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339 related items for PubMed ID: 14767553

  • 1. FR901228, a novel histone deacetylase inhibitor, induces cell cycle arrest and subsequent apoptosis in refractory human pancreatic cancer cells.
    Sato N, Ohta T, Kitagawa H, Kayahara M, Ninomiya I, Fushida S, Fujimura T, Nishimura G, Shimizu K, Miwa K.
    Int J Oncol; 2004 Mar; 24(3):679-85. PubMed ID: 14767553
    [Abstract] [Full Text] [Related]

  • 2. Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity.
    Blagosklonny MV, Robey R, Sackett DL, Du L, Traganos F, Darzynkiewicz Z, Fojo T, Bates SE.
    Mol Cancer Ther; 2002 Sep; 1(11):937-41. PubMed ID: 12481415
    [Abstract] [Full Text] [Related]

  • 3. Antiproliferative effects of the histone deacetylase inhibitor FR901228 on small-cell lung cancer lines and drug-resistant sublines.
    Tsurutani J, Soda H, Oka M, Suenaga M, Doi S, Nakamura Y, Nakatomi K, Shiozawa K, Amada YY, Kamihira S, Kohno S.
    Int J Cancer; 2003 Mar 20; 104(2):238-42. PubMed ID: 12569581
    [Abstract] [Full Text] [Related]

  • 4. FR901228 induces tumor regression associated with induction of Fas ligand and activation of Fas signaling in human osteosarcoma cells.
    Imai T, Adachi S, Nishijo K, Ohgushi M, Okada M, Yasumi T, Watanabe K, Nishikomori R, Nakayama T, Yonehara S, Toguchida J, Nakahata T.
    Oncogene; 2003 Dec 18; 22(58):9231-42. PubMed ID: 14647441
    [Abstract] [Full Text] [Related]

  • 5. P21-dependent g(1)arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228.
    Sandor V, Senderowicz A, Mertins S, Sackett D, Sausville E, Blagosklonny MV, Bates SE.
    Br J Cancer; 2000 Sep 18; 83(6):817-25. PubMed ID: 10952788
    [Abstract] [Full Text] [Related]

  • 6. Pro-apoptotic activity of oncogenic H-Ras for histone deacetylase inhibitor to induce apoptosis of human cancer HT29 cells.
    Choudhary S, Wang HC.
    J Cancer Res Clin Oncol; 2007 Oct 18; 133(10):725-39. PubMed ID: 17487507
    [Abstract] [Full Text] [Related]

  • 7. Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell lines.
    Klisovic DD, Katz SE, Effron D, Klisovic MI, Wickham J, Parthun MR, Guimond M, Marcucci G.
    Invest Ophthalmol Vis Sci; 2003 Jun 18; 44(6):2390-8. PubMed ID: 12766035
    [Abstract] [Full Text] [Related]

  • 8. Romidepsin (depsipeptide) induced cell cycle arrest, apoptosis and histone hyperacetylation in lung carcinoma cells (A549) are associated with increase in p21 and hypophosphorylated retinoblastoma proteins expression.
    Vinodhkumar R, Song YS, Devaki T.
    Biomed Pharmacother; 2008 Feb 18; 62(2):85-93. PubMed ID: 17644301
    [Abstract] [Full Text] [Related]

  • 9. FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor.
    Nakajima H, Kim YB, Terano H, Yoshida M, Horinouchi S.
    Exp Cell Res; 1998 May 25; 241(1):126-33. PubMed ID: 9633520
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of histone deacetylases by chlamydocin induces apoptosis and proteasome-mediated degradation of survivin.
    De Schepper S, Bruwiere H, Verhulst T, Steller U, Andries L, Wouters W, Janicot M, Arts J, Van Heusden J.
    J Pharmacol Exp Ther; 2003 Feb 25; 304(2):881-8. PubMed ID: 12538846
    [Abstract] [Full Text] [Related]

  • 11. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
    Cheong JW, Chong SY, Kim JY, Eom JI, Jeung HK, Maeng HY, Lee ST, Min YH.
    Clin Cancer Res; 2003 Oct 15; 9(13):5018-27. PubMed ID: 14581377
    [Abstract] [Full Text] [Related]

  • 12. Apoptosis induced by the histone deacetylase inhibitor FR901228 in human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells.
    Mori N, Matsuda T, Tadano M, Kinjo T, Yamada Y, Tsukasaki K, Ikeda S, Yamasaki Y, Tanaka Y, Ohta T, Iwamasa T, Tomonaga M, Yamamoto N.
    J Virol; 2004 May 15; 78(9):4582-90. PubMed ID: 15078940
    [Abstract] [Full Text] [Related]

  • 13. CIL-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer PC-3 cell line.
    Huang YT, Huang DM, Guh JH, Chen IL, Tzeng CC, Teng CM.
    J Biol Chem; 2005 Jan 28; 280(4):2771-9. PubMed ID: 15536083
    [Abstract] [Full Text] [Related]

  • 14. Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells.
    Ahn MY, Lee J, Na YJ, Choi WS, Lee BM, Kang KW, Kim HS.
    Chem Biol Interact; 2009 May 15; 179(2-3):169-77. PubMed ID: 19070610
    [Abstract] [Full Text] [Related]

  • 15. SK-7041, a new histone deacetylase inhibitor, induces G2-M cell cycle arrest and apoptosis in pancreatic cancer cell lines.
    Ryu JK, Lee WJ, Lee KH, Hwang JH, Kim YT, Yoon YB, Kim CY.
    Cancer Lett; 2006 Jun 08; 237(1):143-54. PubMed ID: 16009488
    [Abstract] [Full Text] [Related]

  • 16. The histone deacetylase inhibitor FR901228 induces caspase-dependent apoptosis via the mitochondrial pathway in small cell lung cancer cells.
    Doi S, Soda H, Oka M, Tsurutani J, Kitazaki T, Nakamura Y, Fukuda M, Yamada Y, Kamihira S, Kohno S.
    Mol Cancer Ther; 2004 Nov 08; 3(11):1397-402. PubMed ID: 15542778
    [Abstract] [Full Text] [Related]

  • 17. Histone deacetylase inhibitor FR901228 enhances the antitumor effect of telomerase-specific replication-selective adenoviral agent OBP-301 in human lung cancer cells.
    Watanabe T, Hioki M, Fujiwara T, Nishizaki M, Kagawa S, Taki M, Kishimoto H, Endo Y, Urata Y, Tanaka N, Fujiwara T.
    Exp Cell Res; 2006 Feb 01; 312(3):256-65. PubMed ID: 16356494
    [Abstract] [Full Text] [Related]

  • 18. Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis.
    Park WH, Seol JG, Kim ES, Hyun JM, Jung CW, Lee CC, Kim BK, Lee YY.
    Cancer Res; 2000 Jun 01; 60(11):3065-71. PubMed ID: 10850458
    [Abstract] [Full Text] [Related]

  • 19. A natural histone deacetylase inhibitor, Psammaplin A, induces cell cycle arrest and apoptosis in human endometrial cancer cells.
    Ahn MY, Jung JH, Na YJ, Kim HS.
    Gynecol Oncol; 2008 Jan 01; 108(1):27-33. PubMed ID: 17920664
    [Abstract] [Full Text] [Related]

  • 20. Differential modulation of signaling pathways and apoptosis of ras-transformed 10T1/2 cells by the depsipeptide FR901228.
    Fecteau KA, Mei J, Wang HC.
    J Pharmacol Exp Ther; 2002 Mar 01; 300(3):890-9. PubMed ID: 11861795
    [Abstract] [Full Text] [Related]

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