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364 related items for PubMed ID: 14962946

  • 1. Cholesterol 7alpha-hydroxylase deficiency in mice on an APOE*3-Leiden background impairs very-low-density lipoprotein production.
    Post SM, Groenendijk M, Solaas K, Rensen PC, Princen HM.
    Arterioscler Thromb Vasc Biol; 2004 Apr; 24(4):768-74. PubMed ID: 14962946
    [Abstract] [Full Text] [Related]

  • 2. Cafestol increases serum cholesterol levels in apolipoprotein E*3-Leiden transgenic mice by suppression of bile acid synthesis.
    Post SM, de Roos B, Vermeulen M, Afman L, Jong MC, Dahlmans VE, Havekes LM, Stellaard F, Katan MB, Princen HM.
    Arterioscler Thromb Vasc Biol; 2000 Jun; 20(6):1551-6. PubMed ID: 10845871
    [Abstract] [Full Text] [Related]

  • 3. Rosuvastatin reduces plasma lipids by inhibiting VLDL production and enhancing hepatobiliary lipid excretion in ApoE*3-leiden mice.
    Delsing DJ, Post SM, Groenendijk M, Solaas K, van der Boom H, van Duyvenvoorde W, de Wit EC, Bloks VW, Kuipers F, Havekes LM, Princen HM.
    J Cardiovasc Pharmacol; 2005 Jan; 45(1):53-60. PubMed ID: 15613980
    [Abstract] [Full Text] [Related]

  • 4. Cholesterol 7alpha-hydroxylase deficiency in mice on an APOE*3-Leiden background increases hepatic ABCA1 mRNA expression and HDL-cholesterol.
    Post SM, Groenendijk M, van der Hoogt CC, Fievet C, Luc G, Hoekstra M, Princen HM, Staels B, Rensen PC.
    Arterioscler Thromb Vasc Biol; 2006 Dec; 26(12):2724-30. PubMed ID: 17008588
    [Abstract] [Full Text] [Related]

  • 5. Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7alpha-hydroxylase.
    Miyake JH, Doung XD, Strauss W, Moore GL, Castellani LW, Curtiss LK, Taylor JM, Davis RA.
    J Biol Chem; 2001 Jun 29; 276(26):23304-11. PubMed ID: 11323427
    [Abstract] [Full Text] [Related]

  • 6. Dietary plant stanol esters reduce VLDL cholesterol secretion and bile saturation in apolipoprotein E*3-Leiden transgenic mice.
    Volger OL, van der Boom H, de Wit EC, van Duyvenvoorde W, Hornstra G, Plat J, Havekes LM, Mensink RP, Princen HM.
    Arterioscler Thromb Vasc Biol; 2001 Jun 29; 21(6):1046-52. PubMed ID: 11397718
    [Abstract] [Full Text] [Related]

  • 7. Altered lipid metabolism in apolipoprotein E-deficient mice does not affect cholesterol balance across the liver.
    Kuipers F, van Ree JM, Hofker MH, Wolters H, In't Veld G, Havinga R, Vonk RJ, Princen HM, Havekes LM.
    Hepatology; 1996 Jul 29; 24(1):241-7. PubMed ID: 8707269
    [Abstract] [Full Text] [Related]

  • 8. Apolipoprotein E2 (Lys146-->Gln) causes hypertriglyceridemia due to an apolipoprotein E variant-specific inhibition of lipolysis of very low density lipoproteins-triglycerides.
    de Beer F, van Dijk KW, Jong MC, van Vark LC, van der Zee A, Hofker MH, Fallaux FJ, Hoeben RC, Smelt AH, Havekes LM.
    Arterioscler Thromb Vasc Biol; 2000 Jul 29; 20(7):1800-6. PubMed ID: 10894820
    [Abstract] [Full Text] [Related]

  • 9. Evidence that cholesteryl ester and triglyceride accumulation in J774 macrophages induced by very low density lipoprotein subfractions occurs by different mechanisms.
    Evans AJ, Sawyez CG, Wolfe BM, Connelly PW, Maguire GF, Huff MW.
    J Lipid Res; 1993 May 29; 34(5):703-17. PubMed ID: 8509711
    [Abstract] [Full Text] [Related]

  • 10. Modulation of very low density lipoprotein production and clearance contributes to age- and gender- dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic mice.
    van Vlijmen BJ, van 't Hof HB, Mol MJ, van der Boom H, van der Zee A, Frants RR, Hofker MH, Havekes LM.
    J Clin Invest; 1996 Mar 01; 97(5):1184-92. PubMed ID: 8636429
    [Abstract] [Full Text] [Related]

  • 11. Characterization of very low density lipoproteins and intermediate density lipoproteins of normo- and hyperlipidemic apolipoprotein E-2 homozygotes.
    Schmitz G, Assmann G, Augustin J, Dirkes-Kersting A, Brennhaüsen B, Karoff C.
    J Lipid Res; 1985 Mar 01; 26(3):316-26. PubMed ID: 3989390
    [Abstract] [Full Text] [Related]

  • 12. Hepatic lipid accumulation, altered very low density lipoprotein formation and apolipoprotein E deposition in apolipoprotein E3-Leiden transgenic mice.
    Mensenkamp AR, van Luyn MJ, van Goor H, Bloks V, Apostel F, Greeve J, Hofker MH, Jong MC, van Vlijmen BJ, Havekes LM, Kuipers F.
    J Hepatol; 2000 Aug 01; 33(2):189-98. PubMed ID: 10952236
    [Abstract] [Full Text] [Related]

  • 13. Cholesterol-lowering effects and potential mechanisms of different polar extracts from Cyclocarya paliurus leave in hyperlipidemic mice.
    Jiang C, Wang Q, Wei Y, Yao N, Wu Z, Ma Y, Lin Z, Zhao M, Che C, Yao X, Zhang J, Yin Z.
    J Ethnopharmacol; 2015 Dec 24; 176():17-26. PubMed ID: 26477373
    [Abstract] [Full Text] [Related]

  • 14. Cholesterol feeding of mice expressing cholesterol 7alpha-hydroxylase increases bile acid pool size despite decreased enzyme activity.
    Tiemann M, Han Z, Soccio R, Bollineni J, Shefer S, Sehayek E, Breslow JL.
    Proc Natl Acad Sci U S A; 2004 Feb 17; 101(7):1846-51. PubMed ID: 14762172
    [Abstract] [Full Text] [Related]

  • 15. Effects of dietary fish oil on serum lipids and VLDL kinetics in hyperlipidemic apolipoprotein E*3-Leiden transgenic mice.
    van Vlijmen BJ, Mensink RP, van 't Hof HB, Offermans RF, Hofker MH, Havekes LM.
    J Lipid Res; 1998 Jun 17; 39(6):1181-8. PubMed ID: 9643349
    [Abstract] [Full Text] [Related]

  • 16. Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice.
    Erickson SK, Lear SR, Deane S, Dubrac S, Huling SL, Nguyen L, Bollineni JS, Shefer S, Hyogo H, Cohen DE, Shneider B, Sehayek E, Ananthanarayanan M, Balasubramaniyan N, Suchy FJ, Batta AK, Salen G.
    J Lipid Res; 2003 May 17; 44(5):1001-9. PubMed ID: 12588950
    [Abstract] [Full Text] [Related]

  • 17. Apolipoprotein E*3-Leiden transgenic mice as a test model for hypolipidaemic drugs.
    van Vlijmen BJ, Pearce NJ, Bergö M, Staels B, Yates JW, Gribble AD, Bond BC, Hofker MH, Havekes LM, Groot PH.
    Arzneimittelforschung; 1998 Apr 17; 48(4):396-402. PubMed ID: 9608883
    [Abstract] [Full Text] [Related]

  • 18. Modification of type III VLDL, their remnants, and VLDL from ApoE-knockout mice by p-hydroxyphenylacetaldehyde, a product of myeloperoxidase activity, causes marked cholesteryl ester accumulation in macrophages.
    Whitman SC, Hazen SL, Miller DB, Hegele RA, Heinecke JW, Huff MW.
    Arterioscler Thromb Vasc Biol; 1999 May 17; 19(5):1238-49. PubMed ID: 10323775
    [Abstract] [Full Text] [Related]

  • 19. Alternate pathways of bile acid synthesis in the cholesterol 7alpha-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding.
    Schwarz M, Russell DW, Dietschy JM, Turley SD.
    J Lipid Res; 2001 Oct 17; 42(10):1594-603. PubMed ID: 11590215
    [Abstract] [Full Text] [Related]

  • 20. Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver.
    Mensenkamp AR, Jong MC, van Goor H, van Luyn MJ, Bloks V, Havinga R, Voshol PJ, Hofker MH, van Dijk KW, Havekes LM, Kuipers F.
    J Biol Chem; 1999 Dec 10; 274(50):35711-8. PubMed ID: 10585451
    [Abstract] [Full Text] [Related]


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