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Journal Abstract Search

116 related items for PubMed ID: 1479589

  • 1. 5-HT3 receptor antagonists. 1. New quinoline derivatives.
    Hayashi H, Miwa Y, Miki I, Ichikawa S, Yoda N, Ishii A, Kono M, Suzuki F.
    J Med Chem; 1992 Dec 25; 35(26):4893-902. PubMed ID: 1479589
    [Abstract] [Full Text] [Related]

  • 2. 5-HT3 receptor antagonists. 2. 4-Hydroxy-3-quinolinecarboxylic acid derivatives.
    Hayashi H, Miwa Y, Ichikawa S, Yoda N, Miki I, Ishii A, Kono M, Yasuzawa T, Suzuki F.
    J Med Chem; 1993 Mar 05; 36(5):617-26. PubMed ID: 8496941
    [Abstract] [Full Text] [Related]

  • 3. 5-HT3 receptor antagonists. 3. Quinoline derivatives which may be effective in the therapy of irritable bowel syndrome.
    Kishibayashi N, Miwa Y, Hayashi H, Ishii A, Ichikawa S, Nonaka H, Yokoyama T, Suzuki F.
    J Med Chem; 1993 Oct 29; 36(22):3286-92. PubMed ID: 8230119
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and 5-HT3 receptor affinity of new quinolinecarboxylic acid derivatives.
    Orjales A, Alonso-Cires L, López-Tudanca PL, Tapia I, Labeaga L, Mosquera R.
    Drug Des Discov; 2000 Oct 29; 16(4):271-9. PubMed ID: 10807033
    [Abstract] [Full Text] [Related]

  • 5. Synthesis of a new class of 2,3-dihydro-2-oxo-1H-benzimidazole-1-carboxylic acid derivatives as highly potent 5-HT3 receptor antagonists.
    Turconi M, Nicola M, Quintero MG, Maiocchi L, Micheletti R, Giraldo E, Donetti A.
    J Med Chem; 1990 Aug 29; 33(8):2101-8. PubMed ID: 1695682
    [Abstract] [Full Text] [Related]

  • 6. Benzoxazines. II. Synthesis, conformational analysis, and structure--activity relationships of 3,4-dihydro-2H-1,4-benzoxazine-8-carboxamide derivatives as potent and long-acting serotonin-3 (5-HT3) receptor antagonists.
    Kuroita T, Marubayashi N, Sano M, Kanzaki K, Inaba K, Kawakita T.
    Chem Pharm Bull (Tokyo); 1996 Nov 29; 44(11):2051-60. PubMed ID: 8945770
    [Abstract] [Full Text] [Related]

  • 7. Phenylimidazolidin-2-one derivatives as selective 5-HT3 receptor antagonists and refinement of the pharmacophore model for 5-HT3 receptor binding.
    Heidempergher F, Pillan A, Pinciroli V, Vaghi F, Arrigoni C, Bolis G, Caccia C, Dho L, McArthur R, Varasi M.
    J Med Chem; 1997 Oct 10; 40(21):3369-80. PubMed ID: 9341912
    [Abstract] [Full Text] [Related]

  • 8. Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives.
    Cappelli A, Anzini M, Vomero S, Mennuni L, Makovec F, Doucet E, Hamon M, Bruni G, Romeo MR, Menziani MC, De Benedetti PG, Langer T.
    J Med Chem; 1998 Feb 26; 41(5):728-41. PubMed ID: 9513601
    [Abstract] [Full Text] [Related]

  • 9. Evaluation of the receptor selectivity of the H3 receptor antagonists, iodophenpropit and thioperamide: an interaction with the 5-HT3 receptor revealed.
    Leurs R, Tulp MT, Menge WM, Adolfs MJ, Zuiderveld OP, Timmerman H.
    Br J Pharmacol; 1995 Oct 26; 116(4):2315-21. PubMed ID: 8564266
    [Abstract] [Full Text] [Related]

  • 10. Benzimidazole derivatives. Part 1: Synthesis and structure-activity relationships of new benzimidazole-4-carboxamides and carboxylates as potent and selective 5-HT4 receptor antagonists.
    López-Rodríguez ML, Benhamú B, Viso A, Morcillo MJ, Murcia M, Orensanz L, Alfaro MJ, Martín MI.
    Bioorg Med Chem; 1999 Nov 26; 7(11):2271-81. PubMed ID: 10632037
    [Abstract] [Full Text] [Related]

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  • 12. New 2-piperazinylbenzimidazole derivatives as 5-HT3 antagonists. Synthesis and pharmacological evaluation.
    Orjales A, Mosquera R, Labeaga L, Rodes R.
    J Med Chem; 1997 Feb 14; 40(4):586-93. PubMed ID: 9046349
    [Abstract] [Full Text] [Related]

  • 13. Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors.
    Cappelli A, Anzini M, Vomero S, Canullo L, Mennuni L, Makovec F, Doucet E, Hamon M, Menziani MC, De Benedetti PG, Bruni G, Romeo MR, Giorgi G, Donati A.
    J Med Chem; 1999 May 06; 42(9):1556-75. PubMed ID: 10229626
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and structure-activity relationships of 2,3-dihydrobenzofuran-7-carboxamide derivatives as potent serotonin-3 (5-HT3) receptor antagonists.
    Kuroita T, Yasumoto M, Inaba K, Sakamori M, Takehara S, Kawakita T.
    Chem Pharm Bull (Tokyo); 1994 Jan 06; 42(1):95-100. PubMed ID: 8124772
    [Abstract] [Full Text] [Related]

  • 15. Characteristics of 5-HT3 binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [3H]-quipazine and [3H]-GR65630 binding.
    Sharif NA, Wong EH, Loury DN, Stefanich E, Michel AD, Eglen RM, Whiting RL.
    Br J Pharmacol; 1991 Apr 06; 102(4):919-25. PubMed ID: 1830236
    [Abstract] [Full Text] [Related]

  • 16. Design and synthesis of 6-chloro-3,4-dihydro-4-methyl-2H-1,4-benzoxazine-8-carboxamide derivatives as potent serotonin-3 (5-HT3) receptor antagonists.
    Kuroita T, Sakamori M, Kawakita T.
    Chem Pharm Bull (Tokyo); 1996 Apr 06; 44(4):756-64. PubMed ID: 8681408
    [Abstract] [Full Text] [Related]

  • 17. The interaction of RS 25259-197, a potent and selective antagonist, with 5-HT3 receptors, in vitro.
    Wong EH, Clark R, Leung E, Loury D, Bonhaus DW, Jakeman L, Parnes H, Whiting RL, Eglen RM.
    Br J Pharmacol; 1995 Feb 06; 114(4):851-9. PubMed ID: 7773546
    [Abstract] [Full Text] [Related]

  • 18. Development of potent serotonin-3 (5-HT3) receptor antagonists. I. Structure-activity relationships of 2-alkoxy-4-amino-5-chlorobenzamide derivatives.
    Harada H, Morie T, Hirokawa Y, Yoshida N, Kato S.
    Chem Pharm Bull (Tokyo); 1995 Aug 06; 43(8):1364-78. PubMed ID: 7553982
    [Abstract] [Full Text] [Related]

  • 19. Binding of arylpiperazines to 5-HT3 serotonin receptors: results of a structure-affinity study.
    Glennon RA, Ismaiel AE, McCarthy BG, Peroutka SJ.
    Eur J Pharmacol; 1989 Sep 22; 168(3):387-92. PubMed ID: 2583244
    [Abstract] [Full Text] [Related]

  • 20. Novel antagonists of 5-HT3 receptors. Synthesis and biological evaluation of piperazinylquinoxaline derivatives.
    Monge A, Palop JA, Del Castillo JC, Calderó JM, Roca J, Romero G, Del Río J, Lasheras B.
    J Med Chem; 1993 Sep 17; 36(19):2745-50. PubMed ID: 8410988
    [Abstract] [Full Text] [Related]

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