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2. Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb. Sagai T, Hosoya M, Mizushina Y, Tamura M, Shiroishi T. Development; 2005 Feb; 132(4):797-803. PubMed ID: 15677727 [Abstract] [Full Text] [Related]
3. A series of ENU-induced single-base substitutions in a long-range cis-element altering Sonic hedgehog expression in the developing mouse limb bud. Masuya H, Sezutsu H, Sakuraba Y, Sagai T, Hosoya M, Kaneda H, Miura I, Kobayashi K, Sumiyama K, Shimizu A, Nagano J, Yokoyama H, Kaneko S, Sakurai N, Okagaki Y, Noda T, Wakana S, Gondo Y, Shiroishi T. Genomics; 2007 Feb; 89(2):207-14. PubMed ID: 17049204 [Abstract] [Full Text] [Related]
5. Progression of vertebrate limb development through SHH-mediated counteraction of GLI3. te Welscher P, Zuniga A, Kuijper S, Drenth T, Goedemans HJ, Meijlink F, Zeller R. Science; 2002 Oct 25; 298(5594):827-30. PubMed ID: 12215652 [Abstract] [Full Text] [Related]
6. Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function. Chiang C, Litingtung Y, Harris MP, Simandl BK, Li Y, Beachy PA, Fallon JF. Dev Biol; 2001 Aug 15; 236(2):421-35. PubMed ID: 11476582 [Abstract] [Full Text] [Related]
7. The mouse polydactylous mutation, luxate (lx), causes anterior shift of the anteroposterior border in the developing hindlimb bud. Yada Y, Makino S, Chigusa-Ishiwa S, Shiroishi T. Int J Dev Biol; 2002 Aug 15; 46(7):975-82. PubMed ID: 12455637 [Abstract] [Full Text] [Related]
8. Multigenic control of the localization of the zone of polarizing activity in limb morphogenesis in the mouse. Masuya H, Sagai T, Moriwaki K, Shiroishi T. Dev Biol; 1997 Feb 01; 182(1):42-51. PubMed ID: 9073443 [Abstract] [Full Text] [Related]
10. Sonic hedgehog: restricted expression and limb dysmorphologies. Hill RE, Heaney SJ, Lettice LA. J Anat; 2003 Jan 01; 202(1):13-20. PubMed ID: 12587915 [Abstract] [Full Text] [Related]
11. Expression profile of Gli family members and Shh in normal and mutant mouse limb development. Büscher D, Rüther U. Dev Dyn; 1998 Jan 01; 211(1):88-96. PubMed ID: 9438426 [Abstract] [Full Text] [Related]
12. A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly. Lettice LA, Heaney SJ, Purdie LA, Li L, de Beer P, Oostra BA, Goode D, Elgar G, Hill RE, de Graaff E. Hum Mol Genet; 2003 Jul 15; 12(14):1725-35. PubMed ID: 12837695 [Abstract] [Full Text] [Related]
13. Two Types of Etiological Mutation in the Limb-Specific Enhancer of Shh. Amano T, Sagai T, Seki R, Shiroishi T. G3 (Bethesda); 2017 Sep 07; 7(9):2991-2998. PubMed ID: 28710291 [Abstract] [Full Text] [Related]
14. Sonic hedgehog signaling during digit pattern duplication after application of recombinant protein and expressing cells. Wada N, Kawakami Y, Nohno T. Dev Growth Differ; 1999 Oct 07; 41(5):567-74. PubMed ID: 10545029 [Abstract] [Full Text] [Related]
15. Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud. Krebs O, Schreiner CM, Scott WJ, Bell SM, Robbins DJ, Goetz JA, Alt H, Hawes N, Wolf E, Favor J. Development; 2003 Dec 07; 130(24):6037-47. PubMed ID: 14597572 [Abstract] [Full Text] [Related]
16. Single base pair change in the long-range Sonic hedgehog limb-specific enhancer is a genetic basis for preaxial polydactyly. Maas SA, Fallon JF. Dev Dyn; 2005 Feb 07; 232(2):345-8. PubMed ID: 15637698 [Abstract] [Full Text] [Related]
17. Developmental mechanisms underlying polydactyly in the mouse mutant Doublefoot. Crick AP, Babbs C, Brown JM, Morriss-Kay GM. J Anat; 2003 Jan 07; 202(1):21-6. PubMed ID: 12587916 [Abstract] [Full Text] [Related]
18. A novel candidate gene for mouse and human preaxial polydactyly with altered expression in limbs of Hemimelic extra-toes mutant mice. Clark RM, Marker PC, Kingsley DM. Genomics; 2000 Jul 01; 67(1):19-27. PubMed ID: 10945466 [Abstract] [Full Text] [Related]
19. Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice. Akiyama H, Stadler HS, Martin JF, Ishii TM, Beachy PA, Nakamura T, de Crombrugghe B. Matrix Biol; 2007 May 01; 26(4):224-33. PubMed ID: 17222543 [Abstract] [Full Text] [Related]