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Journal Abstract Search

524 related items for PubMed ID: 14709618

  • 1. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
    Song X, Xie M, Zhang H, Li Y, Sachdeva K, Yan B.
    Drug Metab Dispos; 2004 Jan; 32(1):35-42. PubMed ID: 14709618
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  • 3. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
    Faucette SR, Sueyoshi T, Smith CM, Negishi M, Lecluyse EL, Wang H.
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
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  • 4. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
    Casabar RC, Das PC, Dekrey GK, Gardiner CS, Cao Y, Rose RL, Wallace AD.
    Toxicol Appl Pharmacol; 2010 Jun 15; 245(3):335-43. PubMed ID: 20361990
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  • 5. Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
    Wang H, Faucette SR, Gilbert D, Jolley SL, Sueyoshi T, Negishi M, LeCluyse EL.
    Drug Metab Dispos; 2003 May 15; 31(5):620-30. PubMed ID: 12695351
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  • 6. The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
    Sugatani J, Yamakawa K, Tonda E, Nishitani S, Yoshinari K, Degawa M, Abe I, Noguchi H, Miwa M.
    Biochem Pharmacol; 2004 Mar 01; 67(5):989-1000. PubMed ID: 15104253
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  • 7. Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region.
    Koyano S, Kurose K, Saito Y, Ozawa S, Hasegawa R, Komamura K, Ueno K, Kamakura S, Kitakaze M, Nakajima T, Matsumoto K, Akasawa A, Saito H, Sawada J.
    Drug Metab Dispos; 2004 Jan 01; 32(1):149-54. PubMed ID: 14709632
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  • 9. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
    Chang HY, Chen CJ, Ma WC, Cheng WK, Lin YN, Lee YR, Chen JJ, Lim YP.
    Phytomedicine; 2017 Dec 01; 36():37-49. PubMed ID: 29157826
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  • 10. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
    Hoffart E, Ghebreghiorghis L, Nussler AK, Thasler WE, Weiss TS, Schwab M, Burk O.
    Br J Pharmacol; 2012 Mar 01; 165(5):1595-608. PubMed ID: 21913896
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  • 15. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
    Wang H, Faucette S, Sueyoshi T, Moore R, Ferguson S, Negishi M, LeCluyse EL.
    J Biol Chem; 2003 Apr 18; 278(16):14146-52. PubMed ID: 12571232
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  • 17. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
    Sahi J, Shord SS, Lindley C, Ferguson S, LeCluyse EL.
    J Biochem Mol Toxicol; 2009 Apr 18; 23(1):43-58. PubMed ID: 19202563
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  • 19. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.
    Li L, Stanton JD, Tolson AH, Luo Y, Wang H.
    Pharm Res; 2009 Apr 18; 26(4):872-82. PubMed ID: 19034627
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