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Journal Abstract Search

524 related items for PubMed ID: 14709618

  • 1. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
    Song X, Xie M, Zhang H, Li Y, Sachdeva K, Yan B.
    Drug Metab Dispos; 2004 Jan; 32(1):35-42. PubMed ID: 14709618
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  • 2. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L, Svecova L, Anzenbacherova E, Vrzal R, Staud F, Dvorak Z, Ulrichova J, Anzenbacher P, Pavek P.
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
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  • 3. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
    Faucette SR, Sueyoshi T, Smith CM, Negishi M, Lecluyse EL, Wang H.
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
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  • 9. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
    Chang HY, Chen CJ, Ma WC, Cheng WK, Lin YN, Lee YR, Chen JJ, Lim YP.
    Phytomedicine; 2017 Dec 01; 36():37-49. PubMed ID: 29157826
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  • 10. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
    Hoffart E, Ghebreghiorghis L, Nussler AK, Thasler WE, Weiss TS, Schwab M, Burk O.
    Br J Pharmacol; 2012 Mar 01; 165(5):1595-608. PubMed ID: 21913896
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  • 11. The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4alpha.
    Liu FJ, Song X, Yang D, Deng R, Yan B.
    Biochem J; 2008 Jan 01; 409(1):243-50. PubMed ID: 17764444
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  • 14. A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.
    Lemaire G, de Sousa G, Rahmani R.
    Biochem Pharmacol; 2004 Dec 15; 68(12):2347-58. PubMed ID: 15548381
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  • 17. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
    Sahi J, Shord SS, Lindley C, Ferguson S, LeCluyse EL.
    J Biochem Mol Toxicol; 2009 Dec 15; 23(1):43-58. PubMed ID: 19202563
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  • 19. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.
    Li L, Stanton JD, Tolson AH, Luo Y, Wang H.
    Pharm Res; 2009 Apr 15; 26(4):872-82. PubMed ID: 19034627
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