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537 related items for PubMed ID: 14977868

  • 1. In vitro sulfoxidation of thioether compounds by human cytochrome P450 and flavin-containing monooxygenase isoforms with particular reference to the CYP2C subfamily.
    Usmani KA, Karoly ED, Hodgson E, Rose RL.
    Drug Metab Dispos; 2004 Mar; 32(3):333-9. PubMed ID: 14977868
    [Abstract] [Full Text] [Related]

  • 2. Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine.
    Giancarlo GM, Venkatakrishnan K, Granda BW, von Moltke LL, Greenblatt DJ.
    Eur J Clin Pharmacol; 2001 Apr; 57(1):31-6. PubMed ID: 11372587
    [Abstract] [Full Text] [Related]

  • 3. Human cytochrome p450 enzymes of importance for the bioactivation of methyleugenol to the proximate carcinogen 1'-hydroxymethyleugenol.
    Jeurissen SM, Bogaards JJ, Boersma MG, ter Horst JP, Awad HM, Fiamegos YC, van Beek TA, Alink GM, Sudhölter EJ, Cnubben NH, Rietjens IM.
    Chem Res Toxicol; 2006 Jan; 19(1):111-6. PubMed ID: 16411663
    [Abstract] [Full Text] [Related]

  • 4. Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine.
    Wójcikowski J, Pichard-Garcia L, Maurel P, Daniel WA.
    Br J Pharmacol; 2003 Apr; 138(8):1465-74. PubMed ID: 12721102
    [Abstract] [Full Text] [Related]

  • 5. Metabolism of sesamin by cytochrome P450 in human liver microsomes.
    Yasuda K, Ikushiro S, Kamakura M, Ohta M, Sakaki T.
    Drug Metab Dispos; 2010 Dec; 38(12):2117-23. PubMed ID: 20851877
    [Abstract] [Full Text] [Related]

  • 6. Comparison of the substrate specificities of human liver cytochrome P450s 2C9 and 2C18: application to the design of a specific substrate of CYP 2C18.
    Minoletti C, Dijols S, Dansette PM, Mansuy D.
    Biochemistry; 1999 Jun 15; 38(24):7828-36. PubMed ID: 10387023
    [Abstract] [Full Text] [Related]

  • 7. Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid.
    Taguchi K, Konishi T, Nishikawa H, Kitamura S.
    Xenobiotica; 1999 Sep 15; 29(9):899-907. PubMed ID: 10548450
    [Abstract] [Full Text] [Related]

  • 8. Synthesis of sulfaphenazole derivatives and their use as inhibitors and tools for comparing the active sites of human liver cytochromes P450 of the 2C subfamily.
    Ha-Duong NT, Dijols S, Marques-Soares C, Minoletti C, Dansette PM, Mansuy D.
    J Med Chem; 2001 Oct 25; 44(22):3622-31. PubMed ID: 11606127
    [Abstract] [Full Text] [Related]

  • 9. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
    Venkatakrishnan K, von Moltke LL, Duan SX, Fleishaker JC, Shader RI, Greenblatt DJ.
    J Pharm Pharmacol; 1998 Mar 25; 50(3):265-74. PubMed ID: 9600717
    [Abstract] [Full Text] [Related]

  • 10. Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily.
    Ono S, Hatanaka T, Miyazawa S, Tsutsui M, Aoyama T, Gonzalez FJ, Satoh T.
    Xenobiotica; 1996 Nov 25; 26(11):1155-66. PubMed ID: 8948091
    [Abstract] [Full Text] [Related]

  • 11. A convenient method to discriminate between cytochrome P450 enzymes and flavin-containing monooxygenases in human liver microsomes.
    Grothusen A, Hardt J, Bräutigam L, Lang D, Böcker R.
    Arch Toxicol; 1996 Nov 25; 71(1-2):64-71. PubMed ID: 9010587
    [Abstract] [Full Text] [Related]

  • 12. Extrahepatic metabolism of carbamate and organophosphate thioether compounds by the flavin-containing monooxygenase and cytochrome P450 systems.
    Furnes B, Schlenk D.
    Drug Metab Dispos; 2005 Feb 25; 33(2):214-8. PubMed ID: 15547051
    [Abstract] [Full Text] [Related]

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  • 16. Lack of single-dose disulfiram effects on cytochrome P-450 2C9, 2C19, 2D6, and 3A4 activities: evidence for specificity toward P-450 2E1.
    Kharasch ED, Hankins DC, Jubert C, Thummel KE, Taraday JK.
    Drug Metab Dispos; 1999 Jun 25; 27(6):717-23. PubMed ID: 10348802
    [Abstract] [Full Text] [Related]

  • 17. Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes.
    Yamazaki H, Shimada T.
    Xenobiotica; 1999 Mar 25; 29(3):231-41. PubMed ID: 10219964
    [Abstract] [Full Text] [Related]

  • 18. Diclofenac and its derivatives as tools for studying human cytochromes P450 active sites: particular efficiency and regioselectivity of P450 2Cs.
    Mancy A, Antignac M, Minoletti C, Dijols S, Mouries V, Duong NT, Battioni P, Dansette PM, Mansuy D.
    Biochemistry; 1999 Oct 26; 38(43):14264-70. PubMed ID: 10572000
    [Abstract] [Full Text] [Related]

  • 19. Studies of flurbiprofen 4'-hydroxylation. Additional evidence suggesting the sole involvement of cytochrome P450 2C9.
    Tracy TS, Marra C, Wrighton SA, Gonzalez FJ, Korzekwa KR.
    Biochem Pharmacol; 1996 Oct 25; 52(8):1305-9. PubMed ID: 8937439
    [Abstract] [Full Text] [Related]

  • 20. In vitro inhibition of the cytochrome P450 (CYP450) system by the antiplatelet drug ticlopidine: potent effect on CYP2C19 and CYP2D6.
    Ko JW, Desta Z, Soukhova NV, Tracy T, Flockhart DA.
    Br J Clin Pharmacol; 2000 Apr 25; 49(4):343-51. PubMed ID: 10759690
    [Abstract] [Full Text] [Related]

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