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185 related items for PubMed ID: 14746469

  • 1. Discovery of potent cell migration inhibitors through total synthesis: lessons from structure-activity studies of (+)-migrastatin.
    Njardarson JT, Gaul C, Shan D, Huang XY, Danishefsky SJ.
    J Am Chem Soc; 2004 Feb 04; 126(4):1038-40. PubMed ID: 14746469
    [Abstract] [Full Text] [Related]

  • 2. The migrastatin family: discovery of potent cell migration inhibitors by chemical synthesis.
    Gaul C, Njardarson JT, Shan D, Dorn DC, Wu KD, Tong WP, Huang XY, Moore MA, Danishefsky SJ.
    J Am Chem Soc; 2004 Sep 15; 126(36):11326-37. PubMed ID: 15355116
    [Abstract] [Full Text] [Related]

  • 3. Synthesis of novel migrastatin and dorrigocin A analogues from D-glucal.
    Anquetin G, Rawe SL, McMahon K, Murphy EP, Murphy PV.
    Chemistry; 2008 Sep 15; 14(5):1592-600. PubMed ID: 18038383
    [Abstract] [Full Text] [Related]

  • 4. The total synthesis of (+)-migrastatin.
    Gaul C, Njardarson JT, Danishefsky SJ.
    J Am Chem Soc; 2003 May 21; 125(20):6042-3. PubMed ID: 12785819
    [Abstract] [Full Text] [Related]

  • 5. Synthesis of Migrastatin Analogues as Inhibitors of Tumour Cell Migration: Exploring Structural Change in and on the Macrocyclic Ring.
    Lo Re D, Zhou Y, Mucha J, Jones LF, Leahy L, Santocanale C, Krol M, Murphy PV.
    Chemistry; 2015 Dec 07; 21(50):17993. PubMed ID: 26537992
    [Abstract] [Full Text] [Related]

  • 6. Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration.
    Ju J, Rajski SR, Lim SK, Seo JW, Peters NR, Hoffmann FM, Shen B.
    J Am Chem Soc; 2009 Feb 04; 131(4):1370-1. PubMed ID: 19132897
    [Abstract] [Full Text] [Related]

  • 7. Total synthesis of (+)-isomigrastatin.
    Krauss IJ, Mandal M, Danishefsky SJ.
    Angew Chem Int Ed Engl; 2007 Feb 04; 46(29):5576-9. PubMed ID: 17583888
    [No Abstract] [Full Text] [Related]

  • 8. Migrastatin acts as a muscarinic acetylcholine receptor antagonist.
    Nakae K, Nishimura Y, Ohba S, Akamatsu Y.
    J Antibiot (Tokyo); 2006 Nov 04; 59(11):685-92. PubMed ID: 17256466
    [Abstract] [Full Text] [Related]

  • 9. Suppression of multidrug resistance by migrastatin.
    Takemoto Y, Tashiro E, Imoto M.
    J Antibiot (Tokyo); 2006 Jul 04; 59(7):435-8. PubMed ID: 17025021
    [Abstract] [Full Text] [Related]

  • 10. Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1. Taxonomy, fermentation, isolation and biological activities.
    Nakae K, Yoshimoto Y, Sawa T, Homma Y, Hamada M, Takeuchi T, Imoto M.
    J Antibiot (Tokyo); 2000 Oct 04; 53(10):1130-6. PubMed ID: 11132958
    [Abstract] [Full Text] [Related]

  • 11. Synthesis of Migrastatin Analogues as Inhibitors of Tumour Cell Migration: Exploring Structural Change in and on the Macrocyclic Ring.
    Lo Re D, Zhou Y, Mucha J, Jones LF, Leahy L, Santocanale C, Krol M, Murphy PV.
    Chemistry; 2015 Dec 07; 21(50):18109-21. PubMed ID: 26531227
    [Abstract] [Full Text] [Related]

  • 12. Iso-migrastatin congeners from Streptomyces platensis and generation of a glutarimide polyketide library featuring the dorrigocin, lactimidomycin, migrastatin, and NK30424 scaffolds.
    Ju J, Lim SK, Jiang H, Seo JW, Shen B.
    J Am Chem Soc; 2005 Aug 31; 127(34):11930-1. PubMed ID: 16117518
    [Abstract] [Full Text] [Related]

  • 13. Thermolysis of isomigrastatin and its congeners via [3,3]-sigmatropic rearrangement: a new route to the synthesis of migrastatin and its analogues.
    Ju J, Lim SK, Jiang H, Seo JW, Her Y, Shen B.
    Org Lett; 2006 Dec 07; 8(25):5865-8. PubMed ID: 17134292
    [Abstract] [Full Text] [Related]

  • 14. Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency.
    Ju J, Rajski SR, Lim SK, Seo JW, Peters NR, Hoffmann FM, Shen B.
    Bioorg Med Chem Lett; 2008 Nov 15; 18(22):5951-4. PubMed ID: 18684620
    [Abstract] [Full Text] [Related]

  • 15. Concise total synthesis of the potent translation and cell migration inhibitor lactimidomycin.
    Micoine K, Fürstner A.
    J Am Chem Soc; 2010 Oct 13; 132(40):14064-6. PubMed ID: 20831202
    [Abstract] [Full Text] [Related]

  • 16. Migrastatin analogues inhibit canine mammary cancer cell migration and invasion.
    Majchrzak K, Lo Re D, Gajewska M, Bulkowska M, Homa A, Pawłowski K, Motyl T, Murphy PV, Król M.
    PLoS One; 2013 Oct 13; 8(10):e76789. PubMed ID: 24116159
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and cytotoxic properties of novel 1-[4-(2-alkylaminoethoxy)phenylcarbonyl]-3,5-bis(arylidene)-4-piperidones and related compounds.
    Das U, Alcorn J, Shrivastav A, Sharma RK, De Clercq E, Balzarini J, Dimmock JR.
    Eur J Med Chem; 2007 Jan 13; 42(1):71-80. PubMed ID: 16996657
    [Abstract] [Full Text] [Related]

  • 18. Discovery of novel taspine derivatives as antiangiogenic agents.
    Zhang J, Zhang Y, Zhang S, Wang S, He L.
    Bioorg Med Chem Lett; 2010 Jan 15; 20(2):718-21. PubMed ID: 20006929
    [Abstract] [Full Text] [Related]

  • 19. Migrastatin and dorrigocins are shunt metabolites of iso-migrastatin.
    Ju J, Lim SK, Jiang H, Shen B.
    J Am Chem Soc; 2005 Feb 16; 127(6):1622-3. PubMed ID: 15700980
    [Abstract] [Full Text] [Related]

  • 20. Synthesis of eukaryotic translation elongation inhibitor lactimidomycin via Zn(II)-mediated Horner-Wadsworth-Emmons macrocyclization.
    Larsen BJ, Sun Z, Nagorny P.
    Org Lett; 2013 Jun 21; 15(12):2998-3001. PubMed ID: 23731327
    [Abstract] [Full Text] [Related]

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