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Journal Abstract Search

380 related items for PubMed ID: 14977865

  • 1. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).
    Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S.
    Drug Metab Dispos; 2004 Mar; 32(3):314-20. PubMed ID: 14977865
    [Abstract] [Full Text] [Related]

  • 2. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
    Kaji H, Kume T.
    Drug Metab Dispos; 2005 Mar; 33(3):403-12. PubMed ID: 15608137
    [Abstract] [Full Text] [Related]

  • 3. Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.
    Innocenti F, Iyer L, Ramírez J, Green MD, Ratain MJ.
    Drug Metab Dispos; 2001 May; 29(5):686-92. PubMed ID: 11302935
    [Abstract] [Full Text] [Related]

  • 4. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of 3-hydroxydesloratadine.
    Ghosal A, Yuan Y, Hapangama N, Su AD, Alvarez N, Chowdhury SK, Alton KB, Patrick JE, Zbaida S.
    Biopharm Drug Dispos; 2004 Sep; 25(6):243-52. PubMed ID: 15334623
    [Abstract] [Full Text] [Related]

  • 5. Disposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjects.
    Patrick JE, Kosoglou T, Stauber KL, Alton KB, Maxwell SE, Zhu Y, Statkevich P, Iannucci R, Chowdhury S, Affrime M, Cayen MN.
    Drug Metab Dispos; 2002 Apr; 30(4):430-7. PubMed ID: 11901097
    [Abstract] [Full Text] [Related]

  • 6. Carboxyl-glucuronidation of mitiglinide by human UDP-glucuronosyltransferases.
    Yu L, Lu S, Lin Y, Zeng S.
    Biochem Pharmacol; 2007 Jun 01; 73(11):1842-51. PubMed ID: 17359941
    [Abstract] [Full Text] [Related]

  • 7. In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases.
    Tong Z, Li H, Goljer I, McConnell O, Chandrasekaran A.
    Drug Metab Dispos; 2007 Dec 01; 35(12):2203-10. PubMed ID: 17875670
    [Abstract] [Full Text] [Related]

  • 8. Characterization of 2-[[4-[[2-(1H-tetrazol-5-ylmethyl)phenyl]methoxy]methyl]quinoline N-glucuronidation by in vitro and in vivo approaches.
    Stevens JC, Fayer JL, Cassidy KC.
    Drug Metab Dispos; 2001 Mar 01; 29(3):289-95. PubMed ID: 11181497
    [Abstract] [Full Text] [Related]

  • 9. Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.
    Yamanaka H, Nakajima M, Katoh M, Kanoh A, Tamura O, Ishibashi H, Yokoi T.
    Drug Metab Dispos; 2005 Jan 01; 33(1):23-30. PubMed ID: 15470160
    [Abstract] [Full Text] [Related]

  • 10. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
    Fujiwara R, Nakajima M, Yamanaka H, Katoh M, Yokoi T.
    Drug Metab Dispos; 2008 Feb 01; 36(2):361-7. PubMed ID: 17998297
    [Abstract] [Full Text] [Related]

  • 11. UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for etoposide glucuronidation in human liver and intestinal microsomes: structural characterization of phenolic and alcoholic glucuronides of etoposide and estimation of enzyme kinetics.
    Wen Z, Tallman MN, Ali SY, Smith PC.
    Drug Metab Dispos; 2007 Mar 01; 35(3):371-80. PubMed ID: 17151191
    [Abstract] [Full Text] [Related]

  • 12. Human UDP-glucuronosyltransferase isoforms involved in bisphenol A glucuronidation.
    Hanioka N, Naito T, Narimatsu S.
    Chemosphere; 2008 Dec 01; 74(1):33-6. PubMed ID: 18990428
    [Abstract] [Full Text] [Related]

  • 13. A humanized UGT1 mouse model expressing the UGT1A1*28 allele for assessing drug clearance by UGT1A1-dependent glucuronidation.
    Cai H, Nguyen N, Peterkin V, Yang YS, Hotz K, La Placa DB, Chen S, Tukey RH, Stevens JC.
    Drug Metab Dispos; 2010 May 01; 38(5):879-86. PubMed ID: 20124398
    [Abstract] [Full Text] [Related]

  • 14. The role of human UDP-glucuronyltransferases on the formation of the methylenedioxymethamphetamine (ecstasy) phase II metabolites R- and S-3-methoxymethamphetamine 4-O-glucuronides.
    Schwaninger AE, Meyer MR, Zapp J, Maurer HH.
    Drug Metab Dispos; 2009 Nov 01; 37(11):2212-20. PubMed ID: 19666989
    [Abstract] [Full Text] [Related]

  • 15. Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol.
    Chen M, LeDuc B, Kerr S, Howe D, Williams DA.
    Drug Metab Dispos; 2010 Mar 01; 38(3):368-75. PubMed ID: 20008037
    [Abstract] [Full Text] [Related]

  • 16. Involvement of multiple UDP-glucuronosyltransferase 1A isoforms in glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes.
    Nakajima M, Sakata N, Ohashi N, Kume T, Yokoi T.
    Drug Metab Dispos; 2002 Nov 01; 30(11):1250-6. PubMed ID: 12386132
    [Abstract] [Full Text] [Related]

  • 17. Human metabolism of nebicapone (BIA 3-202), a novel catechol-o-methyltransferase inhibitor: characterization of in vitro glucuronidation.
    Loureiro AI, Bonifácio MJ, Fernandes-Lopes C, Almeida L, Wright LC, Soares-Da-Silva P.
    Drug Metab Dispos; 2006 Nov 01; 34(11):1856-62. PubMed ID: 16790555
    [Abstract] [Full Text] [Related]

  • 18. Glucuronidation of etoposide in human liver microsomes is specifically catalyzed by UDP-glucuronosyltransferase 1A1.
    Watanabe Y, Nakajima M, Ohashi N, Kume T, Yokoi T.
    Drug Metab Dispos; 2003 May 01; 31(5):589-95. PubMed ID: 12695347
    [Abstract] [Full Text] [Related]

  • 19. Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.
    Shiraga T, Yajima K, Suzuki K, Suzuki K, Hashimoto T, Iwatsubo T, Miyashita A, Usui T.
    Drug Metab Dispos; 2012 Feb 01; 40(2):276-82. PubMed ID: 22031623
    [Abstract] [Full Text] [Related]

  • 20. Identification of a novel N-carbamoyl glucuronide: in vitro, in vivo, and mechanistic studies.
    Gunduz M, Argikar UA, Baeschlin D, Ferreira S, Hosagrahara V, Harriman S.
    Drug Metab Dispos; 2010 Mar 01; 38(3):361-7. PubMed ID: 20008038
    [Abstract] [Full Text] [Related]

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