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384 related items for PubMed ID: 14722330

  • 1. SSR126768A (4-chloro-3-[(3R)-(+)-5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-ethyl-N-(3-pyridylmethyl)-benzamide, hydrochloride): a new selective and orally active oxytocin receptor antagonist for the prevention of preterm labor.
    Serradeil-Le Gal C, Valette G, Foulon L, Germain G, Advenier C, Naline E, Bardou M, Martinolle JP, Pouzet B, Raufaste D, Garcia C, Double-Cazanave E, Pauly M, Pascal M, Barbier A, Scatton B, Maffrand JP, Le Fur G.
    J Pharmacol Exp Ther; 2004 Apr; 309(1):414-24. PubMed ID: 14722330
    [Abstract] [Full Text] [Related]

  • 2. Pharmacology of (2S,4Z)-N-[(2S)-2-hydroxy-2-phenylethyl]-4-(methoxyimino) -1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide, a new potent and selective nonpeptide antagonist of the oxytocin receptor.
    Cirillo R, Gillio Tos E, Schwarz MK, Quattropani A, Scheer A, Missotten M, Dorbais J, Nichols A, Borrelli F, Giachetti C, Golzio L, Marinelli P, Thomas RJ, Chevillard C, Laurent F, Portet K, Barberis C, Chollet A.
    J Pharmacol Exp Ther; 2003 Jul; 306(1):253-61. PubMed ID: 12660315
    [Abstract] [Full Text] [Related]

  • 3. Design of peptide oxytocin antagonists with strikingly higher affinities and selectivities for the human oxytocin receptor than atosiban.
    Manning M, Cheng LL, Stoev S, Wo NC, Chan WY, Szeto HH, Durroux T, Mouillac B, Barberis C.
    J Pept Sci; 2005 Oct; 11(10):593-608. PubMed ID: 15880385
    [Abstract] [Full Text] [Related]

  • 4. Barusiban suppresses oxytocin-induced preterm labour in non-human primates.
    Reinheimer TM.
    BMC Pregnancy Childbirth; 2007 Jun 01; 7 Suppl 1(Suppl 1):S15. PubMed ID: 17570159
    [Abstract] [Full Text] [Related]

  • 5. Arrest of preterm labor in rat and mouse by an oral and selective nonprostanoid antagonist of the prostaglandin F2alpha receptor (FP).
    Cirillo R, Tos EG, Page P, Missotten M, Quattropani A, Scheer A, Schwarz MK, Chollet A.
    Am J Obstet Gynecol; 2007 Jul 01; 197(1):54.e1-9. PubMed ID: 17618756
    [Abstract] [Full Text] [Related]

  • 6. Isosteric substitution of Asn5 in antagonists of oxytocin and vasopressin leads to highly selective and potent oxytocin and V1a receptor antagonists: new approaches for the design of potential tocolytics for preterm labor.
    Chan WY, Wo NC, Cheng LL, Manning M.
    J Pharmacol Exp Ther; 1996 May 01; 277(2):999-1003. PubMed ID: 8627583
    [Abstract] [Full Text] [Related]

  • 7. Tocolytic effect of a selective FP receptor antagonist in rodent models reveals an innovative approach to the treatment of preterm labor.
    Chollet A, Tos EG, Cirillo R.
    BMC Pregnancy Childbirth; 2007 Jun 01; 7 Suppl 1(Suppl 1):S16. PubMed ID: 17570160
    [Abstract] [Full Text] [Related]

  • 8. SSR240612 [(2R)-2-[((3R)-3-(1,3-benzodioxol-5-yl)-3-[[(6-methoxy-2-naphthyl)sulfonyl]amino]propanoyl)amino]-3-(4-[[2R,6S)-2,6-dimethylpiperidinyl]methyl]phenyl)-N-isopropyl-N-methylpropanamide hydrochloride], a new nonpeptide antagonist of the bradykinin B1 receptor: biochemical and pharmacological characterization.
    Gougat J, Ferrari B, Sarran L, Planchenault C, Poncelet M, Maruani J, Alonso R, Cudennec A, Croci T, Guagnini F, Urban-Szabo K, Martinolle JP, Soubrié P, Finance O, Le Fur G.
    J Pharmacol Exp Ther; 2004 May 01; 309(2):661-9. PubMed ID: 14747609
    [Abstract] [Full Text] [Related]

  • 9. Identification of an orally active, nonpeptidyl oxytocin antagonist.
    Pettibone DJ, Clineschmidt BV, Kishel MT, Lis EV, Reiss DR, Woyden CJ, Evans BE, Freidinger RM, Veber DF, Cook MJ.
    J Pharmacol Exp Ther; 1993 Jan 01; 264(1):308-14. PubMed ID: 8423533
    [Abstract] [Full Text] [Related]

  • 10. In vitro and in vivo pharmacological characterization of ethyl-4-[trans-4-[((2S)-2-hydroxy-3-[4-hydroxy-3[(methylsulfonyl)amino]-phenoxy]propyl) amino]cyclohexyl]benzoate hydrochloride (SAR150640), a new potent and selective human beta3-adrenoceptor agonist for the treatment of preterm labor.
    Croci T, Cecchi R, Marini P, Rouget C, Viviani N, Germain G, Guagnini F, Fradin Y, Descamps L, Pascal M, Advenier C, Breuiller-Fouché M, Leroy MJ, Bardou M.
    J Pharmacol Exp Ther; 2007 Jun 01; 321(3):1118-26. PubMed ID: 17351104
    [Abstract] [Full Text] [Related]

  • 11. Profile of an oxytocin antagonist, RWJ 22164 for treatment of preterm labor in laboratory models of uterine contractility.
    Demarest KT, Hahn DW, Ericson E, Capetola RJ, Fuchs AR, McGuire JL.
    Am J Perinatol; 1989 Apr 01; 6(2):200-4. PubMed ID: 2712917
    [Abstract] [Full Text] [Related]

  • 12. Oxytocin receptor blockade: a new principle in the treatment of preterm labor?
    Andersen LF, Lyndrup J, Akerlund M, Melin P.
    Am J Perinatol; 1989 Apr 01; 6(2):196-9. PubMed ID: 2540760
    [Abstract] [Full Text] [Related]

  • 13. Oxytocin antagonist (dTVT) and oxytocin receptors in myometrium and decidua.
    Fuchs AR, Vangsted A, Ivanisevic M, Demarest K.
    Am J Perinatol; 1989 Apr 01; 6(2):205-8. PubMed ID: 2540761
    [Abstract] [Full Text] [Related]

  • 14. Discovery and development of a new class of potent, selective, orally active oxytocin receptor antagonists.
    Quattropani A, Dorbais J, Covini D, Pittet PA, Colovray V, Thomas RJ, Coxhead R, Halazy S, Scheer A, Missotten M, Ayala G, Bradshaw C, De Raemy-Schenk AM, Nichols A, Cirillo R, Tos EG, Giachetti C, Golzio L, Marinelli P, Church DJ, Barberis C, Chollet A, Schwarz MK.
    J Med Chem; 2005 Dec 01; 48(24):7882-905. PubMed ID: 16302826
    [Abstract] [Full Text] [Related]

  • 15. Cigarette smoke extract enhances oxytocin-induced rhythmic contractions of rat and human preterm myometrium.
    Nakamoto T, Yasuda K, Yasuhara M, Nakajima T, Mizokami T, Okada H, Kanzaki H.
    Reproduction; 2006 Aug 01; 132(2):343-53. PubMed ID: 16885542
    [Abstract] [Full Text] [Related]

  • 16. Effects of YM471, a nonpeptide AVP V(1A) and V(2) receptor antagonist, on human AVP receptor subtypes expressed in CHO cells and oxytocin receptors in human uterine smooth muscle cells.
    Tsukada J, Tahara A, Tomura Y, Wada Ki, Kusayama T, Ishii N, Yatsu T, Uchida W, Taniguchi N, Tanaka A.
    Br J Pharmacol; 2001 Jul 01; 133(5):746-54. PubMed ID: 11429400
    [Abstract] [Full Text] [Related]

  • 17. Oxytocin receptor subtypes in the pregnant rat myometrium and decidua: pharmacological differentiations.
    Chan WY, Chen DL, Manning M.
    Endocrinology; 1993 Mar 01; 132(3):1381-6. PubMed ID: 8382600
    [Abstract] [Full Text] [Related]

  • 18. Novel in vitro system for functional assessment of oxytocin action.
    Devost D, Zingg HH.
    Am J Physiol Endocrinol Metab; 2007 Jan 01; 292(1):E1-6. PubMed ID: 16954329
    [Abstract] [Full Text] [Related]

  • 19. Progress in the development of oxytocin antagonists for use in preterm labor.
    Pettibone DJ, Guidotti M, Harrell CM, Jasper JR, Lis EV, O'Brien JA, Reiss DR, Woyden CJ, Bock MG, Evans BE.
    Adv Exp Med Biol; 1995 Jan 01; 395():601-12. PubMed ID: 8714024
    [Abstract] [Full Text] [Related]

  • 20. [The importance of oxytocin and prostaglandins to the mechanism of labor in humans].
    Husslein P.
    Wien Klin Wochenschr Suppl; 1984 Jan 01; 155():1-32. PubMed ID: 6099005
    [Abstract] [Full Text] [Related]


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