorini F, Boldrini E, Bianchini P.
    Farmaco; 1996 Apr 03; 51(4):261-7. PubMed ID: 8645413
    [Abstract] [Full Text] [Related]

  • 7. N-substituted spirosuccinimide, spiropyridazine, spiroazetidine, and acetic acid aldose reductase inhibitors derived from isoquinoline-1,3-diones. 2.
    Malamas MS, Hohman TC.
    J Med Chem; 1994 Jun 24; 37(13):2059-70. PubMed ID: 8027987
    [Abstract] [Full Text] [Related]

  • 8. Ciglitazone, a new hypoglycemic agent. I. Studies in ob/ob and db/db mice, diabetic Chinese hamsters, and normal and streptozotocin-diabetic rats.
    Chang AY, Wyse BM, Gilchrist BJ, Peterson T, Diani AR.
    Diabetes; 1983 Sep 24; 32(9):830-8. PubMed ID: 6354790
    [Abstract] [Full Text] [Related]

  • 9. Pharmacokinetics and efficacy of structurally related spirohydantoin and spirosuccinimide aldose reductase inhibitors.
    Park YH, Barker R, Griffin B, Barratt D, DuPriest M, Brazzell K, York B, Mayer P.
    Xenobiotica; 1992 May 24; 22(5):543-50. PubMed ID: 1413869
    [Abstract] [Full Text] [Related]

  • 10. Novel euglycemic and hypolipidemic agents. 1.
    Lohray BB, Bhushan V, Rao BP, Madhavan GR, Murali N, Rao KN, Reddy AK, Rajesh BM, Reddy PG, Chakrabarti R, Vikramadithyan RK, Rajagopalan R, Mamidi RN, Jajoo HK, Subramaniam S.
    J Med Chem; 1998 May 07; 41(10):1619-30. PubMed ID: 9572887
    [Abstract] [Full Text] [Related]

  • 11. Benzisothiazole-1,1-dioxide alkanoic acid derivatives as inhibitors of rat lens aldose reductase.
    Primofiore G, Da Settimo F, La Motta C, Simorini F, Minutolo A, Boldrini E.
    Farmaco; 1997 Oct 07; 52(10):583-8. PubMed ID: 9507669
    [Abstract] [Full Text] [Related]

  • 12. Orally active aldose reductase inhibitors derived from bioisosteric substitutions on tolrestat.
    Wrobel J, Millen J, Sredy J, Dietrich A, Kelly JM, Gorham BJ, Sestanj K.
    J Med Chem; 1989 Nov 07; 32(11):2493-500. PubMed ID: 2509709
    [Abstract] [Full Text] [Related]

  • 13. Novel thiazolidine-2,4-diones as potent euglycemic agents.
    Hulin B, Clark DA, Goldstein SW, McDermott RE, Dambek PJ, Kappeler WH, Lamphere CH, Lewis DM, Rizzi JP.
    J Med Chem; 1992 May 15; 35(10):1853-64. PubMed ID: 1588563
    [Abstract] [Full Text] [Related]

  • 14. Hydantoin bioisosteres. In vivo active spiro hydroxy acetic acid aldose reductase inhibitors.
    Lipinski CA, Aldinger CE, Beyer TA, Bordner J, Burdi DF, Bussolotti DL, Inskeep PB, Siegel TW.
    J Med Chem; 1992 Jun 12; 35(12):2169-77. PubMed ID: 1613744
    [Abstract] [Full Text] [Related]

  • 15. Quantitative structure-activity analysis of 5-arylidene-2,4-thiazolidinediones as aldose reductase inhibitors.
    Sambasivarao SV, Soni LK, Gupta AK, Hanumantharao P, Kaskhedikar SG.
    Bioorg Med Chem Lett; 2006 Feb 12; 16(3):512-20. PubMed ID: 16297625
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and antihyperglycemic activity of novel 5-(naphthalenylsulfonyl)-2,4-thiazolidinediones.
    Zask A, Jirkovsky I, Nowicki JW, McCaleb ML.
    J Med Chem; 1990 May 12; 33(5):1418-23. PubMed ID: 2329563
    [Abstract] [Full Text] [Related]

  • 17. Spiro hydantoin aldose reductase inhibitors.
    Sarges R, Schnur RC, Belletire JL, Peterson MJ.
    J Med Chem; 1988 Jan 12; 31(1):230-43. PubMed ID: 3121857
    [Abstract] [Full Text] [Related]

  • 18. Perfluorocarbon-based antidiabetic agents.
    Kees KL, Smith TM, McCaleb ML, Prozialeck DH, Cheeseman RS, Christos TE, Patt WC, Steiner KE.
    J Med Chem; 1992 Mar 06; 35(5):944-53. PubMed ID: 1548684
    [Abstract] [Full Text] [Related]

  • 19. Antihyperglycemic activity of new 1,2,4-oxadiazolidine-3,5-diones.
    Malamas MS, Sredy J, McCaleb M, Gunawan I, Mihan B, Sullivan D.
    Eur J Med Chem; 2001 Jan 06; 36(1):31-42. PubMed ID: 11231047
    [Abstract] [Full Text] [Related]

  • 20. Substituted 2-thioxothiazolidin-4-one derivatives showed protective effects against diabetic cataract via inhibition of aldose reductase.
    Huang W, Zhang Y, Liang X, Yang L.
    Arch Pharm (Weinheim); 2020 Jun 06; 353(6):e1900371. PubMed ID: 32237167
    [Abstract] [Full Text] [Related]

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