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455 related items for PubMed ID: 14709545

  • 1. Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway.
    Lee JT, Xu J, Lee JM, Ku G, Han X, Yang DI, Chen S, Hsu CY.
    J Cell Biol; 2004 Jan 05; 164(1):123-31. PubMed ID: 14709545
    [Abstract] [Full Text] [Related]

  • 2. Amyloid-beta peptide enhances tumor necrosis factor-alpha-induced iNOS through neutral sphingomyelinase/ceramide pathway in oligodendrocytes.
    Zeng C, Lee JT, Chen H, Chen S, Hsu CY, Xu J.
    J Neurochem; 2005 Aug 05; 94(3):703-12. PubMed ID: 16033420
    [Abstract] [Full Text] [Related]

  • 3. Amyloid beta peptide increases DP5 expression via activation of neutral sphingomyelinase and JNK in oligodendrocytes.
    Chen S, Lee JM, Zeng C, Chen H, Hsu CY, Xu J.
    J Neurochem; 2006 May 05; 97(3):631-40. PubMed ID: 16524368
    [Abstract] [Full Text] [Related]

  • 4. Soluble oligomers of amyloid-beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway.
    Malaplate-Armand C, Florent-Béchard S, Youssef I, Koziel V, Sponne I, Kriem B, Leininger-Muller B, Olivier JL, Oster T, Pillot T.
    Neurobiol Dis; 2006 Jul 05; 23(1):178-89. PubMed ID: 16626961
    [Abstract] [Full Text] [Related]

  • 5. Neutral sphingomyelinase activation in endothelial and glial cell death induced by amyloid beta-peptide.
    Yang DI, Yeh CH, Chen S, Xu J, Hsu CY.
    Neurobiol Dis; 2004 Oct 05; 17(1):99-107. PubMed ID: 15350970
    [Abstract] [Full Text] [Related]

  • 6. The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase.
    Lei X, Zhang S, Bohrer A, Bao S, Song H, Ramanadham S.
    Biochemistry; 2007 Sep 04; 46(35):10170-85. PubMed ID: 17685585
    [Abstract] [Full Text] [Related]

  • 7. Peptidoglycan induces cyclooxygenase-2 expression in macrophages by activating the neutral sphingomyelinase-ceramide pathway.
    Chen BC, Chang HM, Hsu MJ, Shih CM, Chiu YH, Chiu WT, Lin CH.
    J Biol Chem; 2009 Jul 31; 284(31):20562-73. PubMed ID: 19531467
    [Abstract] [Full Text] [Related]

  • 8. Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease.
    Jana A, Pahan K.
    J Biol Chem; 2004 Dec 03; 279(49):51451-9. PubMed ID: 15452132
    [Abstract] [Full Text] [Related]

  • 9. Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease.
    Jana A, Pahan K.
    J Neurosci; 2010 Sep 22; 30(38):12676-89. PubMed ID: 20861373
    [Abstract] [Full Text] [Related]

  • 10. Ceramide generation during curcumin-induced apoptosis is controlled by crosstalk among Bcl-2, Bcl-xL, caspases and glutathione.
    Abdel Shakor AB, Atia M, Alshehri AS, Sobota A, Kwiatkowska K.
    Cell Signal; 2015 Nov 22; 27(11):2220-30. PubMed ID: 26232616
    [Abstract] [Full Text] [Related]

  • 11. Mitochondrial mechanisms in amyloid beta peptide-induced cerebrovascular degeneration.
    Hsu MJ, Sheu JR, Lin CH, Shen MY, Hsu CY.
    Biochim Biophys Acta; 2010 Mar 22; 1800(3):290-6. PubMed ID: 19698762
    [Abstract] [Full Text] [Related]

  • 12. Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease.
    Cutler RG, Kelly J, Storie K, Pedersen WA, Tammara A, Hatanpaa K, Troncoso JC, Mattson MP.
    Proc Natl Acad Sci U S A; 2004 Feb 17; 101(7):2070-5. PubMed ID: 14970312
    [Abstract] [Full Text] [Related]

  • 13. Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ Accumulation.
    Jazvinšćak Jembrek M, Hof PR, Šimić G.
    Oxid Med Cell Longev; 2015 Feb 17; 2015():346783. PubMed ID: 26090071
    [Abstract] [Full Text] [Related]

  • 14. Amyloid-beta peptides are cytotoxic to oligodendrocytes.
    Xu J, Chen S, Ahmed SH, Chen H, Ku G, Goldberg MP, Hsu CY.
    J Neurosci; 2001 Jan 01; 21(1):RC118. PubMed ID: 11150354
    [Abstract] [Full Text] [Related]

  • 15. Human placenta sphingomyelinase, an exogenous acidic pH-optimum sphingomyelinase, induces oxidative stress, glutathione depletion, and apoptosis in rat hepatocytes.
    García-Ruiz C, Marí M, Morales A, Colell A, Ardite E, Fernández-Checa JC.
    Hepatology; 2000 Jul 01; 32(1):56-65. PubMed ID: 10869289
    [Abstract] [Full Text] [Related]

  • 16. Differential regulation of ceramide in lipid-rich microdomains (rafts): antagonistic role of palmitoyl:protein thioesterase and neutral sphingomyelinase 2.
    Goswami R, Ahmed M, Kilkus J, Han T, Dawson SA, Dawson G.
    J Neurosci Res; 2005 Jul 15; 81(2):208-17. PubMed ID: 15929065
    [Abstract] [Full Text] [Related]

  • 17. Ceramides and sphingomyelinases in senile plaques.
    Panchal M, Gaudin M, Lazar AN, Salvati E, Rivals I, Ayciriex S, Dauphinot L, Dargère D, Auzeil N, Masserini M, Laprévote O, Duyckaerts C.
    Neurobiol Dis; 2014 May 15; 65():193-201. PubMed ID: 24486621
    [Abstract] [Full Text] [Related]

  • 18. Role of sphingomyelinase in mitochondrial ceramide accumulation during reperfusion.
    Ramírez-Camacho I, Bautista-Pérez R, Correa F, Buelna-Chontal M, Román-Anguiano NG, Medel-Franco M, Medina-Campos ON, Pedraza-Chaverri J, Cano-Martínez A, Zazueta C.
    Biochim Biophys Acta; 2016 Oct 15; 1862(10):1955-63. PubMed ID: 27479697
    [Abstract] [Full Text] [Related]

  • 19. Sphingomyelinase dependent apoptosis following treatment of pancreatic beta-cells with amyloid peptides Abeta(1-42) or IAPP.
    Zhang Y, Ranta F, Tang C, Shumilina E, Mahmud H, Föller M, Ullrich S, Häring HU, Lang F.
    Apoptosis; 2009 Jul 15; 14(7):878-89. PubMed ID: 19488858
    [Abstract] [Full Text] [Related]

  • 20. Synovial fibroblasts and the sphingomyelinase pathway: sphingomyelin turnover and ceramide generation are not signaling mechanisms for the actions of tumor necrosis factor-alpha.
    Gerritsen ME, Shen CP, Perry CA.
    Am J Pathol; 1998 Feb 15; 152(2):505-12. PubMed ID: 9466577
    [Abstract] [Full Text] [Related]

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