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269 related items for PubMed ID: 14729457

  • 1. Inhibition of p38 mitogen-activated protein kinase reduces TNF-induced activation of NF-kappaB, elicits caspase activity, and enhances cytotoxicity.
    Lüschen S, Scherer G, Ussat S, Ungefroren H, Adam-Klages S.
    Exp Cell Res; 2004 Feb 15; 293(2):196-206. PubMed ID: 14729457
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of p38 kinase reveals a TNF-alpha-mediated, caspase-dependent, apoptotic death pathway in a human myelomonocyte cell line.
    Varghese J, Chattopadhaya S, Sarin A.
    J Immunol; 2001 Jun 01; 166(11):6570-7. PubMed ID: 11359809
    [Abstract] [Full Text] [Related]

  • 3. Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.
    Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB.
    Oncogene; 2007 Feb 22; 26(8):1201-12. PubMed ID: 16924232
    [Abstract] [Full Text] [Related]

  • 4. Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis.
    Saeki K, Kobayashi N, Inazawa Y, Zhang H, Nishitoh H, Ichijo H, Saeki K, Isemura M, Yuo A.
    Biochem J; 2002 Dec 15; 368(Pt 3):705-20. PubMed ID: 12206715
    [Abstract] [Full Text] [Related]

  • 5. Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells.
    Takada Y, Sethi G, Sung B, Aggarwal BB.
    Mol Pharmacol; 2008 May 15; 73(5):1549-57. PubMed ID: 18287248
    [Abstract] [Full Text] [Related]

  • 6. Intracellular signaling in rat cultured vascular smooth muscle cells: roles of nuclear factor-kappaB and p38 mitogen-activated protein kinase on tumor necrosis factor-alpha production.
    Yamakawa T, Eguchi S, Matsumoto T, Yamakawa Y, Numaguchi K, Miyata I, Reynolds CM, Motley ED, Inagami T.
    Endocrinology; 1999 Aug 15; 140(8):3562-72. PubMed ID: 10433212
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity.
    Zhang L, Himi T, Morita I, Murota S.
    Cell Death Differ; 2001 May 15; 8(5):528-36. PubMed ID: 11423913
    [Abstract] [Full Text] [Related]

  • 8. Tumour necrosis factor-induced activation of c-Jun N-terminal kinase is sensitive to caspase-dependent modulation while activation of mitogen-activated protein kinase (MAPK) or p38 MAPK is not.
    Mohamed AA, Jupp OJ, Anderson HM, Littlejohn AF, Vandenabeele P, MacEwan DJ.
    Biochem J; 2002 Aug 15; 366(Pt 1):145-55. PubMed ID: 11996667
    [Abstract] [Full Text] [Related]

  • 9. p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system.
    Craig R, Larkin A, Mingo AM, Thuerauf DJ, Andrews C, McDonough PM, Glembotski CC.
    J Biol Chem; 2000 Aug 04; 275(31):23814-24. PubMed ID: 10781614
    [Abstract] [Full Text] [Related]

  • 10. Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils.
    Nick JA, Avdi NJ, Young SK, Lehman LA, McDonald PP, Frasch SC, Billstrom MA, Henson PM, Johnson GL, Worthen GS.
    J Clin Invest; 1999 Mar 04; 103(6):851-8. PubMed ID: 10079106
    [Abstract] [Full Text] [Related]

  • 11. MKK6/3 and p38 MAPK pathway activation is not necessary for insulin-induced glucose uptake but regulates glucose transporter expression.
    Fujishiro M, Gotoh Y, Katagiri H, Sakoda H, Ogihara T, Anai M, Onishi Y, Ono H, Funaki M, Inukai K, Fukushima Y, Kikuchi M, Oka Y, Asano T.
    J Biol Chem; 2001 Jun 08; 276(23):19800-6. PubMed ID: 11279172
    [Abstract] [Full Text] [Related]

  • 12. Sensitization of apoptotically-resistant breast carcinoma cells to TNF and TRAIL by inhibition of p38 mitogen-activated protein kinase signaling.
    Weldon CB, Parker AP, Patten D, Elliott S, Tang Y, Frigo DE, Dugan CM, Coakley EL, Butler NN, Clayton JL, Alam J, Curiel TJ, Beckman BS, Jaffe BM, Burow ME.
    Int J Oncol; 2004 Jun 08; 24(6):1473-80. PubMed ID: 15138590
    [Abstract] [Full Text] [Related]

  • 13. Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.
    Madrid LV, Mayo MW, Reuther JY, Baldwin AS.
    J Biol Chem; 2001 Jun 01; 276(22):18934-40. PubMed ID: 11259436
    [Abstract] [Full Text] [Related]

  • 14. p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L).
    Grethe S, Ares MP, Andersson T, Pörn-Ares MI.
    Exp Cell Res; 2004 Aug 15; 298(2):632-42. PubMed ID: 15265709
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of nuclear factor kappaB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor alpha in mice.
    Imose M, Nagaki M, Naiki T, Osawa Y, Brenner DA, Asano T, Hayashi H, Kato T, Moriwaki H.
    Liver Int; 2003 Oct 15; 23(5):386-96. PubMed ID: 14708901
    [Abstract] [Full Text] [Related]

  • 16. The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor.
    Beyaert R, Cuenda A, Vanden Berghe W, Plaisance S, Lee JC, Haegeman G, Cohen P, Fiers W.
    EMBO J; 1996 Apr 15; 15(8):1914-23. PubMed ID: 8617238
    [Abstract] [Full Text] [Related]

  • 17. Activation of p38 mitogen-activated protein kinase and nuclear factor-kappaB in tumour necrosis factor-induced eotaxin release of human eosinophils.
    Wong CK, Zhang JP, Ip WK, Lam CW.
    Clin Exp Immunol; 2002 Jun 15; 128(3):483-9. PubMed ID: 12067303
    [Abstract] [Full Text] [Related]

  • 18. Tumor necrosis factor-alpha induction of endothelial ephrin A1 expression is mediated by a p38 MAPK- and SAPK/JNK-dependent but nuclear factor-kappa B-independent mechanism.
    Cheng N, Chen J.
    J Biol Chem; 2001 Apr 27; 276(17):13771-7. PubMed ID: 11278471
    [Abstract] [Full Text] [Related]

  • 19. The p38 MAP kinase inhibitor SB203580 enhances nuclear factor-kappa B transcriptional activity by a non-specific effect upon the ERK pathway.
    Birkenkamp KU, Tuyt LM, Lummen C, Wierenga AT, Kruijer W, Vellenga E.
    Br J Pharmacol; 2000 Sep 27; 131(1):99-107. PubMed ID: 10960075
    [Abstract] [Full Text] [Related]

  • 20. Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression via sequential activation of ceramide-dependent mitogen-activated protein kinases, and IkappaB kinase 1/2 in human alveolar epithelial cells.
    Chen CC, Sun YT, Chen JJ, Chang YJ.
    Mol Pharmacol; 2001 Mar 27; 59(3):493-500. PubMed ID: 11179444
    [Abstract] [Full Text] [Related]

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