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Journal Abstract Search

202 related items for PubMed ID: 14711931

  • 1. Application of a kinetic model to the apparently complex behavior of negative and positive allosteric modulators of muscarinic acetylcholine receptors.
    Avlani V, May LT, Sexton PM, Christopoulos A.
    J Pharmacol Exp Ther; 2004 Mar; 308(3):1062-72. PubMed ID: 14711931
    [Abstract] [Full Text] [Related]

  • 2. The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions.
    Avlani VA, McLoughlin DJ, Sexton PM, Christopoulos A.
    J Pharmacol Exp Ther; 2008 Jun; 325(3):927-34. PubMed ID: 18322151
    [Abstract] [Full Text] [Related]

  • 3. Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptors.
    Tränkle C, Weyand O, Voigtländer U, Mynett A, Lazareno S, Birdsall NJ, Mohr K.
    Mol Pharmacol; 2003 Jul; 64(1):180-90. PubMed ID: 12815174
    [Abstract] [Full Text] [Related]

  • 4. Changes of cooperativity between N-methylscopolamine and allosteric modulators alcuronium and gallamine induced by mutations of external loops of muscarinic M(3) receptors.
    Krejcí A, Tucek S.
    Mol Pharmacol; 2001 Oct; 60(4):761-7. PubMed ID: 11562438
    [Abstract] [Full Text] [Related]

  • 5. Regulation of M2 muscarinic acetylcholine receptor expression and signaling by prolonged exposure to allosteric modulators.
    May LT, Lin Y, Sexton PM, Christopoulos A.
    J Pharmacol Exp Ther; 2005 Jan; 312(1):382-90. PubMed ID: 15333678
    [Abstract] [Full Text] [Related]

  • 6. Interaction studies of multiple binding sites on m4 muscarinic acetylcholine receptors.
    Lanzafame AA, Sexton PM, Christopoulos A.
    Mol Pharmacol; 2006 Aug; 70(2):736-46. PubMed ID: 16709648
    [Abstract] [Full Text] [Related]

  • 7. Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors.
    May LT, Avlani VA, Langmead CJ, Herdon HJ, Wood MD, Sexton PM, Christopoulos A.
    Mol Pharmacol; 2007 Aug; 72(2):463-76. PubMed ID: 17525129
    [Abstract] [Full Text] [Related]

  • 8. Three allosteric modulators act at a common site, distinct from that of competitive antagonists, at muscarinic acetylcholine M2 receptors.
    Lanzafame A, Christopoulos A, Mitchelson F.
    J Pharmacol Exp Ther; 1997 Jul; 282(1):278-85. PubMed ID: 9223565
    [Abstract] [Full Text] [Related]

  • 9. Investigation of the interaction of a putative allosteric modulator, N-(2,3-diphenyl-1,2,4-thiadiazole-5-(2H)-ylidene) methanamine hydrobromide (SCH-202676), with M1 muscarinic acetylcholine receptors.
    Lanzafame A, Christopoulos A.
    J Pharmacol Exp Ther; 2004 Mar; 308(3):830-7. PubMed ID: 14617684
    [Abstract] [Full Text] [Related]

  • 10. New insight into active muscarinic receptors with the novel radioagonist [³H]iperoxo.
    Schrage R, Holze J, Klöckner J, Balkow A, Klause AS, Schmitz AL, De Amici M, Kostenis E, Tränkle C, Holzgrabe U, Mohr K.
    Biochem Pharmacol; 2014 Aug 01; 90(3):307-19. PubMed ID: 24863257
    [Abstract] [Full Text] [Related]

  • 11. A novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the M2 muscarinic receptor.
    Steinfeld T, Mammen M, Smith JA, Wilson RD, Jasper JR.
    Mol Pharmacol; 2007 Aug 01; 72(2):291-302. PubMed ID: 17478612
    [Abstract] [Full Text] [Related]

  • 12. Testing the specificity of allosteric modulators of muscarinic receptors in phylogenetically closely related histamine H1-receptors.
    Franken C, Tränkle C, Mohr K.
    Naunyn Schmiedebergs Arch Pharmacol; 2000 Feb 01; 361(2):107-12. PubMed ID: 10685864
    [Abstract] [Full Text] [Related]

  • 13. Competition between positive and negative allosteric effectors on muscarinic receptors.
    Proska J, Tucek S.
    Mol Pharmacol; 1995 Oct 01; 48(4):696-702. PubMed ID: 7476896
    [Abstract] [Full Text] [Related]

  • 14. Development of a radioligand, [(3)H]LY2119620, to probe the human M(2) and M(4) muscarinic receptor allosteric binding sites.
    Schober DA, Croy CH, Xiao H, Christopoulos A, Felder CC.
    Mol Pharmacol; 2014 Jul 01; 86(1):116-23. PubMed ID: 24807966
    [Abstract] [Full Text] [Related]

  • 15. Two-state models and the analysis of the allosteric effect of gallamine at the M2 muscarinic receptor.
    Ehlert FJ, Griffin MT.
    J Pharmacol Exp Ther; 2008 Jun 01; 325(3):1039-60. PubMed ID: 18305010
    [Abstract] [Full Text] [Related]

  • 16. Modes of allosteric interactions with free and [3H]N-methylscopolamine-occupied muscarinic M2 receptors as deduced from buffer-dependent potency shifts.
    Schröter A, Tränkle C, Mohr K.
    Naunyn Schmiedebergs Arch Pharmacol; 2000 Dec 01; 362(6):512-9. PubMed ID: 11138843
    [Abstract] [Full Text] [Related]

  • 17. Allosteric binding sites on muscarinic acetylcholine receptors.
    Wess J.
    Mol Pharmacol; 2005 Dec 01; 68(6):1506-9. PubMed ID: 16183853
    [Abstract] [Full Text] [Related]

  • 18. Allosteric interaction of the neuromuscular blockers vecuronium and pancuronium with recombinant human muscarinic M2 receptors.
    Cembala TM, Forde SC, Appadu BL, Lambert DG.
    Eur J Pharmacol; 2007 Aug 13; 569(1-2):37-40. PubMed ID: 17588565
    [Abstract] [Full Text] [Related]

  • 19. Using a radioalloster to test predictions of the cooperativity model for gallamine binding to the allosteric site of muscarinic acetylcholine M(2) receptors.
    Tränkle C, Weyand O, Schröter A, Mohr K.
    Mol Pharmacol; 1999 Nov 13; 56(5):962-5. PubMed ID: 10531401
    [Abstract] [Full Text] [Related]

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