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Journal Abstract Search

253 related items for PubMed ID: 14871988

  • 1. The role of alpha-folate receptor-mediated transport in the antitumor activity of antifolate drugs.
    Theti DS, Jackman AL.
    Clin Cancer Res; 2004 Feb 01; 10(3):1080-9. PubMed ID: 14871988
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  • 2. Selective delivery of CB300638, a cyclopenta[g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the alpha-isoform of the folate receptor.
    Theti DS, Bavetsias V, Skelton LA, Titley J, Gibbs D, Jansen G, Jackman AL.
    Cancer Res; 2003 Jul 01; 63(13):3612-8. PubMed ID: 12839949
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  • 4. Determinants of the activities of antifolates delivered into cells by folate-receptor-mediated endocytosis.
    Zhao R, Visentin M, Goldman ID.
    Cancer Chemother Pharmacol; 2015 Jun 01; 75(6):1163-73. PubMed ID: 25847479
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  • 5. Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier.
    Wang Y, Zhao R, Goldman ID.
    Clin Cancer Res; 2004 Sep 15; 10(18 Pt 1):6256-64. PubMed ID: 15448015
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  • 7. The inverse relationship between reduced folate carrier function and pemetrexed activity in a human colon cancer cell line.
    Chattopadhyay S, Zhao R, Krupenko SA, Krupenko N, Goldman ID.
    Mol Cancer Ther; 2006 Feb 15; 5(2):438-49. PubMed ID: 16505119
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  • 9. Effects of the antifolates pemetrexed and CB3717 on the tissue distribution of (99m)Tc-EC20 in xenografted and syngeneic tumor-bearing mice.
    Müller C, Reddy JA, Leamon CP, Schibli R.
    Mol Pharm; 2010 Apr 05; 7(2):597-604. PubMed ID: 20199053
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  • 11. Selective preservation of pemetrexed pharmacological activity in HeLa cells lacking the reduced folate carrier: association with the presence of a secondary transport pathway.
    Zhao R, Hanscom M, Chattopadhyay S, Goldman ID.
    Cancer Res; 2004 May 01; 64(9):3313-9. PubMed ID: 15126375
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  • 12. Lack of impact of the loss of constitutive folate receptor alpha expression, achieved by RNA Interference, on the activity of the new generation antifolate pemetrexed in HeLa cells.
    Chattopadhyay S, Wang Y, Zhao R, Goldman ID.
    Clin Cancer Res; 2004 Dec 01; 10(23):7986-93. PubMed ID: 15585634
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  • 13. BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors.
    Gibbs DD, Theti DS, Wood N, Green M, Raynaud F, Valenti M, Forster MD, Mitchell F, Bavetsias V, Henderson E, Jackman AL.
    Cancer Res; 2005 Dec 15; 65(24):11721-8. PubMed ID: 16357184
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  • 19. Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression.
    Sigmond J, Backus HH, Wouters D, Temmink OH, Jansen G, Peters GJ.
    Biochem Pharmacol; 2003 Aug 01; 66(3):431-8. PubMed ID: 12907242
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